Special

MmuINT0103540 @ mm9

Intron Retention

Gene
ENSMUSG00000040752 | Myh6
Description
myosin, heavy polypeptide 6, cardiac muscle, alpha [Source:MGI Symbol;Acc:MGI:97255]
Coordinates
chr14:55572535-55575475:-
Coord C1 exon
chr14:55575339-55575475
Coord A exon
chr14:55572791-55575338
Coord C2 exon
chr14:55572535-55572790
Length
2548 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
ATTGCACTCTTTCTGGTCAGGGA
3' ss Score
6.61
Exon sequences
Seq C1 exon
GTGTTCTTCAAGGCGGGCCTGCTGGGGCTGCTCGAGGAGATGCGAGATGAGAGGCTGAGCCGTATCATCACCAGAATCCAGGCCCAGGCCCGAGGGCAGCTCATGCGCATTGAGTTCAAGAAGATAGTGGAACGCAG
Seq A exon
GTGAGGCGGGCACGGAGGGCCAGTGTCTGAGAGGACGGCCAGCAGTGTGGAATAGTTACAGGGATCTGCATTCAGACCCTGGCTCCATTGATTGCTGTGATGTGGACAAGTGAGTCTACTGCAGTAGATTTCATTTTGACCTATTTTGAAAAGACTCCATGACACTTTAAAACACCAGATGAATTTAAGAAGGCTGGCCTGTTGTTTATAGATGTATAAATTAGTATAGGATTTTGAGAAGCTTTTTATTCTCTTTCTTAATGTACCTAGTTTTTTTTTTAATTATTAGATTCATTTATGTATTGGGGTAATGCTGTATCACATATATGAAGGTCAGAGAACAATCCACAGAGTTGGTTCTCTCGATTGATTGATTGATTGATTGATTGATTGATTGATTGATTGACTGACTGAGAAAAGGTTTCTCTGTGTAGCCCTGGTTGTCCTTGAACTCTCTCTGTAGAGAGGCTGGCCTCAAACGCAGAGATCTGCCTACCTTTGTATCCACCATAATGCTGACCTTAAAGGCATATACTGCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTGCTATTGTTCACTGTTGTTCTACTATGTGGGTCCAAGGGATAAACTGAGGTCATCAGACAGCTTCTACCTGCCGAACCACCTCAAAGGCTCTTATTCTCTCTGTGTATATAAGCCACCTCACATTTATTTGTGTCTTTTGTGTGTGCATGTGTATATGGTACGTGTGCACATGTGTCCGTGCATGAAGCAGGGTGCATGTGGAGGTCAGAGGACAGCATGCAGGACCAGATCTCTGCTCCTACCATGTTCAGTCACAGGGACCAGACTCTGGCTGTGATGATGTTTGACAGTGAGTGCCTTTGCCTGCTGAGCCATCTTGCCAGCCTGTTCTCTTCTTTAAAGTTGAACTATCACATACTTTTAATTTTGTTAGGTTTTTGACAAATTCATACAATACTCAGTGATCATATTGACCACATTGCCCTCCACTCCTGCTGGCCCCTTCTTATTCCTAACCAATCCCCTCTGCTTCTGTGTCTTTATTTTTTATCATCACATACTGTCCTTTCCATTTCTGAATATAGTCTCCCAGAGAAACCACTTCACATGGTACACCAGGAGACAAAAGAAAAGAAAAAAAAATCTATCTTCATGGCAGTCTTAATCTTAAGAGCAGAGATCTAGCCGGGCGTGGTGTCGCATGCCTTTAATCCCAGCACTCAGGAGGCAGAGGCAGGTGGATTTCTGAGTTCGAGGCCAGTCTGGTCTACAGAGTGAGTTCCAGGACAGCCAGGGCTACACAAAGAAACCCTGTCTGGAAAAAAAAAAAAAAAAAAAAAAAAGAGCAGAGACCTAGAAAGGACCTCAACTTCCATCTAAAGGAGTGTGGCTAAAGAGTATCCCAGCCATTTGGTGAAATACTATCTAACTGTGAAAATGTCTATGCTACAGCGACATGGTATAAAAGCAATTCATACAAGCAGACATACAGTATGACACAGTATTTATCTATGAAGCTCAGAAATCATGACAACAGAAGTTCATTGTTTAAAGTGACCTTTGCATATTGTCTAAAACACTTTTTTTTTTAAAAAAAAGAAGTAAAAAAAATTGAGGAACCAAGGAAATGGCTCAGGTAGGGTTTGCTGTGCAAACATGAACTCTTATGCTCCTTCTCCAGCAGCCACATGAAAAGCTGAGTGTAGCTGCCCAATCCATAACCCCAGCCCTGTGGGGCAGAGAGAGCAGGGTCAGTAGAGCTCCCTGCATACCAGCCTAACGGAAACAGCAAGCCCCAGGTTCAGTGCCTTAAGGCAGAGAACGCCAGAAGGAGACAGCTCATGTCCTCCTCTGGTCTCTAGGCACACATGTACCCATGTATACTCACATGTGTGTGCCTACATAAAACACACGCACAAGCACAAATTAAAAAAAGAAAAACTGAGATGGGTGTCTCATTACATATCTAGGCAGGGCAGGCTTGGAGCTTACTATGTAGACCAGGCTAACCTCGAACCACAGCTGACAAGCACAAAAAATCTACACTACCACACCCTGCCAAAAAATAGTAATAATTTTTAAGTAAGAAAATTAAAAACAAGTTTAATAGCAGTGGCTGCTTCTAGTTGAGGGCCAGAGAAGGTGGAAAGGAGCCCACTTGCAGCTCAGTAGTTGAATGCTCCATCTCCTGCTCAGCTGGTGGGCTCCCAAGCAGTTATTTTGTAGCATTCTGAGATGTAAAATGCTACATAGTCTGTATTTGAAGGTATCCCAAAAATGAACACTGAACAGGTAGACCTCTCAGTGGCTTCTGTTACTATTGCTGCCCCAGTAGAGGAATGCATACCATACTTTTGTTGAAATCATAAGGAGTGAGGCTACAATGCCCCTTGTCCTTTGTGCCTACAAACTTGCTCAGACAGAGGAGGCCAGGGCAACTGGTCCCATGCCTGAGGAGACTTCTTTCTAGAGTTCTTCCTGATTGCACTCTTTCTGGTCAG
Seq C2 exon
GGATGCCCTGCTGGTTATCCAGTGGAACATTCGGGCCTTCATGGGGGTCAAGAATTGGCCATGGATGAAGCTCTACTTCAAGATCAAACCGCTGCTGAAGAGCGCAGAGACGGAGAAGGAGATGGCCAACATGAAGGAGGAGTTTGGGCGAGTCAAAGATGCACTGGAGAAGTCTGAGGCTCGCCGCAAGGAGCTGGAGGAGAAGATGGTGTCCCTGCTGCAGGAGAAGAATGACCTACAGCTCCAAGTGCAGGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000040752-Myh6:NM_001164171:20
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.058
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0006316=Myosin_head=PD(0.4=6.5),PF0061222=IQ=WD(100=45.7)

							
A:
NA

							
C2:
PF0157614=Myosin_tail_1=PU(28.0=61.6)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000080538





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000115326
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr14:23394324-23396283 
LOW PSI
HsaINT0107810
(MYH6)
Human
(hg19)
chr14:23863533-23865492 
LOW PSI
HsaINT0107810
(MYH6)
Rat
(rn6)
chr15:33618534-33621240 
LOW PSI
RnoINT0096508
(Myh6)
Cow
(bosTau6)
chr10:21361481-21363034 
LOW PSI
BtaINT0097334
(MYH7)
Chicken
(galGal4)
chr19:18127-18235 
LOW PSI
GgaINT0132874
(MYH7)
Chicken
(galGal3)
chr18:392739-392840 
LOW PSI
GgaINT0129360
(MYH1)
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"