HsaINT0107810 @ hg38
Intron Retention
Gene
ENSG00000197616 | MYH6
Description
myosin heavy chain 6 [Source:HGNC Symbol;Acc:HGNC:7576]
Coordinates
chr14:23394068-23396420:-
Coord C1 exon
chr14:23396284-23396420
Coord A exon
chr14:23394324-23396283
Coord C2 exon
chr14:23394068-23394323
Length
1960 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
3' ss Seq
CCTCCACGTTTCCTTGCCAGGGA
3' ss Score
9.06
Exon sequences
Seq C1 exon
GTGTTCTTCAAGGCAGGGCTGCTTGGGCTGCTGGAGGAGATGCGGGATGAGAGGCTGAGCCGCATCATCACGCGCATGCAGGCCCAAGCCCGGGGCCAGCTCATGCGCATTGAGTTCAAGAAGATAGTGGAACGCAG
Seq A exon
GTGAGACAGGAGGAAAAGGGAGGCATGCACTAGAGATGTAGAGGCAGATCCGCAATGTCAACTAGTGTGGGTCAGAAGACCTGGGTTCAGACCTACCAGCTGGCCTGGGCAAGTTACTTTACCACTTCGAATCTCATTGCAAATTCTTCTTCTTCTTCTTCTTCTTCTTTTTTTTTTTTTAAAGAAACTTCTCTATAGGAAAATGCAAATTAAGACACCAATGAAATACCATTTTAAAACACTAGACTTTGCTTGCTCAGATGGTCTACAAATTTTAAAAAATGAAAGAAACAAGTAGATAAAAATAAAATGAAAGGAAAAATAATTTTTAAAAGTTTTAAAAATCACTAGACTGACAAAAATTAAGAAGCCTGACCCACTGCTTACAGATGTGTAAATTAGTGCAACTTCCTAGGAAAACAGTTTATCACTATCTTTTAAAGTTGAACAGCTGCAGGCCAGGCGCGGTGGCTCATGCCTGAAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACGAGGTCAGGAGATCAAAACCATCCTGGCTAACATGGTGAAACCCCATCTCTACTAAAAAAATACAAAAAATTAGCCGGGTGTGGTGGCAGATGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATGGCATGAGCCCGGGAGGCAGAGCTTGCAGTGAGCCAAGATCGAGCCACTGCACTCTAGCCTGGGCGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAGTTGAACAGCTGCATACTTCTCCATTCCACTCCTGAGTACATTCCTACAGAGAAACTCTTATACATGTACACCATGACATGAAAAATAATCTTTTAGCAGCATTGGTCATAATAGCAAAGATCTTAAAACAACTTGAATTTCCATCCACAGGGGAATGGGTAAATAGTATTACAGTCATTCAGTGGAATATTATAAAACAGTGAAAAGATGTGAACTCCAACTACATGATACAATATGTTTGAACATTAAAGCATATTGTTAGTAAACAAAGGCAAATCTTGGAAGGATACATACAGTATGATGCAATTTTTATAAAGCTCATAAATAATCAAAACCAGCCATTCATTGTTTAAAGATACATACATATGGCTGGGCACAGTGGCTTATGCCTGTAACCCCAGCACTTTGGGAGGCTAAGGCAGGCGGATCACCTGAGGTCAGGAGATGGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAACTACAAAAATTAGCTGGGCATGGTGGCAGGCACCTGTAATTCCAGCTACTCAGGAGCTGAGGCAGGAGAATCGCTTGAATCCGGGTGGCAGAGGTTGCAGTGAGCCGAGATTGTGCCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCATCTCAAAATAAATAAAGTAAAATAAAAATAAAGATACATTCATATGTGGTTAAAGTAATTTTTGAAAAAGCAAGGAAAGGAAAAATAAGATTCAGAGTGGCGGCTGCTCCTGGCGGGGTGACAGGGGTGTAGGAAGGAACGCACAGGTAGATCAATGGCTGGTAACATTTCAGCTCCTGTTTCAGTGGTAGGTTCATGGATAGTCATTTTGCTTTCATGCTGCATAACTTACATACTTATTATAGACATTCTTATATGTAAACCCCTACATAATTTTTAACATATTTGAAGTTCTTATGAGAATAGAAAAACCAAACAGAGTAGACATTCTATAAGTGGTAGTTTCCATTACCACTAATATCCCAGCTGGGAGGATATAAACTGCCCTTTCATCAAATTGATTAATAAATATTTATCAAGCAACTCCATGTTCAGTGTAGTGATGTTGGAGGTGGGTGTGCACAAGAAGGAAGTCTACGTGCCTACGAACTTGCTTAGTAGGGCCCATGATTGGGAAGCTCTCTTTTATAGTGCCCCACCCTGCCTCCACGTTTCCTTGCCAG
Seq C2 exon
GGATGCCCTGCTGGTAATCCAGTGGAACATTCGGGCCTTCATGGGGGTCAAGAATTGGCCCTGGATGAAGCTCTACTTCAAGATCAAGCCGCTGCTGAAGAGCGCAGAGACGGAGAAGGAGATGGCCACCATGAAGGAAGAGTTCGGGCGCATCAAAGAGACGCTGGAGAAGTCCGAGGCTCGCCGCAAGGAGCTGGAGGAGAAGATGGTGTCCCTGCTGCAGGAGAAGAATGACCTGCAGCTCCAAGTGCAGGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197616:ENST00000356287:19
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.070
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PD(0.4=6.5)
A:
NA
C2:
PF0157614=Myosin_tail_1=PU(27.0=61.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGTTCTTCAAGGCAGGGCTG
R:
ACCATCTTCTCCTCCAGCTCC
Band lengths:
347-2307
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development