Special

MmuINT0103868 @ mm9

Intron Retention

Gene
ENSMUSG00000022272 | Myo10
Description
myosin X [Source:MGI Symbol;Acc:MGI:107716]
Coordinates
chr15:25669042-25672204:+
Coord C1 exon
chr15:25669042-25669124
Coord A exon
chr15:25669125-25672095
Coord C2 exon
chr15:25672096-25672204
Length
2971 bp
Sequences
Splice sites
5' ss Seq
CAGGTATGC
5' ss Score
9.37
3' ss Seq
TCTGTGCTCCCTTCACACAGGTT
3' ss Score
10.52
Exon sequences
Seq C1 exon
GTGCAGTATGATGTCCGAGGCATCTTGGAAAAGAACAGAGACACATTCAGAGATGACCTTCTCAACCTGCTCAGGGAAAGCAG
Seq A exon
GTATGCCGTTTCTCCTCCATGACGTCATTAGCAAGCACATTACAGTGTGTGCGGATGTCCGCATTTGTGAACAGAGAACACACTGCAGTTGTAGAAGCACTTGACTTAGCTTCTTCTCCAGTGACCCAAGGGATAGAATATAGAAGCAAGGAGTACCCATACTGAGGCAGAAACATGAAACCATGAGGTGGATATTACCCTTTATCTATGCGGTTATACTGGTGAGGAACCACAGCCAGGGAGCAGCTCTGTGATTTGCTGAGAGGAAATCACTGTGGTGGCCAGAGGCTAAGCTTCTGTATCAGGTACGTTTGGCTCAGGAACCTGATCTTGACTAGCCCAGCCTGCTTGCCCACTCTATGGTCGTTGAGCTGTTTTCATTTCAGGTCTGGTTTTTATAGGACCCTGTTTCTCATCGTGGTGAGATGTCAAGAACATTAAGCAACTGTTAATACAACCAGAATTATTAATGTATTGGTCAGTTATTCATTCATTCAGCAATTGTAAGTTCACACCATGGAATCAAGAGTTAAGGGAAAACAGAAAATTTTAACGATTAGTTTAGCTATTTGCATCAACTTAGGCAGGAAGTTCCCTATTGTCCAGCGACTTGGTAAAGGAGACAGGATTTGAGACAAAGCCCTCCCTTGTAGGCTTTTCAAACCTTTGGGGGATATAGCATGAATATATACAGAAATAACTTTTAATGGCTGAGGAAGGAAGTAGACAATTGTTAAAAAGCTGTGCGTAAATACCAGGTGGTCACCCTGTCATTTAGCCAGCTATGGATGGGGTGAAAGGAGCCAGGCTGAGCTTGCAATCCAAAGCGCTTGATCTTCACACTTCTGTTCTCCCCTGTGAAAGTGCACTGCTTAAACTATTCTCAGCTACTTCTATTTGTAGGTGAGTTTTTCAGACCGGCAGAAAACACAGGATGCTGGAAAATGCCACAGCATGTTACCTGACAAGGCAGGTCTCAGCTGTTAGCATCTAAAGGCTACATTTAAATACAAGCCGCCTGTTGATGTTAAGTGGCGGCCTTTTGTTGTGGTGGATGCTGTAGAAGGAAGAGCTGCTCTCAGAGATCACAAGCTGTCTCTGTCCTAGTGTGAAAGGGGTGAATTTGAGGCAGCAGCCTGGGGTTTCCCTATGCAAATGGGGGGAGCTTACTTCCCTTTCACCTTTGCCAGCTTTGACCTTTTAATGGAATGCAGGCTGTTCTCTAAGAGTTTAAAGCAGTTGGGGTGAGGAGCAGCCCAAGGCAAAAGTGCACACTTCTCCGAGGCCCAGGGAGGAATCCTACCATCTCCACCTTGAGGATACAGTTGGTGGATGGATGGATGGATGGATGGATGGATGGTCCTTGTGCCTTTCCCCGTGGCGGTGGCACCATCAGCATGCCCAGCTTTATAGCTAGTAGTGTCTGTCCACAGTGCTAGGCAGCTGATGAGTTATCAGAAAGCCTTTCACTTTATCAATAGTGGTGATGGTGCTGTGTGATGGAGTTGCAATCTCCTGGCCACGGCCCAGGCACTGTGTCTCTGGCCTACACCACATCTTCATTTTATTCTAAAATTTCTCCCATCATTTGAGATAAGCCATCTGAGGCCTAAAGAGAGGGATGGGGCATCTTGTATTTGTGATGGCAGCTATGAAGTAGAAGAGGCAGGATTTGAACCTGTGTCCACCTGGATGTTGTTCCTACTAGCACTGTCCCAACATGTGTCAGATGGACCCTTCACCTCCGTGCACAGTGGACAGAATACACCAGCTCTGCACCTGAGAATTCCTCCGTAGAGCTGACCAATTATTGATTGAAAACCTGTGTTAGAAATAAAGCAGAGACAAAGCCTGTGGCTGTGCTGAAAAGACTTCTGTCTCACTGTTCTTTCTTTTTTTTTTAAAGATTTATTTTATTAATATATGTAAGTACACTGTAGCTGTCTTCAGACACTCCAGAAGAGGGAGTCAGATCTTGTTACAGATGGTTGTGAGCCACCATGTGGTTGCTGGGATTTGAACTTTGGACCTTCGGAAGAGCAGTCGGGTGCTCTTACCCACTGAGCCATCTCACCAGCCCCTCACTGTTATTTCTAAACCAGTGCTTCTCAAACTGTGGGTGGTAGCCCCTTTGGGGGTTGAATGGCCATTTCACAGGGATCACCCAAGACCATCAGAAAACACAGATACTTACATTATAGATTGTAACAGGAGCAAAATTACAGTTTTGAAGTAGCATCAACAATAATTTTGTGGTTAGGGGTCACCACAGCATGAGCAACTGTATTCAGAGGTCACAGCATCAGGAAAGCTGAGGACCACCGACCTAGCCAGTAACACTTAATACCTCTTTAGGGAGAATGTTCTTTGTGTTGTTACTGTAAATAATCTAGACATGGCTTAAGGTGTGTGGGAAAATGTGTGTTGGTTCTGTGCAGACAGTGGCTTATTATAAACAAGGGACCTGAGCATTTGGGGTGCTGGTTTCCATGAGCGGTCCTGGAACCCATTCCCCTACCCCACCCCAAGAAGCCCCTGTATGAAATGGTGCAGATGAGGAAGTGGAGGAAGGCTATAGGGGCTTAGGTGGGTCTCCAGCCTATTCATCAGTGAGACCCCGCCCAGCTCACCATCTCTCTGTTTGTTTGTTTGTTTGTTTGTTTGTTTGTTTTTAGGGTTGTTTTGTTTTCCGAGATAAGGTTTCTCTGTCTGTTCCAGGGTGTCCTGGAACAAGCTCCATAGATCAGGCTGGCCTTGAACTCAGAGATACACAAGCCTCTGCCTCCCAAGTGCTGGGAATAAAGGTGTGCACCCCCACTGCCAGGCCCCACTGAGTCATTGTATGCTCTCACAGCTCTTCAGGGCCCCGTGTATTATTTTAATTATCATTGTAGAACTACACTGTAATTACAGTAGCAGGTACCTGACGGTCACGTGTACACACCTCACAGTCTGTGCTCCCTTCACACAG
Seq C2 exon
GTTCGACTTCATCTATGACCTCTTTGAACACGTCTCCAGCCGCAACAACCAGGACACCTTGAAATGCGGAAGCAAACACCGGCGGCCCACTGTCAGCTCGCAGTTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000022272-Myo10:NM_019472:17
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.227
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0006316=Myosin_head=FE(4.1=100)

							
A:
NA

							
C2:
PF0006316=Myosin_head=FE(5.4=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000106087





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000106087f1215A, ENSMUSP00000118280, ENSMUSP00000123057
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr5:16758227-16761463 
LOW PSI
HsaINT0108164
(MYO10)
Human
(hg19)
chr5:16758336-16761572 
LOW PSI
HsaINT0108164
(MYO10)
Rat
(rn6)
chr2:78000936-78003740 
LOW PSI
RnoINT0096746
(Myo10)
Cow
(bosTau6)
chr20:56463740-56466498 
LOW PSI
BtaINT0097628
(MYO10)
Chicken
(galGal4)
chr2:75576738-75578094 
ALTERNATIVE
GgaINT0096737
(MYO10)
Chicken
(galGal3)
chr2:77282633-77283989 
LOW PSI
GgaINT0096737
(MYO10)
Zebrafish
(danRer10)
chr2:42792083-42792315 
LOW PSI
DreINT0100265
(myo10)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"