Special

MmuINT0104629 @ mm9

Intron Retention

Gene
ENSMUSG00000024388 | Myo7b
Description
myosin VIIB [Source:MGI Symbol;Acc:MGI:107709]
Coordinates
chr18:32169706-32173099:-
Coord C1 exon
chr18:32172915-32173099
Coord A exon
chr18:32169828-32172914
Coord C2 exon
chr18:32169706-32169827
Length
3087 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
TTCCCTGAACTCTCCTGCAGTGG
3' ss Score
7.73
Exon sequences
Seq C1 exon
ACCTACACAGGCTCCATCCTGGTGGCTGTGAACCCATTCCAGATGCTGCCCCTGTACACCCTGGAGCAGGTACAAATCTACTACAGCCGCCACATGGGCGAGCTGCCTCCCCACATCTTCGCCATTGCCAACAGCTGCTACTTCAACATGAAGAAGAACAAGAGGGACCAGTGCTGTATCATCAG
Seq A exon
GTGAGGCTCAGACCTCATTTCTGGGGCAGATGGTCAGCTACTGCCTTTAAGCCCCAAAGGATCCCAGAAAGAAAGAATCACTCCTCTCCTTAAGGTTCTCACAGGCTCTCTTCCTAACCAGAGGTCTTAGCAAACGTTTGCTCAGAACTGCTCCTACTGCCCTGCTCCCAATGACATGTCCCTCACACCTCAAGAGCATGTCCTCCACACCCCAAGGACATGTTTCCCACACCCTGACGACATGTTTCTTGAAGACACATCCTCCATATCCTGAGGTCTGTAAGGGCTAGGAGGGACAAGTGCCCTCTAACCCCAAGCATGGCTCTGCTTCCCTGCCTGCCTGATCCTGGCCACCTTGTACACAGACCTTCTTCCTGCTGAGGAAAAAAAAAAAAAGGAGGAGCAAGGACTTGGTTCCTGAGTCCCTAATTTGGAGTTGTAATCGTCATTCACTTATGCATGAGTTCATTCACTCATTCATTCATTCATTCAAGATCTTTCTATACCCATGCTAGAGATGTAGCTGGGTTGCTAGTGTGCTTGCCTAGCAATGGGTTCTATCCGCAGCACCACATGAACCAGGTGCAGTTGTGCACACCCGTAATCCTAGCACTCAGAAGGTGGGGACAGGAAGAGCAGAAATTCAAGTTCATCCTTGGATAGATAGCAAGATTTAGGCTGACCTGTGGTACATGAAATACTGTCTCAAAAATAAAAATAAGTAATAAACAAAAAGATCTTATCGTCCCTCCTTATCCTAACACAGGAAACAGCAACAGGTGAAAGAGACTCCAACTTCTGCCCCCAGGCTCATGTCACAGAACAGTAGACTGGCAGGCAGGTGCTAAGAACATAAGGGATGTAGAACAGGGAAGAGAAATAACAAGCAAGGGATGCTGCCTCTCCAAACAGGGGCACCTGAATGGCATCCTAGCATAAGTGACATTTCATGCCTTTAGTCAGCCTCGGAACTGGGCTCTTACCTTAGTGTTACGGAACCTCCAATTGAAGAGGTCGTGGTTCGAACCCAGTGATGTTACAGGTGCGGATCTAAGCCCCATGTTCACCTGATGAAGTTTCTAGGCTGTTGGGTCCCAGGTCAGAACTAGAAATAGAGATTGTTTTTTAAAGAAAGGAAATGCACTTCCAAGAGTGGGAGTTGGCACGAAAGCTGGGGACAAACATGTGCTCTAAGAATGCTGGGTCACAAACCACAGAACCGCAGTCAAGCAAGTACTTCAGCCCTGGGCATGAGCTCACTGCACTGAGGCGCGTGCCTCTAGGACCAGCTACTGGGGGGGGGGGGGTGTGAGGTAGAAGGCTCTCTTGAGGTCATGAGCTCGAGATTAGCTTAAGCAATATAGTGACCCTCTGTCCTCCTCTTCCTCCCCCTCCTCTCCTCCTCCTCCTCCCCCTCCTTTCTCCTTCCTCCTCCTCCTTTCTCCTCCTTCTGTCTCCCTTTTCCTCCTCCTTTCTTCCTGCTCCCCCTTTCTTTTTCTTTTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTTTTTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTTTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTTCTTCTTTCTTCTTCTTCTCCTCCTCCTCCTCCTCCTCCTCCTCTTCCTTCTCCTTCTCTTTCCTCCCCTCCTCCTTGGTTTTCAAGATATGGTTTCTTTATGTAGCCTTGACTGTCCTGAAACTTGCCCTGTAGACCAGGTTGGCCCCAAACTCAGAGGTCTGCCTTCCTCAACCTCCTGAATTAAAGGTGTGGGCCAACATTGTTCAGCCAGTCTTGTGTGCGTGCGTGCGTGCGTGCGTGCGTGCGTGCGTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGCAATTTTGGTGATGTTTATTTTGGTTTCATTTCGGGACTAGGTCTTATTATGTTTTTGAGAGCTATGTCTCTCACAGCTCTGGCTGGTTTGGAACTTGCTATGTAGAACAGGCTGGACTTGAACTCTTGGAGATCACCCTGTCTGCCTCCCGAGAGCAAGAATTAAAGGTGCTTTAAGAATTAGGTGCAGCATGCCCAGCTCAACTTGACCTTGGAGTGAACATTGAAGCCACTTAGCAGCTGGCTCTCCAGGACAGTAAGCAAGTAGCCAACAGAGCAGTAAACAAGGAAAGGACTGGCAGGTTCTTCACAGTGGGAATGACACAGAGGCAGGGTATGCGGCAGCCGCTCACACTGCAGCTCAGTCGGGAAGCTGAGAGATGAAGGCTCGTGCTAAGCTTGACTGTACCTTTTTATTCTGTCCAGGACCCCAGCCTGTGGAAATGTGCCGACCATATTTAGGGTGTGCCTTCCCAGTTCAAGTAACCCAATCTAGATAATCTCACAGACACATCCAGAGGCTTACCTCTTTGGTGACTCCAGAGCCTGCCGAGCTGACAATCAATAGTAAACATTCCAGCTTCTACACAGATTCTGATTGGGTGAAGCTAAGGGAACCTGGGATGCTAGAGTTCTGTCCAGATACAGATAACACTGGCCCAGGAGCCACACTTTCATCAGAAAGACACTGAGTCACCTTTCCTGTTCTGACAGGTAGCCCAGGGATAACCCAGATCATACTGTGCCAAGAGTCTTTCAGCCTAGCAGGAAAGAAAAGACAATGCAATAATTTCTACCAGGGATGCTCAACATTTTGACATTGTCTTCTCCAAATGTATTGAGCTACATTATAGTTATTCTGGAACACATCCAGACATGCCTGATCATAGATAGATAGTCCGAGATGCTCAGGGGACTTCAGAGCAAAGGCATTGTGGAATTTCTTCTTGGGAAAGTGTATTCATGTTAGCATGGCCCAGGGGACACAGTGGGTGGGAGCTGGGAGCACGGAGGTCATTTATAGAGAGTGGAGAAGCTCTAGATAGTGGTAAGTCTCTGTCTGAGGCCTCATTTCCCTGAACTCTCCTGCAG
Seq C2 exon
TGGCGAGTCTGGGGCCGGGAAGACCGAGACCACCAAGCTTATCCTTCAGTTCCTCGCCACGGTCAGTGGCCAGCATTCGTGGATCGAGCAACAGGTCCTGGAGGCCAACCCCATCCTGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024388-Myo7b:NM_032394:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0006316=Myosin_head=FE(8.9=100)

							
A:
NA

							
C2:
PF0006316=Myosin_head=FE(6.0=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000118046





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr2:127566828-127569788 
ALTERNATIVE
HsaINT1024320
(MYO7B)
Human
(hg19)
chr2:128324403-128327363 
HsaINT0108990
(MYO7B)
Rat
(rn6)
chr18:24800614-24801866 
LOW PSI
RnoINT0097455
(Myo7b)
Cow
(bosTau6)
chr2:4888508-4896784 
LOW PSI
BtaINT0098338
(MYO7B)
Chicken
(galGal4)
chr9:839513-840306 
ALTERNATIVE
GgaINT0031392
(MYO7B)
Chicken
(galGal3)
chr9:2273510-2274303 
LOW PSI
GgaINT0031392
(MYO7B)
Zebrafish
(danRer10)
chr6:28066259-28072426 
LOW PSI
DreINT0015023
(MYO7B (1 of 2))
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"