MmuINT0119676 @ mm10
Intron Retention
Gene
ENSMUSG00000030660 | Pik3c2a
Description
phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide [Source:MGI Symbol;Acc:MGI:1203729]
Coordinates
chr7:116364428-116368189:-
Coord C1 exon
chr7:116368044-116368189
Coord A exon
chr7:116364617-116368043
Coord C2 exon
chr7:116364428-116364616
Length
3427 bp
Sequences
Splice sites
5' ss Seq
TGGGTATGC
5' ss Score
6.57
3' ss Seq
TAATTCTATTATATATGCAGACT
3' ss Score
4.2
Exon sequences
Seq C1 exon
GTTGATTTTCCTTCTCCTGCGTTTGACATTATTTATACATCTCCTCAAATTGATAGAAACATTATACAGCAAGACAAGTTGGAAACACTGGAGAGTGATATAAAGGGGAAACTTCTGGATATTATTCACAGAGATTCATCATTTGG
Seq A exon
GTATGCTTTGTTTATTACTTTCTTGGGACTCTCCTGTGATGTAATACTAAGGTTAAAGCTTATATTATAGACCATGATTTAGAAGTTAAGTTGTCTTGATATGAAGAGGGCCACTTGGGACTGAGAGTAAAGAATGATCCCAACAGTGCCAATGAAAGACTGGCTACATACAAATCAGGGAAATGTATAAATCTTTTAGTATTTTTAATTATTTAGCCTTTAAAATTGTTTCTGTAACACGTGTCTGTGTGTGCCCATGTGGAGAGAGGCCTACCTGGGGTCTCTTTAACCCTCTTTTTTTTTTTTTTTTTTTTTGGAGACAGACTCTTACTGAACCTGGAGCTCGACTCTTGGCAAGGCTGGCTGGCCGCTGGCCACAGGACTTTAGAGATTCTCCCTGTCTCTTCATTCCCAATGCTGGGCATGCAGATGCACACTGCCACACCAAATTTATATGTTAATGCTAAAGATATGATCTCAGGTGCTAATGTTTGCATAGGAAGTAATTTTTCCACTGAGCCATTTACCCAGACTCATGTTTTACTGTATGTGAACATGTATGTGCATATAGAATATAGAAGTTAACATTAAATATCTTCCTTAGTCAATCACTCTCCACCTTATTTTTGAGGTAGGGTCTCTGACTGAATCTGGAGCTTGCCAGCAAGTTGAATAGACTGGCTGGCTATCAGGCCCTAAGATCTACTTGTCTCCACCTCTATTACCCAGATGCTTTAAAACAAAACAAAATACAACACATCAGTGCTGGGAATTGAATTCAAGTACTTATAATTGCATAGCAAACATTTTCCCAACTGAGCCATCTTCCAGTCCTTCTTGAATTATCAAAGGCAAACAGGCTGAGAAATATATTTCTAATATGTATCAGCTGATTAATTTGCTTAATCTATTTATGGGCTGACAAGGTGGTGCAGCAGATAAAAGTGCTTGCCAGTCAAGCCTGGCCACCTGAGTTAAATCCTGAAGCCCACATAAAGGTGAAAGGAAAGCACAGATTCCAAATGTTGTCATCTGACTGCCACACATGCTCTATGACATGCATGCCCAAGCACACGCTGTCCACACACACACACACACACACACACACACACACACACACACACACACACACACACATTTTTTAAAGGACATCTTTACGTTAATAAGATAAATAGCTAAGTAATAACAGAAAGTGGATGAACAAGGCAAGCTCTTAAAAATGAGATATAGGGGATGGGGGGCTGGAGAGATGGCTCAGTGGTAAAGAGCACCAACTGCTCTTCCAGAGGTCTATAATCATCATCCTATGAAGCTATATGTAACACACAAAGAAAATATACATAACACACAAAGAAAGAGAGAATTATTTTATTAGCCAGATATTTAAAGGCCACATTCCTTTTGGAGAGCAATTTGACAAATCTGTAGATGTTATATGTATACACTGCAACCCAGCAGTGCTGCTTCCTAGTATAAAGTAGAGAAAATGCTCATGTATTTCTGTATTGAAACACAAATGTTGTTTGTAATATTTATTTGCGTTGCCAACTGATGGTTGATGTCCATTGATGGGAAATTCAATTATCCAGATAGCAACGGTGAATATTTATAGCTGTATATATTAGTACGTGATACAGTAAATGGAGAAACTAAGCAGCAGATTAGGATGGTGACATCATCAACACAGAAAATAAAATCTAGAACACACCCATGTGGATACTTTTGTATGAATAGACCATCTCTGGAAGCGTAGCATGTTGTCCTGGTCCACCTCTCCCTTGGGGTAGTCAGGCCCTTGTGCACCAGGACTGGGTGGTGCAGGCAGGATCTTGGTCAACAGTGAGTTTGTGAACAAAGAACACACACCCAGGAACAGCTTTGGAGAACTAATTCAGTTTGTGGGTCGTGGGGGGTGGGTCAGGAATAAAGACTGTTTAAATTTTTTAGGGGTGTTAAGGGCTATCAAGATGAATATATATCATTGGCCATGGCTAGGTATGCCTCCTCTGCATGAGGAGGAATTCCAGGTGCTGCTGGACATGACCTTGTAAGAGGAAAGGCAATTTAACCTGGCTGCCAGCTTTGTGACCTCCCCTGGTGAGGCAAAGATTGGGGGCATAGGGCTATGTGGACCAGTACATGCGGGCCCAGGGCAGTAGGTGAGAGATCCTACTCCTTCAGATCTCAGGATAAGAATTCTGGGGTTTGAACATGCTTGACCCCACTCACAGCCTGCTTTCCCAGTCCCAAGGCTTCCTGACCTGGCAATACAGATGCTTGTCTATAGGAGAATTAGGAAGATTCCTGTCTTAGTTAAGGTTACTATTGCTGTAAAACACCATGACCAAAGCAACTTGGGAAGAAAGTGTTTATTTGGCTTACACTTACTTCCACATCACTGTTCCTCACTGAAAGAAGTCAAGGCAAGAGCTCAAACAGGACTGGAGCCTACAGGCAGGAGCTGATACAAAGACCATGGAGGACTGCTGCTTACTGCCTTGCTCCTCATGTCTTGCTGAGCTTGCCTTCTTATATATAGAAACTAGGACCACCAGCCCTGAGATGACACCACCCAGAGATTGTATGGGTCCTCCATCCTTTATCATTACTTAAGAAAATATATGGGCTTGTCTGCATTTTCAGTTAAAGTTCTATCCTCTCAGATAATTGTAGCTTGTATTAAGTTGACCTAAAACTAGCCAGCATAACTTGCATACTTCTTATCATATTTGTGGGCTTTTCCATACTGAATATGAGATTAATACATTTTACTTGAGTACTGTGTGCACAAAGATAAATGTGTGAGCCAGACATGCTATTGAACACCTGTAATCTCAACACAGGCAATAGAGGCAGGAGGAACAGGAGTTTGAATCCATCTCAAGCTGCATGGCAAGTTTGATGCCAGCCAGGGCTATATAAGATCCTGCCTCAAAAAGAATGAGGAACAACAGTGAAATATTTCATGAACATGTCATTGAACTTAACTCAGAGAATGTCTCCAAAATACTTTTTTTCCCCATTTTGACTATTTTTCAATTCAACTGTATGCTTCCCTAAAAACAGACCGCAGCAGCATTTGTTTTCCCTGTTGCACTTGATTTTACTTGTGTGGATGGAATTCTTGCTGCCTTGCAGGGTGAGCTCTGCTTATTTAACTCTGACTTTGTAGTGCTTGGCATCTTGTTGGAATTTCCCTTTATTTTAACAAATATGGCACTTTGTCAAGGCAGAACGATTTTCATCTCCAAATAAAGGTAGATTAGTGATGTTTGCTATGCATTGAATATTCCTATTTGATATTAATATTAGTACTATCAAGAAGTGACTGTCACAAGTGAATATATTTCTTCTTTGAATTTTTAATTATTGAGATAACTATATCATAATTCTACTGGGAAGTAATTTAATTCTATTATATATGCAG
Seq C2 exon
ACTTTCTAAAGAAGATAAGGTCTTTTTGTGGGAAAACCGCTATTATTGCCTAAAACATCCAAATTGTCTTCCGAAGATATTAGCAAGTGCTCCAAACTGGAAGTGGGCTAATCTTGCCAAAACTTACTCATTGCTGCATCAGTGGCCGCCATTGTGCCCACTAGCTGCATTGGAGCTCCTTGATGCAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030660:ENSMUST00000170430:15
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0079219=PI3K_C2=PD(3.5=10.2),PF0061315=PI3Ka=PU(12.5=46.9)
A:
NA
C2:
PF0061315=PI3Ka=FE(34.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types