Special

MmuINT0127528 @ mm9

Intron Retention

Gene
ENSMUSG00000049013 | Prss48
Description
protease, serine, 48 [Source:MGI Symbol;Acc:MGI:2685865]
Coordinates
chr3:85804304-85804852:-
Coord C1 exon
chr3:85804808-85804852
Coord A exon
chr3:85804467-85804807
Coord C2 exon
chr3:85804304-85804466
Length
341 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
3' ss Seq
CCCTGCTCTTCTTTGTCTAGTAT
3' ss Score
7.93
Exon sequences
Seq C1 exon
GAGCTTTCCAGGGCTCTTTTACCAAAAAGAAAAACTTGCAATCAG
Seq A exon
GTGAGTATCCTCACGCTGGATCTGAACCTGGACTTGTGGGGCTAGAGGCATGGCTTGGTGGTTAGGATCACTGGCTGCTCTTCCAAAGGTTCCGAGTTCAATTCCCAGCCCCCATATGGTGGCTTACAACTGTAGTTCCATGAGATGCCCTCTTCTGGTATGCAGTCAAAACATACAGATAAAAGTATCTAAATAAAGAGTCTTTTAAAAAATGGAATTGGGAAGGGTAAGGAGTCTTAGGGAGGGCTTAGATCCTAGAAAAGGATGAGATGGGAGTTTGGGGACAATAAGAAAATGGCGGAACTTCAATCTGCACAGTTCCCCTGCTCTTCTTTGTCTAG
Seq C2 exon
TATGTGGACGACCTGTACACACTGGACGCATTGTGGGTGGCCAAGATGCTGCTTTGGGGCGCTGGCCCTGGCAGGTGAGCCTGCGTTTTGACTACACCCATTCTTGTGGAGGTTCTCTCATCAGTGACCACTGGGTGCTGACGGCAGCACACTGCATAAAAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049013-Prss48:NM_001001650:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NA

							
C2:
PF0008921=Trypsin=PU(19.0=80.0)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000051199





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr4:151277225-151279795 
HIGH PSI
HsaINT1028238
(PRSS48)
Human
(hg19)
chr4:152200767-152200947 
HsaINT0133013
Rat
(rn6)
chr2:185301164-185301461 
RnoINT0118787
(Prss48)
Cow
(bosTau6)
chr17:6523446-6523623 
BtaINT0118777
(PRSS48)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
chr6:39089257-39089599 
LOW PSI
DreINT0179487
(zgc:162180)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GCTTTCCAGGGCTCTTTTACCA

				
R: 
GTCAGCACCCAGTGGTCACT

				
Band lengths: 
185-526

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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