Special

MmuINT0130393 @ mm9

Intron Retention

Gene
ENSMUSG00000026878 | Rab14
Description
RAB14, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1915615]
Coordinates
chr2:35039264-35042260:-
Coord C1 exon
chr2:35042194-35042260
Coord A exon
chr2:35039352-35042193
Coord C2 exon
chr2:35039264-35039351
Length
2842 bp
Sequences
Splice sites
5' ss Seq
ACTGTAAGT
5' ss Score
8.59
3' ss Seq
TTCTTTTGTTCACGAATTAGGTA
3' ss Score
5.47
Exon sequences
Seq C1 exon
AAGAAGTACATATAACCACTTAAGCAGCTGGTTGACAGACGCAAGGAATCTCACCAATCCAAACACT
Seq A exon
GTAAGTCAACACTTAACTGTATAGAGATTTAAAATCAGCTAACCCAAACAGGCTGGCCTTGTACTGGTGAGATATTGTTATTTGGGTGCTAAGATTAAGAGACCATTCCCTCATTCTCTCACTCACTCATTTATTCATTGCATTCAGATTTTCTTTAATGCTAGAGATGCAGGCCTCATTTATGCGAGGCAGATGATCTGCCATGAAGCTACATCCCCAGCCCCAAGTATTTTTATTATACTTTTTATGTTTGGATTTGAAAACAAAAACAAAAAGCTATGAATGAGGTGGTGCTATCAGTTGGAGTTATTATAATCTGAAATTATAAATTTAAAACACTTCTAGATTAAGTTTGTAAAATATTACCATTAGAGGAAACTGGGCAAAACTGTGCAAGGGCTCTTTTTGGTTTTTTACAGTTGCATGTGAATTTGTAATTATCTCAATAAAATGTCAACTAAAAGTAAGTATTCTATATACTTTAAGTAATTAACTTCTTAGCAAGACAGAAAAGATACTGAGCTATTGAAGGACAGCTACCATGCTAGATTTCACAGTATGCAAAGATAAACATGTTTCTGGTCCTCAGTGGGTTATTGTCTAGCAGAGAGAACCTTCAGGTTTACTGAGAAGCCATAAAACCACCTGAATGATGAATTAGAAATGTGAATGGTTCAGTGGTGGAGAGCACAGTCGAGCAGGGCCTTCTGGTATCCTGGAGGGTGTTGCAAGAACAGTGTTTCACTTAGCTTTGTACCTCCTGCACTTGGTAAGAGATCTGTTTTGCTAGTGTAGAGCCTAGAGCTTTCATTTTCATTTATACTAAACTCGGCTGTTGCTATGCATAGAGACCTATGGATAAATGTTCATAGCAGCTTTATTTGTGATAACTAAAAACGGAAATCAGTCCAGCTACCACAGATATGTGAACAGCAACAGTTTGGTTGCAATTCCCACTTCAGTGACCTGGTATTCAGCCACACTGAAGAAGCAATTAGGGTAACAGCATCAGCTGATAAATCTGAAGAGAATTTTGCTGAGTTTAAAAAATCTAAAAGGCTTACATATTCTATGATTCTATTGACATATTTCAAAATGACAGTATTGTAGATAGATAAAGAACAAACTAGTGATGGCCAAGGGTTGGTTAGTGACAGGTTAGGTAGTTGATAGAACTGGGAAAAAACAGCCAGAGCAGTTTCTTGGTGATGATGTTGATAATTCTGTGCCCAGATTGAGGTGACAGCCAGAGTCTATTCTAACACTGCACAGAGCCACATGTGGGTACAGCCACATACACTTTTGAAAAACAAACAAACAAAAAACACTGGTATCTTAGGGCAGTAATTGTACCAGTGTTAGTTTCTCGTTTTGACAGTATAATGTAGCCCTGTGAGTTACTAAAAAATTTTGAAAATGTTTTTTGAAGCACACTTTATTTATATTACTATGTTTCCTATGAAATTGCCTTTTGTTTTTATGGGGAAAGTATGTATTCTTCATTTTTGTTAATGTTTTGTGCCACTTTGTTACAAGACTACCTCTTGAGGGAGGGAGGTGGGCAATGAAGATTGGAGATTGATATGTAGTTGGGAAAGAGAAAATACTTCTTTTTGAAGAGAGTTGTGGTAGAGTGGAGTGTTGGAGATTAAAACCATAGCTGAGTGCCTGCTAGGCAAATGCTTGCCCATACTGAAGATAGTATTTCTTGATTTGAATGGGTTTGATCTTTTTGTTAAGTGCCATTATTTTATTGTTCAAATGACTATGAACATTATTTTCCCTTGTCAGTAGTCACTTGCACTTTGAAGAATGATTTTATTATTGCTGCTGTTGTTGTTATTGTTGTTGTTATTATACCCATGTAACTTACTTGGAAATAATTGATTAGTTCACTGGACCCAAATATTTGAAAGTGGAAGAGACAAGTACAAGTACTAATTTTATATGGAAAAAAAAAGTTGGGAAGCACTTTTTTGTTGAAATCATTGATTCCTAACCTCTGTATCTGGTTAAAGGGGGCAGGAAGTAGAAGAGGGGCTGATATCTTCCCCCTTTGTGCTTTAAATAACAAACAAAACCCCTTTGTTTTCTACGGCTACCTTTAGTCTTTTAACAATTTTACTCGAGTAGGTAACTCCAAAGTAGATGACAGAGTGTGGTATTTGTTCCAGGATTTGAACCTATTGCGTATTTATCCCATCCTCAGCTTCTTTCACAGACACACGCATTGCTGATAAGTTGATAGAAATTTACACCTCTCCTGGGATAGTTTGTCTTTAGGTCACAGTTTGCATTCTCTAAGGTTCTAATGCCCTCTTTGCTAACTCTGTCTTGAATTTAAGGGGAAGGTAATTACTGTTACCCTGAATGAATTAAACTAGTGGTTTTCAAGTTTCCTCAAGGTCCCAGAATCTTTTGAGAACTGAAAGCTATAAGCCTTCTCCAGGGAGTGTTCATGGTAACAGCACTTTGCACTTAATTTTAGGGCCTTCTTATTAATTTTGCTTATTTTTTTTTGGCCTAGACCAGATATGAACAAATTGGCTTGTGAGCCATATTCACCTAATGAATGACTTTTCTATTTTTAAGAGATTTGTGACAACAATAAAAATAATATTCAGCAAGACTTGTGTGGGGCCCACAAATCTGAAATATGCCTTCTCTTCCTTACAGTCATTTTTCAGAACCTGAGCCAGCTTGTTGTGAAAGTTCTGCTCAGTGTTCTTGCCTTATGCTGTGTAGTCCAGGGCTCATCTTTTTTTCTGTCAAGGCTTTTGTATTTGAGAATTTTCATAGGTATTTTTGTTCTAAGATATCTTTTCTTTTGTTCACGAATTAG
Seq C2 exon
GTAATAATTCTCATAGGAAATAAAGCAGACTTGGAAGCACAGAGAGATGTTACCTATGAAGAAGCCAAACAGTTTGCTGAGGAAAACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026878-Rab14:NM_026697:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.020
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0007117=Ras=FE(13.6=100)

							
A:
NA

							
C2:
PF0007117=Ras=FE(17.9=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000028238





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000028238f2020A, ENSMUSP00000108648, ENSMUSP00000125976
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr9:121183399-121186952 
ALTERNATIVE
HsaINT0135973
(RAB14)
Human
(hg19)
chr9:123945677-123949230 
ALTERNATIVE
HsaINT0135973
(RAB14)
Rat
(rn6)
chr3:14376870-14379835 
ALTERNATIVE
RnoINT0123029
(Rab14)
Cow
(bosTau6)
chr8:112503978-112506848 
ALTERNATIVE
BtaINT0121219
(RAB14)
Chicken
(galGal4)
chr17:8380253-8381114 
ALTERNATIVE
GgaINT0125654
(RAB14)
Chicken
(galGal3)
chr17:9084909-9085770 
ALTERNATIVE
GgaINT0125654
(RAB14_CHICK)
Zebrafish
(danRer10)
chr5:71390495-71391644 
LOW PSI
DreINT0123370
(rab14l)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"