Special

MmuINT0132034 @ mm9

Intron Retention

Gene
ENSMUSG00000070565 | Rasal2
Description
RAS protein activator like 2 [Source:MGI Symbol;Acc:MGI:2443881]
Coordinates
chr1:159091256-159094070:-
Coord C1 exon
chr1:159093834-159094070
Coord A exon
chr1:159091458-159093833
Coord C2 exon
chr1:159091256-159091457
Length
2376 bp
Sequences
Splice sites
5' ss Seq
CAAGTAAGG
5' ss Score
7.66
3' ss Seq
TATCTTCTCACCTAACTCAGGTT
3' ss Score
6.6
Exon sequences
Seq C1 exon
TGTCTTCCCGCGTGAGTTGAAAGAAGTGTTTGCATCATGGAAGCAGCAGTGCCTGAACCGAGGCAAGCAAGACATCAGTGAGCGGCTCATCAGTGCCTCATTGTTTCTCCGTTTTCTTTGCCCAGCCATTATGTCTCCCAGTCTTTTCAACCTGATGCAGGAATATCCTGATGACCGCACATCTCGGACACTAACTCTTATTGCCAAGGTCATTCAGAACCTGGCCAACTTTGCCAA
Seq A exon
GTAAGGGAAACTACTAGCCTAACCCTTTAAAACATCTGGTCTAAAATAATGCATGAGCATTTGCATGAGGCTAGGGAGCTGCAGACCTACGCTTACTAGATTTTTATTGCATTGTCAATAAAATTTTTAAAAGGGAAACAAATATTAAGCTCTCGTACAAACATTTATTGAAGTATTTATAACATTTAAAGTAATTTATATAAAAATATCTAATAATGTGAAAATGCTGATATAACTAGATTAAAATACTAATTAAAAGATAGAATGTCAAATGATACATATACTATCATTTTAGCAATATGAAAAAATAACACAGGTGTGAGAGTATTGGAAATAGACTAGTAATATGCTTATATCATATGTACAAGTGTTGTCAAAAGAGTCAACACTTGAAATTTAATTAATATCATAAGTTAGAGGTAGTATCTATAATTTAGTTTAAAATGGTTCTATATAATAAAAAAAATGTATACATATCTATAGAGATTGAAAACAAACCTACCCCCTCCCCAAAAGTTAACAGTTGGTTGATATAGATGAAAAGTATATGGGTGTTTATTATTCTTTCAACTTTTCTATAGGCTTAGAAAACCAATAACAGTGGCTCATACCTTCAATCCCTCTACTCAGGAGGTAGAAACAAGTGTGTCTCTGTTAGTCTAAGGCCATGAGACTGTCTCTAAAAATAGGAAGGAAGGAGAGGGTGGGGTGGGGGAGGGAAGAAAAGGAATAGACCAAAAAAAGAACCAGGAATGAGTTCACACATTATAAACTTGATTACAGATATATATGTATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTATGTAGTATGTATGTATTGTGTTCAGACACACAAGCTTCTACCAACAGTATGTGGAAGAAAAACTGTCAGCAAAGCAGATTGTCTTCAAATATATTATTTTGTAGTTTTTAATTTTTTATGTATTTTTACATGTATGGGTGTTTTGCTTGCATGTATGTTTGTGTACCACATGAATGTCTGGTGCCTGAAGAAGGCATTGGATCTTCTAGGACTGGAGTAAGAGAGCATTGTGAACTACTGTGTATATGCTGGGAATGGAACCTAGGTCCTCTAGGAGAGCAGCTAGTGCTCTTAATTTCTGAACCATCCCTCCAGCCCTCTAATAGACTATTTTTTCATTCACTGTTTGAATTTTATGAACCTCATAGCTAGGTCAAGACAGAAAGATTTGCCCATATTTGAGCTATTTCTTATAAAATTATTTTTAGGTTATATTGGAACAGGTTTTATATAAACTAGGATAGATAAAATCTAGAAGGACAGAAATTTCTTCTCTGATGAAATAAAGAGCATGCGCAGAGACTTAGAAAAAAAAACACTCCCGGGGGCTGTAGAGATGGCTCAGCAGTTAAAAGCACTGACTGCTCTTCCAGAGGACCTGAGTTCAATTTCCAGCAACCACATGGTGGCTCACAACCATCTGTAATGAGATCTAACGCCCTTTTCTGGTGTATCTGAAGACAGCTACAGTGTACTTATATATAATAAATAAATCTCTAAAGAAAAGAAAAGGCCCACTCCCATACAATCTCCCCTTGTGCAAGAATTGCAATCCATGGTTTTAATTACTCATGATCAACTCTGGTCCAAAAATATTAAATGGGACATTCTAGAAACACACCGTTCTGAGGAGCAAACATTCCATGAAGTCTAGCTCAGTTCAACCCAGAATCTCAATCATCCATCTACTCTATATATCCATGAAGTAGGAGCCACCTACCTGTTACTACTAGGCTCCTAGTTTTTATGTTAACTAATGAAGTATCATAATACTTATGTTCAAATAACCTTTTATTACTTAGTAATAGCTCCCCAAGAGCAGAATAGTTATGCTGGCAGTTTGGATGTGCTAAAGAAAAATTATAAACTCATTTTAAGGTTGGTTTTTTTGGGTTTTGTTTTGTTTTGTTTTTAATGAGTGCATGTATAGGGCAAAACAGAATTCCATGATACCTGCAGTTTCAGGCATCACTTGGAGGTCTTCAATATGAACCATGGGTAAAGAAGAGACTACTATGGAATATATTTGGAAACTGAAATTAGTTAAATTGACAGTCATCTTGATGGGCATTTGGTAGATAACTAGGGGCTGTATTATATGAGAATTTTGAAGACCCAAAAAAAGGCATTTTGTTTCTCCTCTTGAGATTTTTCAACATGAATTAAAGTAATACTAAAAAAGAATGTTGTAGCATTTACCACTTAAAGTAACAAAATCCTCATCACAAATTAAAAGAAATAATACCCATTTGTAAGTCAACTCAAAATATTAATGTCTTTTCTTGATGTGTGTTCTTTCTTATCTTCTCACCTAACTCAG
Seq C2 exon
GTTTGGTAACAAAGAGGAGTACATGGCATTCATGAATGATTTTTTAGAACATGAATGGGGTGGAATGAAGCGGTTCCTTTTGGAGATCTCTAATCCTGACACCATCTCAAACACCCCAGGCTTCGATGGTTACATTGATTTGGGCAGAGAGCTGTCAGTTTTGCATTCCTTACTATGGGAAGTAGTTTCCCAACTTGATAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000070565-Rasal2:NM_177644:11
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0061614=RasGAP=PD(44.2=95.0)

							
A:
NA

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000077423f5413A





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000077423, ENSMUSP00000114964, ENSMUSP00000117176
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr1:178452653-178454446 
ALTERNATIVE
HsaINT0137712
(RASAL2)
Human
(hg19)
chr1:178421788-178423581 
ALTERNATIVE
HsaINT0137712
(RASAL2)
Rat
(rn6)
chr13:74799426-74802979 
Cow
(bosTau6)
chr16:61289823-61291501 
LOW PSI
BtaINT0122614
(RASAL2)
Chicken
(galGal4)
chr8:6444579-6445245 
ALTERNATIVE
GgaINT0038835
(RASAL2)
Chicken
(galGal3)
chr8:6770273-6770939 
ALTERNATIVE
GgaINT0038835
(RASAL2)
Zebrafish
(danRer10)
chr2:35856932-35857139 
LOW PSI
DreINT0124793
(rasal2)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"