MmuINT0139642 @ mm10
Intron Retention
Gene
ENSMUSG00000075318 | Scn2a
Description
sodium channel, voltage-gated, type II, alpha [Source:MGI Symbol;Acc:MGI:98248]
Coordinates
chr2:65701717-65707360:+
Coord C1 exon
chr2:65701717-65702064
Coord A exon
chr2:65702065-65707227
Coord C2 exon
chr2:65707228-65707360
Length
5163 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGG
5' ss Score
8.41
3' ss Seq
CTGGAATTTTGGTATTTCAGGGC
3' ss Score
4.94
Exon sequences
Seq C1 exon
TCTCTCTTGAGCATCCGAGGCTCCCTTTTTTCTCCGAGACGCAACAGTAGAGCAAGCCTTTTCAGCTTCAAAGGTCGGGTGAAGGATATTGGTTCTGAAAATGACTTTGCGGACGATGAACACAGCACGTTTGAGGACAACGACAGCAGGAGAGACTCTCTATTTGTACCACACAGACATGGAGAAAGGCGTCCCAGCAACGTTAGCCAGGCCAGCCGTGCCTCCCGGGGGATACCCACTCTACCCATGAATGGGAAGATGCACAGTGCAGTGGACTGCAACGGTGTGGTCTCCCTAGTTGGAGGCCCTTCTGCTCTCACATCTCCTGTGGGGCAGCTACTACCAGAG
Seq A exon
GTGAGGACCATTAAAGCTGCATCTGAGAGCACAGAAAAAGAAAGGACATGGGTACAATCAGGGATGTGGGTTTTGATTTACACAGATGATAATTTTCCTGCATCTTTTATTCCCAGGCCAAGAGGTGGCTGGTTTTATCAAGCTATGAACTTATCTCCTTAAAAAAAAAAAAAAAAACAAAAAAAACAAAAAAAACCTTCAACACAACTCTACAAATTAATATCATACAATGAGTTTCATAGGCATATTTGTTCATTATTATTCCTACAGTTTGGACTTTAATGTAAAAGTCAAATCACATCTTTGTCATGCAAGCATGTAACTATCATCATCATCGTTGTTGTTGTTATTATTATTATATTTTTTCGAAACAAGGTTTCTCTATGTAGCTCTGGCTATACTAAAACTTCCTTTGAAGACCAGGCTATCCTTAAACTCAGAGATTAACCTGCCTCTGCTTTCCAAGATATGGAATTAAAGGCCTGTGCCACCACACCTAGCAATATGATTAAATATTAAGAAATTAAAGAATATAAACATGAGCATGATTACATATACACATATAAAAGGACAGACAGACAGACAGACACACAGACACACATACACACATACACACACACACACACACACACACACACACACACACACACACACGTATATATGCATTTCAAAGGTTTTTCTATCCTGTCCCTTTAAAACAACTTCACACCTCCACTTGCTGTCATGCTCACACTATCCCATCTAAATCCCTTACTTCACAGTTCTCCAGATTTTTCATAGTGTGCCTTGCCCCCAGTACCAACTCTAATGACCCAGCCACCCTTCATCAGCAAAGAGACTGCTTGAATAGCACAGGCTACAGTCCCATGTTTTCTTTTGGATTTCTATTTCTAATGGATTTAGCCTTCCATATTACTGCCATGAATTCTTCCTATATGCAAAGTCACCCCAAATTGAGCATATGGAAAAGATTTTCAACTTAATAATGTTTATCAGGATGTATCACTGATGGTCCCTTTATAAAGAGGGGCATTCCTCAAGTTGGCATTAAATGAAACATCACTTAACCTTTATAAAACACTTCAGCCATGTTGTCTGATCACATCACAGTTTCCCCAGCTGGGATAAAATCTCCTTTATATTATTACTCTTATATCATTTCTTTTTTTTTTTTTTTAAAGCAGACACATCCCTTACGGCCGTGTTATAATGGTCCAAATAGTTTTCAATTACTTCTTTTTTTTTTTAATTTTTTTAATTAGGTATTTTCCTCATTTACAATTCCAATGCTATCCCAAAGTCCCCCATACCCTCCCCCCACTCTCCTACCCACTCACTCCCCCTTTTTGGCCCTGGCGTTCCCCTGTACTGGGGCATATAAAGTTTGCAAGTCCAATGGGCCTCTCTTTTCAGTGATGGCCGGCTAGGCCATCTTTTGATACATATGCAGCTAGAGTCAAGAGCTCTGGGGTACTGGTTAGTTCATAATGTTGTTCCACCTATAGGGTTGCAGATCCCTTTAGCTCCTTGGGTATTTTCTCTAGCTCCTCCATTGGGGGCCCTGTGATCCATCCAATAGCTGACTGTGAGCATCCACTTATGTGTTTGCTAGGCCCCGGCATAGTCTCACTAGAGACAGCTATATCATACAAGAAGCCTACAGAACTTCAATTACTTCTTAGAGGAATGTCTTGCCCTGGAATATGACAACAGCGGCTGCTCACCACTGATTTCTTATGGCCTTTTCTCAGCTTTTCCTTCCAAGGAAATTTCCATGTATCCTGGAAAAATAGCAAGCCATGGAAGAGTAGAACTTTGTTGTGAAGCAGACAAGAAGAATGATAAGGAAATGTCACATGTTCTTAGAGAAATAATTTTAGCCAGTTATGTTCAACACATTTCCCAGAACACTGTGGGTTTATTTCATTGAACCCTCACAATTACCCATTATAATAGTTACTAGTTTATGCCCATTTTACAGAGGGACAATTGAGGCCTATACATGCTTAAACTAAGATCTGATCCCAGATGTGCTGTTTACAAGCCCTACTATACTCTATTCACAGTGAAATACAACATTCTGTTGGATTTTCTTAAATGGTAAAATCATTACCATTATAAGGTTAGGTCTTCTCACCGAGATCTGCCTGACCCAGCCTCCAGAGAACTTGGATCAAAGGTGTGCACCATCACTGCCTGGCTAAACCTTTTTCTTTCTGTTTGTCTTTCTATCTTTCTTTTGTTCTTTCTGTCTGGCTTTCTTTCTTTTTTCTTTCCTTAATCCGCAAAATCTAAACACAGTTTAATTAAAATACCAGAGACATATTAAAAAAAACAAATAAATCAATGCCTTAAAATGGCCCCAACCTAGTGTCTTAGTTAGGGTTTTACTGCTGTGAACAGACACCATGACCAAAGCTACTCTCATAAGGACAACATTTAATTGGGGCTGGCTTACATATTCAGAGGTTCAATCCATCATCATCGAGGAGGTAGCATGGCAGCATCCAGGCAGACAAGGTACAAGAGGCAATGAGAATTCTACATCTTCATCTGAAGTCTGCTAGCACAATACTGGCTTCCAGGCAGCTAGAATGAGAGTCTTGTAACCCACACCCACAGTGACACACCTACTCCAACAGAGCCACACCTTCTAATCTTACCACTCTCTGGGCCAAGGATATAAACCATCCCACTTAGGATATGAATGAGTTCACTGATAAAATGGAAACACTGACGAGGGAAGTTGAGGAAGACACCAGAAGCAGAGAGTTCCCATGCATGCAATGGCACGTGCTGTTCCACTGAGCTACTTCAATCCAGGTTCTGATAGATTGATGTAATACTGAAATATTGATGTATAGATAAAGAAAAAAAAAGTTTTTCTTAAGTCATGCTTCAAACTCTCTCAGGAGATTCTCAGAAATGGAATTTCCAAATTTTCTGGCTGTACCAGAGCTACTCGGAGTGAAACTTTGCAGCAGGATCCTGGAAATCTTTTTCTTATGAAACAGTTCACACGGTTCTTGAATACAGAAGTAGGTCCATCACTGCTATTGTTACCCTTGGGATAACATTCCCAATTTCATTGCATAAATATAACTGCAAATCCATATATCAGAACTGTCAAGGACTCACCATTCATTTGCCCTATCAGAAAAGGCAGAATAAATCTCAAAGGTTGATTGGACTTAGTTTGACACCAAGCCTAGTGTAACCTGGTAAGCTGTGGATTCCCACACCTGCATCCCTGCAGCCATGAAGTCAATGCTTTGGGGCAGGACTCTGTTCGGTGGAAGAAGCTGAAGGGACACACAAGTGGCAATGGGGACATGTGAACAGGAAACAGACAGTGGCAAGCAAATGGCAGGTCCTAAGCAAGGCACACAATTTCCTGTTCTTTACATATAAATTCCATTGAGACAATTAAACTTCAGAAGAATTTGCTGAATAGTATCATTAGAGATTTTGGAATCTACGATTAAAACTTCCATAGGTCTGGAGTTTTGGATGTGGTTTTGCCTAAAACGAAGAGATTGAATGATATTTATGTGGCCTCTGCTCTTTTTTTTTCCTAAAAGGTTCATCTTTCAGGAGGTAAATATTTCCTTTCCATGAGCCCATCTTTGCATCTTTACTTTAATAGTTTTATTTTCAATACTTCATTCTCTCTTTTCTCCTTGCTTCAATTACTCCTGCATCTTGTAGTTAAGCTGAGCTGATAGCATGGATCTTTATCCCCATTGGTGATAACATCAGTTGAGTAGAAATCCGTTTGAAATACCCAGTCATGCAAATGATTAACATAGCAGTAATGGCCATTGCTCATATCCCAGTGATGTCTGGATTCATAAGCAACTCTTAGGTTGCCATTTAGGCAACAGCAGTAACACAGAACTAAGAGTCTCACTCAGACTTGCCTTTGAAGTGCTTGAGATTCTTTTCTTTGTCCTGTGTCTGTTAACACCATGCTGGGTAGAAACATGTTCCTACCTAGCTCCAAACCTGGAGAGTGTCTTAGGGTAGGGAATAACTGAGTCATTGTGTGATTGTTAACATCCAAACACTCCAACTGGCACGTTCCAAGAGTTGCGATATTTTAAGTAGCTCATCTGTGAATAGATCAGTTTCATAAGTATAAGATAAAAAGATAGGTGAGCTAAGATTATTTTAAAATATGAATATTGGGAAACGATATCTGTCTCCAAAAACAGAAATATTTTACATACAGAGTTTATTTTTTTAAGGGAACTATTATGGAAGTATAAGATGAAATGATAGGTTAGCTAAGATTTGTTTTTTTTCTTAAATATGGTTATGGAAAATGATTTCTGTCTCCAAAAAAAAAATAAGAAAATATTTTACATTCAGAGCTCACATTTTAAGGGAACTATTATGGATACATATTGGATAACGATGCCTTTTCACACCTATTTATAACGATCTAAAAACGGACCTGGGAGTACATCAGAAACAATGCGTTTCAGTTTGAAGATGGAGGTTGAAATGGGTGAGATGCTCTGAGTTTATACAGTTGATCTTAGTTTTGGTCCTTCCAAGCCAAATTTCTGGCATGGAGAAAGCTGGAATCACAGAAGACTGAAGGGCTGATAGACTTTCAAAAACAGTCCGAATATAGTAATTCTAGGAATATCACAGGGAACTATTGTGGTCTAGCTATGAAATGTCTACCATGGGCTCATATGCCCCAATCATGGCTGTCTAGCTGATGGTGCTATCTGGGAACGTTGTAGAACCTTAATGAGTAGAGAACAGAAGAAGGTGTTAGGTTGCCAAGGATGGGATTAGAGGCTTTATAGCCTGGTCCCACTTTCTGTTCACTGCCAGATTCCTGAGTGTAGACAGCAGATGAGTGTGACAAGCCAGTCCCCTTTTCCTGTCACTATGCCTACCCTTTCTGCTGCCATGTGGCCTCTTCCAAGTAGGCTGTACCCACTTGAAACTTCTATGAGTCAAAAAAGAGTTTCTCTTATGCTGCTTTTGTTTGCTGTTTTATCGCTGCAATGAGAAAGTAAGACACTCCTTACATCTGAGGAAGCATGTAGAACTCTTGGTTAAGTAACATCTACAACTGGAGTGCTCTGAGGTTTGTTACCGCCAAGAATAGTGATTATTTTGTTGTCTGGAATTTTGGTATTTCAG
Seq C2 exon
GGCACAACTACTGAAACAGAAATAAGGAAGAGGAGGTCCAGTTCTTACCATGTTTCTATGGACTTGTTGGAAGACCCTACATCAAGGCAAAGAGCAATGAGTATGGCCAGCATTTTGACCAACACTATGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000075318:ENSMUST00000028377:12
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.598 A=NA C2=0.449
Domain overlap (PFAM):
C1:
PF119333=DUF3451=FE(51.3=100)
A:
NA
C2:
PF119333=DUF3451=PD(16.5=82.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types