MmuINT0139650 @ mm10
Intron Retention
Gene
ENSMUSG00000075318 | Scn2a
Description
sodium channel, voltage-gated, type II, alpha [Source:MGI Symbol;Acc:MGI:98248]
Coordinates
chr2:65730106-65733351:+
Coord C1 exon
chr2:65730106-65730279
Coord A exon
chr2:65730280-65733228
Coord C2 exon
chr2:65733229-65733351
Length
2949 bp
Sequences
Splice sites
5' ss Seq
GATGTGAGT
5' ss Score
7.77
3' ss Seq
TTTGTGCTCTTTTTGTATAGGTC
3' ss Score
10.12
Exon sequences
Seq C1 exon
GCCTTTGAAGACATTTACATCGAGCAGCGAAAAACCATCAAGACCATGCTGGAGTATGCTGACAAGGTCTTCACTTACATCTTCATCCTGGAGATGTTGCTAAAGTGGGTTGCATATGGTTTCCAAATGTACTTCACCAATGCCTGGTGCTGGCTGGACTTCCTGATCGTTGAT
Seq A exon
GTGAGTACTCTGCAGTTCCCTTCTCTATTTCTTGGCAGGTGATGATTAGAACCTGTCCTGACTGTATCGAGTGGCACAAAGCAGGAACTCAGAGAAACGAAATGCTGTTTCAGAACAAGTACAAATTCGATCTTTTTTTCTTCTCCCGTGGAAATATACCCGAGACTTGCTTTGTCCATTTAAGTGGCAACTGATATTTAGTGACTTCGTTTGAAAATAACATTCAAATCAGTATATGAAATTTTAAGCTCTTCAGGAGAAACAAGATTGTTTTCTTTGTTGCTTAATTCTCAAATTTCATAAAATCAAAGCTGTTACAATTTTTTACAAGCATCTTCACCAATAGTAATTTGTCTGCATGTAAGCATCCTGAGAAATATTTGTCCCATTTGAAGTTAAAAAGAAAGGTATACCATGGGTTTATCTGGTGATTAAAAACAGATTGGCTAAGCAATCTTTTAAGTATTTAACTTGTGTTAATGTTTAAAGATAGTAAAATAGAATATTAGAATGTAGAAGTATCTTAAATAATTGAATATGGTAAATTAACCATAAATGTAACATCTAAAGGTACATTCAAAATTGCATTGAAAATCTTGAAATGCAGAAAGAAAGTTAGCAAAAAAGTAAAGCCATAGATGTTTGTCTGTTTGACCATTACAGATAACAAAATAAGTGTGTCACAAATGCCACCAATTTTATATGATAGGTTGTAAAACACACCGTCCTTTCCACTTTTTGTATGTAACTATGACAGATCAGTAGCTTCATGGTAGCATATCTAATATTTAACATATGAACAAAGGTAAGCCACTATATCCACATTAATTAACTATAAAGAAAGCCAAAAATAATTTTTTGCTCCCTGATAGCTACTATTTTAGGTTTGTGAATACTCTCATAATTGCATGTTAAATTAGTTGATACTTTGTTTTTAATTAAACATGTTCTCTGATCATCTGTTTTTTTATGGTGCTATTAATAGAAATGTCATTTTGCTGGAGCTTAAGGTTGACCAGAAAAGACAAATGTATAGTCGTTGGCTTCCCTTGAGGGAAGGGTGTTTTTTTCATGTATCATGAATCAGGATTTGAGTGGTAAGAATGCCAGTAGGTCTAGAGGAGGGAGGAACATTCAATTGTGCCAACTCTGATGCCTCAAGCCAAGAAGTCTTAGTCCTTGAGGGTGAGAACAGAGTGCAGGGAGTAGGGTGCACTGATTTGTGAACGGAAGGCAAAGTAAGAAAGACAAATTAGACATGTGTTTGTGGGAACCCATTATACCATCAAAGAATTATGAATGTATGGATATAGTGGAGAGGAAGACAATTGGAGAATTGGATTTAGGGACGTTAGGAGATGGGCTTGCTGTGTTATAGAGAGAAGCTGGTGAGGGTGTGAATCCTGAAACAGAAAGGGGATTATTGCAAATACAAGCAAGTGCTCAGAAAATTAAACATTTTCATGGTGTGCTAGGAAGACCCAAATGTATCTCTTTTTCAACTGTAGCTAAACAACTCACCAAAAGTGTCCTGGTTTACCACCTCACTTTTTTAATAGTTAGGCCCCAGTTCAGAACATTTTTCACTTGTCTAACTTGTCTTTCATCCTTTAATATGTGTCTCACCTTTGGATTCTGCCTCCTGAGAACATAAAGGACTGTAGGTCCTCCTGGCTTACATACAGAAAGCCTTCACAGTTCTTGATTATTCAGACTTCCTTCCTCAGTTATCTATGAAGAGAAGACTTACAAAGCTTACAAAATTGGCTTTTGTACCTTGTTTCCCTCTTTAATTCAGATTATACGTAAAAATTAACTTAAATAAGCACAAGTTTTGTAAAAGAAATTCCATTCATTTCTGTTGATTTTTAAGAAAACATTTAAAAATAAAAGTATCAGCATCCTTTTCAACCATATCATGTATTTATTTTGCTTCTCTGATTTTCACATTTTTATGTGCTTTCGCACCAGATATCATTTCAGAGTTCATATGAAATTCATAGTTTGCAAAGGTAATCAGGTACTTTAGTGATGTCTGCAACAGCTTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTCTCTCTCTCTCTCTCTCTCTCCCTCCCTCCCTCCCTCCCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTTTTCCAGTTGAGATTTTAGAATTTTTGCTAATTGCACTGGTGATCTGACTAAAAAAACAAAACAAGGGTTTCTAGAGGGAAAACTGGGAAAGGGGATAACATTTGAAATGTAAATAAAGAAAATATCCAATAAAAACAAAAACCCTTTAGGTATACTAAAATCTCAACTTTTCTTTTCATTCACTGATTTTTATATGCTCTAATTATGACGATTCTCAAAATGTGATTCAGGAATCAATGCTATTGCTTATCCATAAACTTGTTTCAAAATGTAAATCTTCAGGCCTTTTACCGAACTTACTAAACCAAACTGTGCTAGCTCCCGTTTTTTTAATTGAAAATAAAACTTTCCATATATTATATTCTGATCACAGATTCCCCTCCCACAACTCCTCCCATATTCTCTCCACCTGCCCACCTCCCACCTCCCCACCTTCCCACTTCCCACCCATTGAATCCACAGCCTCTCCTCTCTCTTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCCCTCTCTCTCATCTAAAAAGCAAGGGCAGGGGGACAAAACAGAGCATGACATTTCTGCTATAGCTTTTTGCAGTGTTTTGAACAAGTATCTTGGTGACGGGGAAACTCACCCAAGTTTGTGAACTACTTGCTTATTTTTTCCATGTAGGAACGCTGTGGCATGTAGACTCTTATTGATAACTTTTAACCAATTTTGTGCTCTTTTTGTATAG
Seq C2 exon
GTCTCACTGGTTAGCTTAACTGCAAATGCCTTGGGCTATTCAGAACTTGGTGCCATCAAATCCCTCCGAACATTAAGAGCACTGAGGCCTCTACGAGCCTTATCCCGATTTGAAGGAATGAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000075318:ENSMUST00000028377:20
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=PU(17.0=67.2)
A:
NA
C2:
PF0052026=Ion_trans=FE(17.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types