Special

MmuINT0157247 @ mm9

Intron Retention

Gene
ENSMUSG00000048720 | Tbc1d12
Description
TBC1D12: TBC1 domain family, member 12 [Source:MGI Symbol;Acc:MGI:2384803]
Coordinates
chr19:38991102-38994413:+
Coord C1 exon
chr19:38991102-38991360
Coord A exon
chr19:38991361-38992360
Coord C2 exon
chr19:38992361-38994413
Length
1000 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGAG
5' ss Score
7.1
3' ss Seq
TTGTTTCATGCTATTTGCAGGTC
3' ss Score
9.34
Exon sequences
Seq C1 exon
GATCTTCACATTGTACAGCAAATCACTGCCACTTGATCTGGCTTGTCGAGTCTGGGATGTGTTTTGTAGAGATGGGGAGGAATTTTTATTTAGGACTGGATTAGGGATCCTCCGGCTATATGAAGATATACTCCTACAGATGGACTTTATTCATATAGCACAATTTCTTACCAAATTGCCAGAAGATATAACATCAGAAAAGCTTTTCAGCTGCATCGCAGCCATTCAGATGCAGAATAGCACCAAGAAATGGACTCAG
Seq A exon
GTAGAGTGACTTTATTTATTTTTAACTCTTAATTATCTGTGTTAAAATTATCTGTGGACTTTTGTAGAGCAGTTATCTGTATCACAAATGTTAGTAAAACTAAAAATAAATTTGGTTTTGAAATGGGATAATTTAAAATGGATTTCTCTCTTCTATGTACCTAAACTTATATCTTTACTTTACAAAGTTCTGCAGTATTGTAGTGAATTGACACCTACAGTAGTCAGCCTTCACCCGAGCAGACATGGGTGACTTTGAGATTTCAAGCAGGCACATGTTATAGTAAACACCTGCTGTGAGATGTCGAGGTGGGTCAAGGGCAAAGGTGCCTGTTGCCATGGGTGACAACAAGGATGAGATTATTCTCTGGGTGCCACACAACGGAAGGAGAGCACTGACCTCACACATGCACCATGCACAGGCATGCTGACACACACACACAAACCCAGGCAAGCAAGCACACAAACGTTAAAAACAAGAGGCCAACACCAAAAAGCCCTAGCTGCTGTGTACTAAAAACTTACAACGGAAAGAACCTAATGTATGATCCTGGCCTCTTGTTGTTTTGAGTCAGGGTCTCCTTTAACGGAGGCTTGACTTGATCTTATTGTGTAGCTGTAAGGATGACCTTTGTCTTAGTCAGTGCACTGTGCTGTGAGAGACACCGTGGCCACAGCACTTCATTGTGTCCTTGCTTACTTTGGTCCGTGATGTTGACGGTGGGGAGCATGGCAGCATTCAGTCAAAATAAAAAACCAGGTGATCTGGAGTCTGGGATGGGGGCCTGTGCCTGTAATCTCAGCAGTGAGGTGGCAGCAAACTCAGCCGTTCAGTCTCCTCTGCTGAGCAACAAGTTCAGTGCCAGTGTGGGCCATGTAGACCCTGTCCAGAGACCTTTAAAAAAGGTGGTCTGAGGACTTGAGGATGCTGGTATTTCAGAAAAGCTTTCTGTGTTTATGCCTCTGGTTATTTACATCTCTTTGTTTCATGCTATTTGCAG
Seq C2 exon
GTCTTTGCATCTGTAGCAAAGGACATTAAAGAAGGGGACAAGAACACCAGCCCTGCTCTGAAGAGCTAACCTTTGAGTTAGTGACAAACTGAAATGCAAAAGGTAGTTTTCGGGGAAAGTTTTCTCTTTCCTATGTAGATACCGTGAAGAAATGTCGGAGAGAAGAATCGGGACCTGGAAAAACTTCTGGGTTTAAATTCCACGGCTGAAGTAAATGAAACGCGTAATTTATTGACAGTATTAATAAAAAAGTACCTGTGGAGAGCCATTTTTCAGAGGAAAAGGCTTAGTTGGCTATTACATACTCCATAATTTGGAGTGAATACTTTAATGCAATAATTTTTTTTAAAAAAAATAGCTTCACAGAAACTTCAATTTTTATGTCGTTTCTTTTTTAACAATTAACTACAAATGCACTTCTGGAGTCAGAATAGGATTGCTAAATCCTACTTTAGTCTCCAAAAATGATAGAACACATGTATTATCTCCAGTTCTGAGCTTGGGAAGATATTCTAGACCAGTAGTAAGCAACTGAGTCGTAAGTTCCGTCCGCCACTGGAGCTCTTGCCTGCCTTGCTCGCAGGCCAGGGAGGTCCGCATCCTCGAGAACTGGAACACTGGTGGACATGATTGCCTGTTTTGCTTATGGAGTTTCCCACAGTGTTGTGTCCCCTTGGTTTTTGAAGAGAAATCTTTCTCTAAGTAATTTCTATCACAAAAGAATTTTCGCCTTATTGTTTCTTGTCTGCAAATTGTTATGTAGTAACTTAACATTAAAAAAACTAGGTAACTGGTAGAAAGGAAGATCTTTTTGCACTTTAGAGGACTGAAGACTTGACTTTGAGAATAAGAATAAGAAAGCAATGAATTCTAAGAGTTCGAGATAACACACTACTTACAAGACTTGAATTTTTTAGTTAAAATCCATGTTCTATCTATAGAAACAAATTTTATTAATTTCAGTTTGAAATTTAAAACTTTATATAGCTAAGTCTAAGACTTGTGAAACTCTATGCATATTTTTTTCTAATTGATGGGAATAATAGTAAAAGTAATTTTACCTTTTTTCTTAGTCTAATGGCATCTCAGATAAACTATTAATCATTGGTAAATTGACATTAAATTTATTACTCTTAATTTCTTAACCTAACCTAAATCATTTGAGTATTATGGTTAATATCAGTATAAAATACTATTTGGTTATTGATTAGATTTATACTGTTCTGATGTTGCAATTTGGTTTGAAACAACATAGAAGCACACATTTCTGTTAGTAGTGGACATACATATATATAGTCTTTAGACTAACAAGCCAGAGATTCTTCCTTATTGGATAATAAACTGCCTTAGGAGTATGGGACCAGAGGAAGTGCATATATTTTTACCCTATGGGTTGATCATTCTAGCCTCAGGAACCCTGTAGAATTAACTCCTGTCATAGGGGCTAGCTCAGTGAAACTGGTAGTATAATAAAACAGTGAGGGAGTTTCTAGAGTCTTAATAGGTTCTAGCATGAGGACTATCCCTTAATATTGGTGTCTCTCATAAAAGGCACATAACCTCCGGGAGTAATCTCATTGAATTTATATTACTTGGCCTAGATTTAATCTTATTTTCATGTATTAGTTTGCTAAGGTGGTCCTACACTCTGCATTTCTTTCCCTTATTTTTTTTATTGTACAGTTTCTTTACCTACCAAGTATAAATGTGTATATAAAATGTAAATACAAGAAATTCACTAAAATCCACTAGTAACAATTACTATGAAAAATAAAACTTGTACACAGAATTATGAGAAAATGAGTCTTCATTACTTTGGTGCCTTCAGGTTTAGTCAACATCTAGAAAAAAAGGAATAACTTTTTTTGTGGGGGTGCTCAGATTTCTCCTCTAAGGAATCTATGAGATAGTCAGTGCTTTGAGCCTTTCAGAGCAGCTGACATACTATACTGTTGTATGTTCATTCCCTTTGGGTCACGTAAATAGGCAATAATGTGATTAGTCATGTGACCCCACACAGCATCCATCCATCCATCCATCCATCCATCCATCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000048720-Tbc1d12:NM_145952:12
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
Alternative protein isoforms





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.136
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0056613=RabGAP-TBC=PD(19.9=51.7)

							
A:
NA

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000037884





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000087470
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr10:94531461-94533027 
LOW PSI
HsaINT0163977
(TBC1D12)
Human
(hg19)
chr10:96291218-96292784 
HsaINT0163977
(TBC1D12)
Rat
(rn6)
chr1:257596071-257597875 
Cow
(bosTau6)
chr26:15849038-15849913 
LOW PSI
BtaINT0145399
(TBC1D12)
Chicken
(galGal4)
chr6:19642675-19643577 
LOW PSI
GgaINT0040083
(TBC1D12)
Chicken
(galGal3)
chr6:21166931-21167835 
LOW PSI
GgaINT0040083
(TBC1D12)
Zebrafish
(danRer10)
chr12:5389852-5392366 
LOW PSI
DreINT0160550
(tbc1d12b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CCACTTGATCTGGCTTGTCGA

				
R: 
TCCCCGAAAACTACCTTTTGCA

				
Band lengths: 
347-1347

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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