MmuINT0162646 @ mm9
Intron Retention
Gene
ENSMUSG00000054537 | Tmprss11e
Description
transmembrane protease, serine 11e [Source:MGI Symbol;Acc:MGI:3513175]
Coordinates
chr5:87142744-87144703:-
Coord C1 exon
chr5:87144523-87144703
Coord A exon
chr5:87143004-87144522
Coord C2 exon
chr5:87142744-87143003
Length
1519 bp
Sequences
Splice sites
5' ss Seq
AACGTAAGT
5' ss Score
10.74
3' ss Seq
TATTTATTTGTTTTTGGTAGACA
3' ss Score
5.52
Exon sequences
Seq C1 exon
GTTGTGGGACACGACGGAACAAATCTACAGTACAGACTAGTGTGAGGATTGTTGGAGGGACACCAGTAGAAGAGGAAGAGTGGCCATGGCAAAGCAGCCTGCGGTGGGATGGGTCCCACCGCTGTGGAGCAACTTTGATCAACAACACATGGCTTGTGACTGCTGCTCACTGCTTTCGAAC
Seq A exon
GTAAGTCCTGACCTTTGAGGATGGGGCCGAGGGAAAGTGAGTGTGATTTTACATTATATATTCATGAAATAGTTGACGAGTTTTGAGAAAGGGTGTCACAAATAGAAAATAACATGTTTACCATAAAATATACTGGGGATCTCAAAAAAAAAGGTTTTATGGTCTCTGAAATGTTGTCAGAGTACACTGCTGTGGTGTAATTACTCATTGATAAATTTATGATACCTCGCTAAAGAATATGGGAACATTAAGTCCTGTTTGAATTTTGAGCTTGTTTTCAAAAGGAGGAACTGATAGTCACTGAGTATCCTTATCAGAACCCAAGGTTCTGCAGATGGTAGGTTTGATCCCTGAGAGGATATTACAAGAAGAAAGATAAGGAAGTGTGAAACAAGTTCAAAGTAGCAAATTTTACAACTGAATAGTTGATGTATTTTAGAATGAAATGTTGAGTTTCTAACCTGGCACCAAAATATTTATCATATACACAGTGGCAAATCTTTTTAAAGTTATCTTTGACCTTCGTAGACTTCTGAAAAATACACATCCTTGTAGGAAGAGGATGTGGGCACGTAGGATGTATTCAATGTCATTCACTGTAGGATTTTCTTTTTTCTTTTTTAAAGCATTAAAATGGACTATTACATTTTTTATTAGATTTTTTTTAATCTACATTTCAAATGTTATCTCCTTTCCTGGTTTCCCCTCCAAAACCCCTCTATCCCCTCCCCCTCCTCCTTCTCAACCACCCACCCACTCCTGCTTCCTGGCCCTGGCATTCCCAGCACTGGAGCATTGAACCTTCACAGGACCAAGGCCTCTTCTCCCATTAATGGAGCAGAGACTAAAGGAATGACCATCCAGAGACTTCCCCACCTGGGGATCCATCCCATATACAACCACCAAACCCAGACACAATTGTGGAAGCCAACAAGAGCTTGCTGACAGGAGCCTGATATAGCTGTCTCCTGAGAGGCTCTGCCAGTGCCCGACAAATATAGAAGTGGATGTTCTCAGCTATCCATTGGACAGAGCACAGGGTCCCCAATGAAGGACCTAGAGAAAGTACCCAAGGAGCTGAAGGGGTTTGCAGCCCTATAGGAGGAACAACAATATGAACCAACCAGTGCCCTGAGAGCTCCCTGGGACTTAACCACCAACCAAAGAAAACCTATGGTGGGACCCATGGCTCCAGCTGTATCACTGTAGGATTTTTCTTTGCACATGTTGCTTGTAGCCACTGATGGTAAAGGCCTCTGTATCTGCAGTGGACATCATGATGCATGGTTTTACATTTGATCTAGGAAGAACACCCTGTGGTTTTTCTGTCTGGCTTGAACCCAGAGCCCAGATCTTAGACTGGAAAGAGTTTACTTTCTGTTGCTATGAACTATAACATAAAATTTCTTATACGGCTACCTGCAGATAAAAATCATTCCTTATAAAGTATTACATTGATGTCAAAGTAAGCTATACTTTATTATTACTGGTATTTTACTTATTTATTTGTTTTTGGTAG
Seq C2 exon
ACACAAGGACCCATCCAGATGGAGTGCTACCTTTGGGGCAACATTACAACCTCGAAAACTGACGACAGGCATCCGGAGGATAATTGTTCATGAAAAATACAAATACCCGTCCCATGACTATGACATTGCACTGGCAGAACTGTCTAAGCCGGTCCCCTGCACAAATGCAGTGCATAAGGTTTGTCTCCCAGATGCAAACCATGAGTTTCAGCCGGGGCAGAGGATGTTTGTGACAGGATTTGGAGCATTGAAAAATGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000054537-Tmprss11e:NM_172880:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.098 A=NA C2=0.011
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(19.5=72.1)
A:
NA
C2:
PF0008921=Trypsin=FE(38.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGAGGAAGAGTGGCCATGG
R:
GTCACAAACATCCTCTGCCCC
Band lengths:
347-1866
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: