Special

MmuINT0162660 @ mm9

Intron Retention

Gene
ENSMUSG00000045631 | Tmprss12
Description
transmembrane (C-terminal) protease, serine 12 [Source:MGI Symbol;Acc:MGI:1922252]
Coordinates
chr15:100112663-100115825:+
Coord C1 exon
chr15:100112663-100112858
Coord A exon
chr15:100112859-100115556
Coord C2 exon
chr15:100115557-100115825
Length
2698 bp
Sequences
Splice sites
5' ss Seq
TAGGTAGGT
5' ss Score
7.92
3' ss Seq
GAATATTTGCTTTCTTTCAGAGA
3' ss Score
8.7
Exon sequences
Seq C1 exon
ATTGTGGAATAGCACCACTTAGAGGTGCAGTGGAAGGGTCTCGGATTATAGGAGGTTCGCAAGCTGACACTGGTGCGTGGCCATGGCAGGTTAGCCTGCAGGTTCAAGATGGCGATATTCTTATGCATGTATGTGGTGGCGCCCTAGTGAGAGACAGGTGGGTCCTCACAGCTGCTCACTGCACAAAAGAGGCTAG
Seq A exon
GTAGGTATTCATAATACAATTCTCATTTTCTTCTCTCAAGAATAGTTTGAAATGGTCCTGACTTTAGTTAAGCATTGTGTCTATGGGATGTCTACATATATATGCATATATATTCATATTCTATTTGTGTATGTAAAGACATACGTTGTTCATGGGTACAAGGCACTTCCGGGGTTAATCTTTACTATTTGAGGTCTGACAGAGACTCTTTGGCTTCATTTGCTTAGAGTCATACAACCCACTTTCTTTTTTTTTTTTAATTTTTAAAAAAGATTTATTTATTCTATGTAAGTACACTGTAGCTGTCTTCAGACATACCAGAAGAGGGAGTCAGATCTCATTACGGGTGGTTGTGAGCCACCATGTGGTTGCTGGAATTTGAACTCAGGACCTCTGGAAGAGCAGTGAGGTGCTCTTACTCGCTGAGCCATCTCTCCAGCCCACAATCCCACTTTCATGTGATTTCTGTGACCAAAACATCATTTCCAAAGCTGCCTCCGTGGCACATGGATGGAGAATTCTCAGTTTCCATCCTAGTGGTTATACGGTATAGGGCAATTATGACAGACTTTCCTAAAGTGTCTCTTTGCTTTTTCTAAAACAGTTTCTTTTTTATGCATGTGAGTGGTATGTGTGTATGTATGTATGTCCACTGTGTGCATCCCTGGTGCCCAGGGAAGCCAGAGAGGGCATCTGGAATTATAGATGGCTTTGAGTATCAGAAGGATGCTGAAGGAGAGCCCGAGTCCTCTGCAAGAGCAGTAATGCTTTTGACACCAGCCAGCTCTCCAGCTCAGAAGCATCTCTTCTAAGATGCTGGTGAGCTGTGGGTGTGTGTGTATGTGTGTGTGGGGGGGGGGATGGCAGAATGGCACTTTACTCTATATATGACTCTTTGCTAACTAACTTTCTCATCAACTTTTATGATGGATTATCTGATCGGCTCAGCCTTGCTTTTCACTTTATTTGAAAGCAACATTGTGCAGTTTGTTAATGAACCATCCTTTGGTCAAGGATCCATCCCTGTCCCACAGAACTCCAAAGGGTTTGGATCATGTATATTAATTAAATCAGGGCACCTTGATGACAAAGTGGGTAGATCTTGTACAAGCACATAGGTATTTGCCGCTAAGCACCAATGTACACTTCTAGCAAAAGGCAGCGGATTTTTGCTATTCTGTGGTCCTGGGGGCTGAACCTAAGGCTTCACCCATGCCAGGTAAGTATGGAGCTCCTATTTCCAGCCATGCATATAACACTGAAAAGAGTGTGTGTGGAGGGATAGAGTTGACGCCCATTATCATTTCTCATTTATCTGTTTATTTTCTTTTATAACTGTGGTATAATTTCATGCCTCTGTGGGATTATCTAGGTTAGTTGAAGCGGGATCCACCCTGAGGGAGGTGACTTTTCTTTCTTAGCCTGAGTGAAAAGGAGAATGGAGCTAAGCACTGGCTGGCCATCTGCCTCCCTCTGCTCCCTTCCTGACAAACGAGTCTAGCCTCCTGAAGCTCCTGCCTCCTTGCTTTCTCTGCTGTGATGGACTACGACTGGGAACCAGAATAAAGCCTTCTCCCTTCCATTGGTTTTATTGGGGTAGTTTATCCCAGCAGTGAGACAACTAGTAAAACTTTGTCTCAAAAACCAAACCAAACTGATACAAAAAATACCAAACCCAAAAACCAAACAACAACAACAACAACAACAACAACAACAACAAAACCCAAATAAATCCTGTCTCATGTTAGAGTCCTATATTCACCTGTCTTCTTTTTAGTTTAATTTTTAAAAATTCTAGTGCTAAGATCCATATGTTTTATTCTAGTGTATTTCCAAAAATGAGGGGCCTGAGAGATGGCTCTGTGGTTAAAAGCGCTGGCTACTCTAACCGAGGACCAGCTTTGAATCGGCAGCTTACAATTCCCCGAGACGCCAGCTTCAGGGCATCTCATGCCCTCTTCTGGCATTCTTGGGCATCAGGCACACACATGGTACACAGATATAGATGCAGACAGAAAACAGACAGTTGATTTTTAAATCTTAAGTTAAAAAAGGAGAGGACATATTTTCTCACATGCTTATCACATAGCTTCAAGTTTTAAACTTACATCTTTTAACAATCTTTATCAGTGTGTATTAATTAAGCATGCCATGACATTTTTATACATGTATGTAATGCATTCACTCGTGCACCCCTCTGGCTCTCTCCCATCCATGCCTCATGGGTGCTGAGCCTGCACTGTGCAGGGTTAATCTTCTCCTCCCACTATTTCAAAGCAGATTCCAGATCTATCATGTTGCCTGTCATAAAGACAGCACCTCTTATTGAAAAGAACTTGAAGTTTTTAATCCATTTGGGGTTTACTTTGGTGGTTTGTGTTATTTCAGGGATTTAACCTTTTCTTTCCAAATAGGTAGTTGTCTCAAAACCACGAACGGAGTGACTTAGCCCTCCATTCACTAGTAGTTCATGCTATCCTAGTCAGCCATGAAGTTCTCATGTGCTGGAGTCTGGTCTGAGTATCCTGCCCCATTCAATTCTCTCCACTGCTGTGTCATGAGGTTTGGTCTTTTATTTTATACTCTATGTCACATGGAAATACGCTTACAACTTTGTTGTCAGGCTGATATCTAGGGGAAATGAAGGAAAATTATTTAAGTGGACCTCTGGGTAATAAGAATATTTGCTTTCTTTCAG
Seq C2 exon
AGATCCTCTGAAGTGGAGAGCAGTGATGGGGACCAATGACCTCACCCGGAGCCCCTACCACAGCAGGAATATACGAATCACAGACATCATCATACCACCAGATTTCATTATGGAAACTTTCGTAAATGATATCGCACTGTTCCGTTTAAAGAGAGCTGTGAGGTATAATGACTATATTCAGCCCATTTGTCTACCTTTTGGTGTTTTCCAAAAACTGGACCAAAACACAGCGTGTTTTATAAGCGGCTGGGGAAGAACCAGAGAAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000045631-Tmprss12:NM_183109:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.027 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0008921=Trypsin=PU(21.2=75.8)

							
A:
NA

							
C2:
PF0008921=Trypsin=PD(84.7=84.0)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000093914





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000063018
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr12:50844038-50858784 
ALTERNATIVE
HsaINT0169660
(TMPRSS12)
Human
(hg19)
chr12:51237821-51252567 
ALTERNATIVE
HsaINT0169660
(TMPRSS12)
Rat
(rn6)
chr7:141955102-141958133 
LOW PSI
RnoINT0153333
(Tmprss12)
Cow
(bosTau6)
chr5:29230284-29248304 
Chicken
(galGal4)
chr15:341581-348997 
Chicken
(galGal3)
chrE22C19W28_E50C23:107998-108623 
GgaINT0000800
(TMPRSS12)
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"