MmuINT0166414 @ mm10
Intron Retention
Gene
ENSMUSG00000026812 | Tsc1
Description
tuberous sclerosis 1 [Source:MGI Symbol;Acc:MGI:1929183]
Coordinates
chr2:28672393-28672903:+
Coord C1 exon
chr2:28672393-28672504
Coord A exon
chr2:28672505-28672781
Coord C2 exon
chr2:28672782-28672903
Length
277 bp
Sequences
Splice sites
5' ss Seq
CTGGTATGT
5' ss Score
8.14
3' ss Seq
GTCTTGTCCTTGTCTCTGAGCAG
3' ss Score
-1.16
Exon sequences
Seq C1 exon
GCTAGTCTCTGGAGCCCATCTGCGGTCTGTGGTATGACCACTCCTCCTACGTCTCCTGGAAATGTCCCAGCTGATTTGTCACATCCGTATAGTAAAGCCTTTGGTACCACTG
Seq A exon
GTATGTGGATCTTAGGTGGACTTGATTGCTTGGTTTGGGCCTGTGTTTTGTGACTCTGGGGGCTATGTGGCAGTAATAAACTTGTTTTTGAAATTTAGTATTAGTTTCTGGGCTTCTTAGAATGAGTAAAGAAACAGACACTGAGGCTGATCTGGATTCTGAGAAGTTAACTGGATCACCATATTTGTAGTAGCAGCAGTGTTAAGGAAACAACAGTCTTTTGTTTTGTTTTGTGTCGTGTGGCTCAGCCTTTCTATGTCTTGTCCTTGTCTCTGAG
Seq C2 exon
CAGGTGGAAAAGGAACTCCTTCAGGAACCCCAGCGACCTCTCCTCCTCCAGCCCCACCTTGTCCCCAAGATGACTGTGTGCATGGTTCAGCAGCCCAGGCCTCAGCCACAGCCCCCAGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026812:ENSMUST00000113869:11
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.892 A=NA C2=1.000
Domain overlap (PFAM):
C1:
PF043887=Hamartin=FE(5.2=100)
A:
NA
C2:
PF043887=Hamartin=FE(5.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAGTCTCTGGAGCCCATCTGC
R:
CTGGGGGCTGTGGCTGAG
Band lengths:
228-505
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types