MmuINT1008691 @ mm10
Intron Retention
Gene
ENSMUSG00000030409 | Dmpk
Description
dystrophia myotonica-protein kinase [Source:MGI Symbol;Acc:MGI:94906]
Coordinates
chr7:19088001-19088996:+
Coord C1 exon
chr7:19088001-19088264
Coord A exon
chr7:19088265-19088910
Coord C2 exon
chr7:19088911-19088996
Length
646 bp
Sequences
Splice sites
5' ss Seq
GGGGTACGT
5' ss Score
7.73
3' ss Seq
AGCCCTGTCTGTCTTCCTAGGAG
3' ss Score
9.35
Exon sequences
Seq C1 exon
GAACACTTGTCGCTGCCGCTGGCAGACACAGTTGTCCCCGAGGAAGCTCAGGACCTCATTCGTGGGCTGCTGTGTCCTGCTGAGATAAGGCTAGGTCGAGGTGGGGCAGGTGATTTCCAGAAACATCCTTTCTTCTTTGGCCTTGATTGGGAGGGTCTCCGAGACAGTGTACCCCCCTTTACACCAGACTTCGAGGGTGCCACGGACACATGCAATTTCGATGTGGTGGAGGACCGGCTCACTGCCATGGTGAGCGGGGGCGGG
Seq A exon
GTACGTACCTGCAGTTCCTGATCCGTTGAGGGGACTTCCCTAGCCTCTTCCATAAAATTGGGGTGATTGGCCAGGTGTGGTGGTGCATACCTTTAATCGTAGAACTTCATAGGCAGAGGCAGGTGGCTCTCTGGTAAATCAAGGCCATCTTGGTCTACATAGTGACTTCTAGGCCAGTCAGGAGTGAGATCCTCCCTTGAAAAATAAAAAAGGGGGTGTTGACCTTCCTGGGTCCCAAATTATTATCCTAGAGCACTGCTATGTATCCACTCAGGTATGAGGACACACAGGTGACCAGTCCCAAAGACAGTGAGTGAGGCCTCACTCTTGGCAGTACTAAAATTGATTGTAGGGGGCTGGGCTCTTGACCCAGCCTGGAAAGTGCTGGAGGGCTTCCTGGAGGAGGAGACTAGCTGAGCCCAGAAGGATGCAGGAGATCCTTTCTCGGGTGAGTGCTCTCAGCATTTTAACAAGCTCTAGGCCCTGCAGAGAGAAGTCTGGTGTGGGCAGAGCCCCAATAGAAAGCAACAAGATAGAAGAGAAAATGGTGGAGTTTGTTAGTGGGGGCAGTTATGCCGTGAACATAGAGGGGCGAAGGGCCATCTCGGATAACTGCTAGCCACAAGAGCCCTGTCTGTCTTCCTAG
Seq C2 exon
GAGACGCTGTCAGACATGCAGGAAGACATGCCCCTTGGGGTGCGCCTGCCCTTCGTGGGCTACTCCTACTGCTGCATGGCCTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030409:ENSMUST00000032568:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.071 A=NA C2=0.233
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=PD(16.4=50.0)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAACACTTGTCGCTGCCGC
R:
CTGAAGGCCATGCAGCAGTAG
Band lengths:
350-996
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types