Special

RnoEX0021196 @ rn6

Exon Skipping

Gene
Description
cholinergic receptor nicotinic alpha 2 subunit [Source:RGD Symbol;Acc:621533]
Coordinates
chr15:42817273-42820440:+
Coord C1 exon
chr15:42817273-42817424
Coord A exon
chr15:42817821-42817865
Coord C2 exon
chr15:42820331-42820440
Length
45 bp
Sequences
Splice sites
3' ss Seq
TACTTTCTCTGCTACAACAGGAT
3' ss Score
5.47
5' ss Seq
CAGGTAAAC
5' ss Score
7.82
Exon sequences
Seq C1 exon
TGTTGACCCAGCAAGGCTCACACACCCATGCTGAGGACCGCCTGTTCAAACACCTGTTTGGAGGCTACAATCGCTGGGCACGGCCAGTGCCCAACACTTCTGATGTGGTCATCGTGCGCTTTGGATTATCCATTGCTCAGCTCATAGATGTG
Seq A exon
GATGAGAAGAATCAAATGATGACCACCAATGTCTGGCTAAAGCAG
Seq C2 exon
GAATGGAATGACTACAAGCTGCGCTGGGACCCGGCTGAGTTTGGCAATGTCACCTCCCTGCGCGTCCCTTCAGAGATGATCTGGATCCCAGACATTGTCCTCTACAACAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000017424-'3-3,'3-2,4-3
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (Ref)

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
PF0293118=Neur_chan_LBD=PU(18.8=76.5)
A:
PF0293118=Neur_chan_LBD=FE(6.8=100)
C2:
PF0293118=Neur_chan_LBD=FE(17.4=100)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Mouse
(mm10)
No conservation detected
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCCAACACTTCTGATGTGGT
R:
GATCATCTCTGAAGGGACGCG
Band lengths:
145-190
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]