RnoEX0053025 @ rn6
Exon Skipping
Gene
ENSRNOG00000002487 | Mbnl3
Description
muscleblind-like splicing regulator 3 [Source:RGD Symbol;Acc:1565834]
Coordinates
chrX:138388573-138392946:-
Coord C1 exon
chrX:138392760-138392946
Coord A exon
chrX:138390860-138390895
Coord C2 exon
chrX:138388573-138388667
Length
36 bp
Sequences
Splice sites
3' ss Seq
CTTATCTGCATGGTGTACAGGGC
3' ss Score
4.85
5' ss Seq
TTGGTAGGT
5' ss Score
7.03
Exon sequences
Seq C1 exon
GCCCTGCCGCCTGGTGCACTTCAGCTGATACCAAAGAGGTCAGCCCTTGACAAGGTCAATGGTGCCACTCCAGTCTTTAACCCCAGTGTTTTCCACTGCCAACAGGCTCTGGCTAACATGCAGATTCCGCAGCCGGCTTTCATCCCGACAGGTGAGGGCACAGCTCTGGGAATATTGGGTTTAACAG
Seq A exon
GGCCAATACTGTGCATGACTCCTGCTTCAACTTTTG
Seq C2 exon
TGCCCATGATGCACGGTGCTACACCTTCCACCATGTCTGCAGCAACACCACCTGCCGGCAACGTTCCCTACGTTCCAACAACTACAGGCAATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000002487-'10-9,'10-8,11-9
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (disopred):
C1=NA A=NA C2=NA
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
ENSRNOT00000043258fB8467
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAACATGCAGATTCCGCAGCC
R:
TTGCTGCAGACATGGTGGAAG
Band lengths:
119-155
Functional annotations
There are 2 annotated functions for this event
PMID: 21454535
Inferred from MBNL1 ortholog: The exon 7 region enhances MBNL1-MBNL1 dimerization properties
PMID: 27733504
The presence of alternative ex.54nt always significantly elevated MBNL1 and MBNL2 protein levels (_2... [Show more]
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]