RnoEX6011169 @ rn6
Exon Skipping
Gene
ENSRNOG00000020485 | Vav3
Description
vav guanine nucleotide exchange factor 3 [Source:RGD Symbol;Acc:1565941]
Coordinates
chr2:212422692-212428715:+
Coord C1 exon
chr2:212422692-212422778
Coord A exon
chr2:212427056-212427141
Coord C2 exon
chr2:212428583-212428715
Length
86 bp
Sequences
Splice sites
3' ss Seq
AATATGTATCTGTGTTTTAGAAC
3' ss Score
8.8
5' ss Seq
AAGGTGCGT
5' ss Score
9.49
Exon sequences
Seq C1 exon
GACTTGGCACAATATGTGAATGAAGTAAAAAGAGATAATGAGACCCTTCGTGAAATTAAGCAGTTTCAGCTATCTATAGAAAATTTG
Seq A exon
AACCAGCCCGTTTTGCTCTTTGGGCGACCGCAGGGAGACGGTGAAATCCGAATAACCACACTGGACAAGCATACGAAACAAGAAAG
Seq C2 exon
GCATATCTTCTTATTCGATCTGGCAGTGATTGTCTGTAAAAGGAAAGGGGATAACTACGAGATGAAGGAAATAATAGATCTCCAGCAGTACAAGATCGCCAACAACCCTACCACGGATAAAGAGAATAAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000020485-'17-16,'17-15,18-16=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.103 C2=0.000
Domain overlap (PFAM):
C1:
PF0062115=RhoGEF=PD(4.0=24.1)
A:
PF0063014=Filamin=PU(5.9=65.5),PF0016924=PH=PU(17.8=62.1)
C2:
PF0063014=Filamin=FE(13.7=100),PF0016924=PH=FE(43.6=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAGATAATGAGACCCTTCGTGA
R:
GTGGTAGGGTTGTTGGCGATC
Band lengths:
171-257
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]