RnoINT0059654 @ rn6
Intron Retention
Gene
ENSRNOG00000043219 | Fbn2
Description
fibrillin 2 [Source:RGD Symbol;Acc:620910]
Coordinates
chr18:53070412-53072185:-
Coord C1 exon
chr18:53071954-53072185
Coord A exon
chr18:53070590-53071953
Coord C2 exon
chr18:53070412-53070589
Length
1364 bp
Sequences
Splice sites
5' ss Seq
GGGGTAAGA
5' ss Score
7.83
3' ss Seq
GTTTTGCTTTTTGTAAACAGCCA
3' ss Score
6.51
Exon sequences
Seq C1 exon
ATGAGAATGAATGTTCCAACCCCGGTGCCTGTGGCTCGGCCTCTTGCTATAACACCCTGGGGAGTTACAAGTGCGCCTGCCCCTCGGGCTTCTCCTTCGACCAGTTCTCCAGTGCCTGTCACGACGTGAACGAGTGCTCCTCCTCCAAGAACCCGTGCAGCTATGGCTGCTCCAACACGGAAGGAGGCTACCTCTGTGGCTGCCCACCAGGCTACTTCAGAGTGGGACAGGG
Seq A exon
GTAAGACGGCCCAGTGTCCCCACAGCAACAAAGGGTGACTCTTCCTCTCTCCAGAGTGTTCAGGCAGCCTTGCTCACCACCCCTGCGGGCGAATCCCAAGAGGTGAAAGCCTTGGAACTAGGCACCATGCAGTGTAGGATCAAGTCCTTTGTGGAGAGCCTGAGACATGTGTTTCCACAGAAACCTCAGTCATTGGTCCTCATAATGGCTGAAGTTGATTAATCCGGACTCAAGGCCAGATTCAAAGCTTAGTCAGCTCATCTGTACAGTGAAAGACAGATGTGTAAATGACTTCCTCCCCTGTGTTGCTCTGCTGATTTCCACAGATGCTGATCCAGCTACCCCTGAGGAAGGACTTTGTCTCTTTCTCTGTTCATCTGGTTTTATGTTGCCCGAAAAGGGAACAGCCCTTCCTCCCACAGGCTGGTTACCCCTTGGGTCACTGAACCTTCTCAGATCTTACCACTTGTGTGTGGCAGGGTAGTACCACCACACCCAGAGACTGTTCTCTTCAGGGACACAGAAGATGGTAGTCTATAAGTAAATAGGGGTGACCTTCTTTGAAAGAATTAGTAAGTCTAGCAGGCACTAAGTAAGGGGCATGAGCCAATCTGACCAGCACTGATGTTCAGTCACACACAACAGAAATGATTGAGCCAATGAGAGCCAATGCCTTGCCTCCTTCCACTCACTAAAATAGGGATGCAGAAATACCGATTCTTAGAGCAGGGATCTTTGCCTGAGCATTAAGAGCTGGCTTCAGTTTCCCTCACCTTGTCTTGGGGCTTGCACAGCTGCATTTACCTCCTTAAGTGGATTATGTTCAAGTGCTTCGATTTGTATAGGATTGAGAACTAGAGAAGCCCAGGACTCATCCTCGGAAGAATTTTGCTGTTTCAAAACAAGAGGAAATCTTTCCCTCTGTGTGGCAAAGAACAGACCCACAAAGATCAGGTTTTGTGATTACTACAGTTCCTCCTGTTGTGCGGACCCCAACCACAAAATCATTTCCATTGCTACCTCATGGCTGTAACGGTGCTACTGTAAGGAATCATCACATAAACATCTGTATTGTCGGGGTTGGGGATTTAGCTCAGTGGTAGAGCGCTTACCTAGGAAGCGCAAGGCCCTGGGTTTGGTCCCCAGCTCCGAAAAAAAAAAAGAACCAAAAAAAAAAAAAAAAAAGACTTAAAAAAAAAAAACAAAAAAAAAACATCTGTATTGTCCCATGGTCTTAGGCAGACCCGAGGGTTGCGACCTACAGGATGAGAGCGGCTGGCTTACAGCTCGTTCTGCTCCTTGTTTCTGTTTAGACCGCCCAGGCTGATGATAATGTCTAAGGGTGTTTTGCTTTTTGTAAACAG
Seq C2 exon
CCACTGTGTCTCGGGAATGGGCTTCAACAAAGGACAGTACCTGTCAGTGGATTCGGAGGCAGAGGACGACGAAAACGCTCTGTCCCCAGAAGCATGCTACGAGTGCAAAATCAACGGCTACGCCAAGAAAGATGGCCGGCGGAAGAGGAGCGCGCCAGAGCCTGAGCCCGCCTCAGCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000043219:ENSRNOT00000066548:56
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.300
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=51.3),PF0764510=EGF_CA=PU(92.3=46.2)
A:
NA
C2:
PF0764510=EGF_CA=PD(5.1=3.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGAATGTTCCAACCCCGGTG
R:
AGCCGTTGATTTTGCACTCGT
Band lengths:
345-1709
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]