Special

FBgn0005558 @ dm6

Biotype
protein_coding
Gene Symbol
ey
Description
The gene eyeless is referred to in FlyBase by the symbol Dmeley (CG1464, FBgn0005558). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 4:697689..721173. Its molecular function is described by: RNA polymerase II cis-regulatory region sequence-specific DNA binding; RNA polymerase II regulatory region sequence-specific DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding. It is involved in the biological process described with 19 unique terms, many of which group under: growth; sensory system development; post-embryonic development; sensory organ morphogenesis; cellular response to stimulus. 86 alleles are reported. The phenotypes of these alleles manifest in: medulla; cellular anatomical entity; eye disc; hemolymph; visual system. The phenotypic classes of alleles include: increased mortality during development; increased cell death; phenotype; visible. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 06-12 hour embryonic stages.
Coordinates
chr4:697689-721173:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Exon Skipping
174
chr4:717127-717300
+
93.12
53.6
0
Exon Skipping
180
chr4:707492-707671
+
80.24
43.82
0
Intron Retention
5643
chr4:705274-710916
+
33.67
80.8
0
Intron Retention
1410
chr4:711083-712492
+
8.65
65.48
0
Intron Retention
1184
chr4:712674-713857
+
11
51.58
0
Intron Retention
2614
chr4:714513-717126
+
18.85
70.65
0
Intron Retention
353
chr4:717301-717653
+
12.44
69.79
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000007372 PAX6 2-to-1
Human hg19 ENSG00000007372 PAX6 2-to-1
Mouse mm10 ENSMUSG00000027168 Pax6 2-to-1
Mouse mm9 ENSMUSG00000027168 Pax6 2-to-1
Rat rn6 ENSRNOG00000004410 Pax6 2-to-1
Cow bosTau6 ENSBTAG00000004561 PAX6 2-to-1
Chicken galGal4 ENSGALG00000012123 Pax-6 2-to-1
Chicken galGal3 ENSGALG00000012123 PAX6_CHICK 2-to-1
Zebrafish danRer10 ENSDARG00000045936 pax6b 2-to-2
Zebrafish danRer10 ENSDARG00000103379 pax6a 2-to-2