FBgn0010905 @ dm6
Biotype
protein_coding
Gene Symbol
Spn
Description
The gene Spinophilin is referred to in FlyBase by the symbol DmelSpn (CG16757, FBgn0010905). It is a protein_coding_gene from Dmel. It has 12 annotated transcripts and 12 polypeptides (9 unique). Gene sequence location is 3L:2505245..2554292. Its molecular function is described by: neurexin family protein binding; actin filament binding. It is involved in the biological process described with: neuron projection development; negative regulation of presynaptic active zone assembly; calcium-mediated signaling; actin filament organization. 29 alleles are reported. The phenotypes of these alleles manifest in: presynaptic active zone; embryonic/larval neuromuscular junction. The phenotypic classes of alleles include: smell perception defective; behavior defective; viable; flightless; neuroanatomy defective; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chr3L:2505245-2554292:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000108819 | PPP1R9B | 1-to-2 |
| Human | hg38 | ENSG00000158528 | PPP1R9A | 1-to-2 |
| Human | hg19 | ENSG00000108819 | PPP1R9B | 1-to-2 |
| Human | hg19 | ENSG00000158528 | PPP1R9A | 1-to-2 |
| Mouse | mm10 | ENSMUSG00000032827 | Ppp1r9a | 1-to-2 |
| Mouse | mm10 | ENSMUSG00000038976 | Ppp1r9b | 1-to-2 |
| Mouse | mm9 | ENSMUSG00000032827 | Ppp1r9a | 1-to-2 |
| Mouse | mm9 | ENSMUSG00000038976 | Ppp1r9b | 1-to-2 |
| Rat | rn6 | ENSRNOG00000008869 | Ppp1r9a | 1-to-2 |
| Rat | rn6 | ENSRNOG00000052113 | Ppp1r9b | 1-to-2 |
| Cow | bosTau6 | ENSBTAG00000024426 | PPP1R9A | 1-to-1 |
| Chicken | galGal4 | ENSGALG00000009686 | PPP1R9A | 1-to-4 |
| Chicken | galGal3 | ENSGALG00000009686 | PPP1R9A | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000061304 | ppp1r9a | 1-to-5 |
| Zebrafish | danRer10 | ENSDARG00000063580 | si:ch1073-219n12.1 | 1-to-5 |
| Zebrafish | danRer10 | ENSDARG00000071709 | ppp1r9bb | 1-to-5 |
| Zebrafish | danRer10 | ENSDARG00000074575 | si:ch211-269i23.2 | 1-to-5 |
| Zebrafish | danRer10 | ENSDARG00000079366 | ppp1r9ba | 1-to-5 |