DmeEX0006537 @ dm6

Exon Skipping

Gene

Description

The gene Spinophilin is referred to in FlyBase by the symbol DmelSpn (CG16757, FBgn0010905). It is a protein_coding_gene from Dmel. It has 12 annotated transcripts and 12 polypeptides (9 unique). Gene sequence location is 3L:2505245..2554292. Its molecular function is described by: neurexin family protein binding; actin filament binding. It is involved in the biological process described with: neuron projection development; negative regulation of presynaptic active zone assembly; calcium-mediated signaling; actin filament organization. 29 alleles are reported. The phenotypes of these alleles manifest in: presynaptic active zone; embryonic/larval neuromuscular junction. The phenotypic classes of alleles include: smell perception defective; behavior defective; viable; flightless; neuroanatomy defective; partially lethal - majority die. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.

Coordinates

chr3L:2511163-2512472:-

Coord C1 exon

chr3L:2512295-2512472

Coord A exon

chr3L:2511878-2511931

Coord C2 exon

chr3L:2511163-2511763

Length

54 bp

Sequences

Splice sites

3' ss Seq

ATTTGTTTTTATTTTCCCAGAGC

3' ss Score

8.45

5' ss Seq

AAGGTTTGT

5' ss Score

7.81

Exon sequences

Seq C1 exon

CCAACAAGAGGAGTACCTGCGCCGCACTCTCGACTATTCCGAGGACTCCACTCAGCCGGTTTCGGCCAACTCGAGTGTCTGCGAGGGACCCTCGAGTCCCGTCCAAGTGGAACATCCAATGGAGGTGGAGGCCACCCACTCGCAGGAGGTAGAGTCGCTCAAGCGGCTGCTACAGGAG

Seq A exon

AGCGAAATGGGTTGCCTGGTTAAAGAGGAGATTATTCAAAATCTTAAACGAAAG

Seq C2 exon

CTGGTCAAGCTCGAGACGACGGGCAATGAGAACGAGCTGCTTAGCGAGCGACTGCGGCAAAGCGAGCGGGAGCTGGGCAATATCCGGAAGGAGGCGGCCAACCTGCAGAACATGCTCCAGCAGTCGCAGGGTCAGTATATGGCGCTGGACAAGAAGTACAACAAGGCCAAGCGGCTGGTCAGGGAGTACCAGCAGCGAGAGCTGGACATGTGCCATCGCGAGGAGTTCTACCAGCAGCTGCTCCAGGAGAAGGACACCGAGTACAATGCGCTGGTGAAGAAGCTGAAGGATCGTGTGATTAATCTGGAACACGAGCTGCAGGAGACGCAGCGCAAGGCCGGTTTTCCAGTGGGCCTGCCCTACGATAGTGCCACTCTGAAGTTGACGCCCCAGATGATGCGTAAGACGCCGCCAAAGCCGCTCTTCCACAAGCTCGAGACGGAGCTGTCGGATACGGAGATATCAGATCTCTCACCCGACGGCGATGGCGTTAAGACAGC

VastDB Features

Vast-tools module Information

Secondary ID

FBgn0010905-'17-14,'17-13,19-14

Average complexity

ME(12_18-13_19[100=97])

Mappability confidence:

100%=100=100%

Protein Impact

Alternative protein isoforms (Ref)

No structure available

Features