Special

FBgn0027561 @ dm6

Biotype
protein_coding
Gene Symbol
CG18659
Description
This gene is referred to in FlyBase by the symbol DmelCG18659 (FBgn0027561). It is a protein_coding_gene from Dmel. It has 8 annotated transcripts and 8 polypeptides (6 unique). Gene sequence location is 2R:9123304..9132030. Its molecular function is described by: Rab GTPase binding; phosphatidylinositol phosphate binding; Rab guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: regulation of Rab protein signal transduction; endocytic recycling; endocytosis. 8 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period.
Coordinates
chr2R:9123304-9132030:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Exon Skipping
195
chr2R:9131164-9131358
-
99.03
85.5
0
Exon Skipping
33
chr2R:9126181-9126213
-
72.36
84.17
0
Exon Skipping
477
chr2R:9124744-9125220
-
35.7
96.53
0
Exon Skipping
136
chr2R:9127027-9127162
-
14.88
78.17
0
Intron Retention
60
chr2R:9128311-9128370
-
19.15
66.67
0
Intron Retention
1205
chr2R:9126214-9127418
-
15.3
52.03
0
Intron Retention
330
chr2R:9125221-9125550
-
19.41
53.54
0
Intron Retention
598
chr2R:9124146-9124743
-
18.27
74.19
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000119522 DENND1A 1-to-3
Human hg38 ENSG00000205744 DENND1C 1-to-3
Human hg38 ENSG00000213047 DENND1B 1-to-3
Human hg19 ENSG00000119522 DENND1A 1-to-3
Human hg19 ENSG00000205744 DENND1C 1-to-3
Human hg19 ENSG00000213047 DENND1B 1-to-3
Mouse mm10 ENSMUSG00000002668 Dennd1c 1-to-3
Mouse mm10 ENSMUSG00000035392 Dennd1a 1-to-3
Mouse mm10 ENSMUSG00000056268 Dennd1b 1-to-3
Mouse mm9 ENSMUSG00000002668 Dennd1c 1-to-3
Mouse mm9 ENSMUSG00000035392 Dennd1a 1-to-3
Mouse mm9 ENSMUSG00000056268 Dennd1b 1-to-3
Rat rn6 ENSRNOG00000010526 Dennd1a 1-to-3
Rat rn6 ENSRNOG00000011063 Dennd1b 1-to-3
Rat rn6 ENSRNOG00000046050 Dennd1c 1-to-3
Cow bosTau6 ENSBTAG00000003610 DENND1A 1-to-4
Cow bosTau6 ENSBTAG00000012433 DENND1B 1-to-4
Cow bosTau6 ENSBTAG00000031809 DENND1C 1-to-4
Cow bosTau6 ENSBTAG00000037661 1-to-4
Chicken galGal4 ENSGALG00000001157 DENND1A 1-to-2
Chicken galGal4 ENSGALG00000002246 DENND1B 1-to-2
Chicken galGal3 ENSGALG00000001157 DENND1A 1-to-2
Chicken galGal3 ENSGALG00000002246 DENND1B 1-to-2
Zebrafish danRer10 ENSDARG00000014592 DENND1A 1-to-3
Zebrafish danRer10 ENSDARG00000078503 DENND1C 1-to-3
Zebrafish danRer10 ENSDARG00000101868 dennd1b 1-to-3