DmeEX0001313 @ dm6
Exon Skipping
Gene
FBgn0027561 | CG18659
Description
This gene is referred to in FlyBase by the symbol DmelCG18659 (FBgn0027561). It is a protein_coding_gene from Dmel. It has 8 annotated transcripts and 8 polypeptides (6 unique). Gene sequence location is 2R:9123304..9132030. Its molecular function is described by: Rab GTPase binding; phosphatidylinositol phosphate binding; Rab guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: regulation of Rab protein signal transduction; endocytic recycling; endocytosis. 8 alleles are reported. No phenotypic data is available. No phenotypic class data is available. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period.
Coordinates
chr2R:9125551-9127877:-
Coord C1 exon
chr2R:9127419-9127877
Coord A exon
chr2R:9126181-9126213
Coord C2 exon
chr2R:9125551-9126066
Length
33 bp
Sequences
Splice sites
3' ss Seq
CGTCTGTCTAACCATTGCAGACT
3' ss Score
8.31
5' ss Seq
TCGGTGAGT
5' ss Score
11.11
Exon sequences
Seq C1 exon
GTCACCAGTGATGAGCTGGGTGAAGTTGTGATTCTGAACTGTGATACGAAAATATTCGAAAGCCCATTCGACGATGTGCACAATCTGCCAACGGAGATTGTGTCACAGCTGAAGAAGCATCTGAATCACACACATGACCACATCGGCGACCGCATCTCGAAGATCTTCCTAAACGCACTGGTGCAGCTCATCGGTGGCTACCGGGACGCTGTGGAGTACCACGAGAACAGCAAGACGTTTAATTCCCAAAAATTCATTGAATCTCGGCCGGCGCACCTGCGCCCCTTTCTTGCCAAAATGATGGATCTACAGATCTTTGCGCAGTTCATTGACGATCGCCTAACGATGCTCAACAGCGGACTCGGCTTCTCGGACGAGTTCGAGCTGGAGACGGTGCGCTATGCGGAAAAGAAGAAGCGCGGTCGAAACTACGCCATCATGAAGAACCTTAAGGACAAG
Seq A exon
ACTAATCCGGCTGTAAAGTCTGCCGTCAAATCG
Seq C2 exon
GTTAAGGAGGGCTCGCGGGGCATGAAGACCGCCTATAAGGGATTCAAGACAAAGCTGCGCGAGAACGGAAACCAGTTTGGTGGCACGCACTTCCACTTTGGACTTGGCTCCCCGAATCATTCGGATCGTCCTGACGGCACCAGCGGAGGATACGTTCGTGGTGGCAAGGCCATCGGGGCTGCACACCACTCGGCGCCCAGTTCTCCAGTGACCAGCAAGCGTCTTGATGGAATTGCCTCCGTCACGGGAAGCAGCGGCAGCGGTGGATCCGGCGCCAGGGAGCCGCGGGAGTTCCTGCGACGCGGTCCCGTCCCGCTGGCCATGTCTAGCTCGAGCAGCCACATTCAGCCGAACGGCCATGCGTACGGTGCGAGTGCTGGTGCTCATTATGGTCATCATCTCGCTGCGTCTCCTGCTGTTAGCTCGGCGAGCTCGCTCTGCTCATCTTCGGAGATGAACCTGTCGCAGGAACTGCAGAACCATCCGCTTTTCAAGACGCC
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0027561-'11-11,'11-10,14-11
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.020 A=0.727 C2=0.847
Domain overlap (PFAM):
C1:
PF0214116=DENN=PD(8.6=10.5),PF0345514=dDENN=WD(100=43.1)
A:
NO
C2:
NO
Main Inclusion Isoform:
FBpp0087707
Main Skipping Isoform:
FBpp0291659
Other Inclusion Isoforms:
FBpp0291660, FBpp0308463
Other Skipping Isoforms:
FBpp0297474
Associated events
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGAAGCGCGGTCGAAACTA
R:
CAAACTGGTTTCCGTTCTCGC
Band lengths:
128-161
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)