FBgn0033159 @ dm6
Biotype
protein_coding
Gene Symbol
Dscam1
Description
The gene Down syndrome cell adhesion molecule 1 is referred to in FlyBase by the symbol DmelDscam1 (CG17800, FBgn0033159). It is a protein_coding_gene from Dmel. It has 76 annotated transcripts and 76 polypeptides (75 unique). Gene sequence location is 2R:7317924..7381899. Its molecular function is described by: identical protein binding; antigen binding; protein homodimerization activity; axon guidance receptor activity; cell-cell adhesion mediator activity. It is involved in the biological process described with 16 unique terms, many of which group under: central nervous system development; response to other organism; cell-cell adhesion via plasma-membrane adhesion molecules; nervous system process; developmental growth. 159 alleles are reported. The phenotypes of these alleles manifest in: cell projection; plasma membrane bounded cell projection; neuron projection; mushroom body beta-lobe; larval neuromere. The phenotypic classes of alleles include: increased mortality; cell migration defective; phenotype; behavior defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages.
Coordinates
chr2R:7317924-7381899:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
---|---|---|---|---|
Human | hg38 | ENSG00000143341 | HMCN1 | 4-to-4 |
Human | hg38 | ENSG00000148357 | HMCN2 | 4-to-4 |
Human | hg38 | ENSG00000171587 | DSCAM | 4-to-4 |
Human | hg38 | ENSG00000177103 | DSCAML1 | 4-to-4 |
Human | hg19 | ENSG00000143341 | HMCN1 | 4-to-4 |
Human | hg19 | ENSG00000148357 | HMCN2 | 4-to-4 |
Human | hg19 | ENSG00000171587 | DSCAM | 4-to-4 |
Human | hg19 | ENSG00000177103 | DSCAML1 | 4-to-4 |
Mouse | mm10 | ENSMUSG00000032087 | Dscaml1 | 4-to-4 |
Mouse | mm10 | ENSMUSG00000050272 | Dscam | 4-to-4 |
Mouse | mm10 | ENSMUSG00000055632 | Hmcn2 | 4-to-4 |
Mouse | mm10 | ENSMUSG00000066842 | Hmcn1 | 4-to-4 |
Mouse | mm9 | ENSMUSG00000032087 | Dscaml1 | 4-to-4 |
Mouse | mm9 | ENSMUSG00000050272 | Dscam | 4-to-4 |
Mouse | mm9 | ENSMUSG00000055632 | Hmcn2 | 4-to-4 |
Mouse | mm9 | ENSMUSG00000066842 | Hmcn1 | 4-to-4 |
Cow | bosTau6 | ENSBTAG00000002319 | HMCN2 | 4-to-4 |
Cow | bosTau6 | ENSBTAG00000004754 | DSCAM | 4-to-4 |
Cow | bosTau6 | ENSBTAG00000015235 | HMCN1 | 4-to-4 |
Cow | bosTau6 | ENSBTAG00000016692 | DSCAML1 | 4-to-4 |
Chicken | galGal4 | ENSGALG00000007314 | DSCAML1 | 4-to-3 |
Chicken | galGal4 | ENSGALG00000016138 | DSCAM | 4-to-3 |
Chicken | galGal3 | ENSGALG00000007314 | DSCAML1 | 4-to-3 |
Chicken | galGal3 | ENSGALG00000016138 | DSCAM | 4-to-3 |
Zebrafish | danRer10 | ENSDARG00000016936 | hmcn1 | 4-to-6 |
Zebrafish | danRer10 | ENSDARG00000024865 | dscama | 4-to-6 |
Zebrafish | danRer10 | ENSDARG00000028118 | dscamb | 4-to-6 |
Zebrafish | danRer10 | ENSDARG00000079327 | hmcn2 | 4-to-6 |
Zebrafish | danRer10 | ENSDARG00000098057 | dscaml1 | 4-to-6 |