Special

FBgn0261046 @ dm6

Biotype
protein_coding
Gene Symbol
Dscam3
Description
The gene Down syndrome cell adhesion molecule 3 is referred to in FlyBase by the symbol DmelDscam3 (CG31190, FBgn0261046). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 3R:17473935..17505667. Its molecular function is described by: identical protein binding; cell-cell adhesion mediator activity. It is involved in the biological process described with: homophilic cell adhesion via plasma membrane adhesion molecules; axon guidance; dendrite self-avoidance. 17 alleles are reported. The phenotype of these alleles manifest in: commissure. The phenotypic classes of alleles include: viable; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed during early larval stages, at stages throughout the pupal period.
Coordinates
chr3R:17473935-17505667:-
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Alternative 3'ss
0
NA
-
48.02
96.55
0
Alternative 3'ss
89
chr3R:17474917-17475005
-
51.98
96.55
0
Alternative 5'ss
0
NA
-
23.12
56.41
0
Alternative 5'ss
9
chr3R:17475644-17475652
-
76.88
56.41
0
Exon Skipping
144
chr3R:17504040-17504183
-
94.89
21.05
0
Exon Skipping
220
chr3R:17497355-17497574
-
95.06
74.47
0
Intron Retention
1409
chr3R:17504184-17505592
-
26.05
92.59
0
Intron Retention
358
chr3R:17489928-17490285
-
8.05
47.83
0
Intron Retention
99
chr3R:17487891-17487989
-
9.29
80.33
0
Intron Retention
319
chr3R:17483942-17484260
-
18.17
52.73
0
Intron Retention
374
chr3R:17483448-17483821
-
8.09
27.27
0
Intron Retention
89
chr3R:17481650-17481738
-
8.52
36.72
0
Intron Retention
754
chr3R:17480752-17481505
-
7.84
32
0
Intron Retention
411
chr3R:17478699-17479109
-
7.57
35.74
0
Intron Retention
187
chr3R:17476708-17476894
-
10.63
51.69
0
Intron Retention
300
chr3R:17475344-17475643
-
18.89
23.09
0
Intron Retention
74
chr3R:17475006-17475079
-
24.78
55.5
0
Intron Retention
256
chr3R:17492180-17492435
-
10.87
89.04
0
Intron Retention
182
chr3R:17491848-17492029
-
8.96
63.82
0
Intron Retention
1323
chr3R:17490404-17491726
-
9.94
64.35
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000143341 HMCN1 4-to-4
Human hg38 ENSG00000148357 HMCN2 4-to-4
Human hg38 ENSG00000171587 DSCAM 4-to-4
Human hg38 ENSG00000177103 DSCAML1 4-to-4
Human hg19 ENSG00000143341 HMCN1 4-to-4
Human hg19 ENSG00000148357 HMCN2 4-to-4
Human hg19 ENSG00000171587 DSCAM 4-to-4
Human hg19 ENSG00000177103 DSCAML1 4-to-4
Mouse mm10 ENSMUSG00000032087 Dscaml1 4-to-4
Mouse mm10 ENSMUSG00000050272 Dscam 4-to-4
Mouse mm10 ENSMUSG00000055632 Hmcn2 4-to-4
Mouse mm10 ENSMUSG00000066842 Hmcn1 4-to-4
Mouse mm9 ENSMUSG00000032087 Dscaml1 4-to-4
Mouse mm9 ENSMUSG00000050272 Dscam 4-to-4
Mouse mm9 ENSMUSG00000055632 Hmcn2 4-to-4
Mouse mm9 ENSMUSG00000066842 Hmcn1 4-to-4
Rat rn6 ENSRNOG00000016502 Dscaml1 2-to-2
Rat rn6 ENSRNOG00000027992 Dscam 2-to-2
Cow bosTau6 ENSBTAG00000002319 HMCN2 4-to-4
Cow bosTau6 ENSBTAG00000004754 DSCAM 4-to-4
Cow bosTau6 ENSBTAG00000015235 HMCN1 4-to-4
Cow bosTau6 ENSBTAG00000016692 DSCAML1 4-to-4
Chicken galGal4 ENSGALG00000007314 DSCAML1 4-to-3
Chicken galGal4 ENSGALG00000016138 DSCAM 4-to-3
Chicken galGal3 ENSGALG00000007314 DSCAML1 4-to-3
Chicken galGal3 ENSGALG00000016138 DSCAM 4-to-3
Zebrafish danRer10 ENSDARG00000016936 hmcn1 4-to-6
Zebrafish danRer10 ENSDARG00000024865 dscama 4-to-6
Zebrafish danRer10 ENSDARG00000028118 dscamb 4-to-6
Zebrafish danRer10 ENSDARG00000079327 hmcn2 4-to-6
Zebrafish danRer10 ENSDARG00000098057 dscaml1 4-to-6