Special

FBgn0261397 @ dm6

Biotype
protein_coding
Gene Symbol
didum
Description
The gene dilute class unconventional myosin is referred to in FlyBase by the symbol Dmeldidum (CG2146, FBgn0261397). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 2R:7500147..7508625. Its molecular function is described by 8 unique terms, many of which group under: binding; protein binding; cytoskeletal protein binding; nucleoside-triphosphatase activity; catalytic activity. It is involved in the biological process described with 9 unique terms, many of which group under: organelle organization; establishment of protein localization; positive regulation of multicellular organismal process; cellular component organization or biogenesis; actin filament-based process. 24 alleles are reported. The phenotypes of these alleles manifest in: reproductive system; adult abdomen; male organism; plasma membrane bounded cell projection; peripheral nervous system. The phenotypic classes of alleles include: lethal - all die before end of embryonic stage; increased mortality; fertile; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.
Coordinates
chr2R:7500147-7508625:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Exon Skipping
98
chr2R:7505649-7505746
+
85.7
91.76
0
Exon Skipping
24
chr2R:7503172-7503195
+
39.71
98.59
0
Intron Retention
149
chr2R:7505500-7505648
+
8.35
100
0
Intron Retention
62
chr2R:7506787-7506848
+
3.7
77.27
0
Intron Retention
64
chr2R:7502738-7502801
+
7.32
100
0
Intron Retention
620
chr2R:7503029-7503648
+
20.84
100
0
Intron Retention
59
chr2R:7504716-7504774
+
8.53
54.1
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000128833 MYO5C 1-to-3
Human hg38 ENSG00000167306 MYO5B 1-to-3
Human hg38 ENSG00000197535 MYO5A 1-to-3
Human hg19 ENSG00000128833 MYO5C 1-to-3
Human hg19 ENSG00000167306 MYO5B 1-to-3
Human hg19 ENSG00000197535 MYO5A 1-to-3
Mouse mm10 ENSMUSG00000025885 Myo5b 1-to-3
Mouse mm10 ENSMUSG00000033590 Myo5c 1-to-3
Mouse mm10 ENSMUSG00000034593 Myo5a 1-to-3
Mouse mm9 ENSMUSG00000025885 Myo5b 1-to-3
Mouse mm9 ENSMUSG00000033590 Myo5c 1-to-3
Mouse mm9 ENSMUSG00000034593 Myo5a 1-to-3
Rat rn6 ENSRNOG00000008356 Myo5c 1-to-3
Rat rn6 ENSRNOG00000014104 Myo5b 1-to-3
Rat rn6 ENSRNOG00000058866 Myo5a 1-to-3
Cow bosTau6 ENSBTAG00000003763 MYO5C 1-to-3
Cow bosTau6 ENSBTAG00000006489 MYO5A 1-to-3
Cow bosTau6 ENSBTAG00000019455 1-to-3
Chicken galGal4 ENSGALG00000012984 MYO5B 1-to-3
Chicken galGal3 ENSGALG00000012984 1-to-3
Zebrafish danRer10 ENSDARG00000025218 myo5ab 1-to-6
Zebrafish danRer10 ENSDARG00000061635 myo5aa 1-to-6
Zebrafish danRer10 ENSDARG00000061810 si:dkey-110c1.10 1-to-6
Zebrafish danRer10 ENSDARG00000062003 myo5b 1-to-6
Zebrafish danRer10 ENSDARG00000104235 myo5c 1-to-6