BtaEX0012220 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000002646 | DYNC1I2
Description
cytoplasmic dynein 1 intermediate chain 2 [Source:RefSeq peptide;Acc:NP_001069351]
Coordinates
chr2:24838874-24846914:-
Coord C1 exon
chr2:24846824-24846914
Coord A exon
chr2:24841397-24841456
Coord C2 exon
chr2:24838874-24838989
Length
60 bp
Sequences
Splice sites
3' ss Seq
GTTGTCCTACAACCATTTAGGAC
3' ss Score
5.51
5' ss Seq
GGGGTATTG
5' ss Score
2.65
Exon sequences
Seq C1 exon
TCCCTCCTCCTATGTCTCCATCCTCCAAATCTGTGAGCACACCAAGCGAAGCTGGGAGCCAGGACTCTGGAGATGGCGCCGTGGGATCTAG
Seq A exon
GACGCTGCATTGGGATACAGATCCATCAGTTCTTCAGCTTCACTCAGATTCCGATTTGGG
Seq C2 exon
ACGAGGACCTATTAAACTTGGAATGGCTAAAATTACACAAGTTGACTTTCCTCCTCGTGAAATTGTCACATACACAAAGGAAACTCAGACTCCAGTTATGGCTCAACCCAAAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000002646_CASSETTE3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=1.000 C2=0.942
Domain overlap (PFAM):
C1:
PF115403=Dynein_IC2=PU(0.1=0.0)
A:
PF115403=Dynein_IC2=PU(0.1=0.0)
C2:
PF115403=Dynein_IC2=WD(100=82.5)
Main Inclusion Isoform:
ENSBTAT00000003429fB2306
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCTCCTCCTATGTCTCCATCC
R:
CGAGGAGGAAAGTCAACTTGTGT
Band lengths:
147-207
Functional annotations
There are 1 annotated functions for this event
PMID: 22749401
Inclusion decreases interaction with PAFAH1B1 and DYNC1I1, but not with NDEL1, DYNLRB1, DCTN1, DYNLT3, DCTN2, NR3C1. By LUMIER.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development