DreEX0028600 @ danRer10
Exon Skipping
Gene
ENSDARG00000078386 | dync1i2a
Description
dynein, cytoplasmic 1, intermediate chain 2a [Source:ZFIN;Acc:ZDB-GENE-060929-1086]
Coordinates
chr9:3177695-3182999:+
Coord C1 exon
chr9:3177695-3177785
Coord A exon
chr9:3181502-3181555
Coord C2 exon
chr9:3182884-3182999
Length
54 bp
Sequences
Splice sites
3' ss Seq
GTGTGTCGTGACACTAACAGGAC
3' ss Score
6.09
5' ss Seq
CGGGTACTG
5' ss Score
5.43
Exon sequences
Seq C1 exon
CTCCTGCACCCATGTCTCCCACTGCCAAATCTGTGGGCAGTCCAAGTGAGGCAGGGAGCCAAGACTCAGGAGACGGGACCACTGGACCACG
Seq A exon
GACTCTGCACTGGGACTGTGACCCGTCCACTGTTCTTCTTCACTCTGAGCTCGG
Seq C2 exon
ACGTGGTCCTCTGAAGTTGGCCATGACAAAGATGACCCATGTGGATTTCCCGCCAAAAGAGGTGGTGTCCTACACCAAAGAGACACAGACGCCCACCATGACCGAGCAGAAGGACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000078386-'4-7,'4-5,5-7
Average complexity
S
Mappability confidence:
89%=100=80%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=1.000 C2=0.984
Domain overlap (PFAM):
C1:
PF115403=Dynein_IC2=PU(0.1=0.0)
A:
PF115403=Dynein_IC2=PU(0.1=0.0)
C2:
PF115403=Dynein_IC2=WD(100=82.5)
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCATGTCTCCCACTGCCAAAT
R:
ACCTCTTTTGGCGGGAAATCC
Band lengths:
145-199
Functional annotations
There are 1 annotated functions for this event
PMID: 22749401
Inclusion decreases interaction with PAFAH1B1 and DYNC1I1, but not with NDEL1, DYNLRB1, DCTN1, DYNLT3, DCTN2, NR3C1. By LUMIER.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]