MmuEX0015954 @ mm10
Exon Skipping
Gene
ENSMUSG00000027012 | Dync1i2
Description
dynein cytoplasmic 1 intermediate chain 2 [Source:MGI Symbol;Acc:MGI:107750]
Coordinates
chr2:71228600-71236030:+
Coord C1 exon
chr2:71228600-71228690
Coord A exon
chr2:71233649-71233708
Coord C2 exon
chr2:71235915-71236030
Length
60 bp
Sequences
Splice sites
3' ss Seq
GTTGCCCTACAACCATTTAGGAC
3' ss Score
4.44
5' ss Seq
GGGGTATTG
5' ss Score
2.65
Exon sequences
Seq C1 exon
TCCCTCCTCCTATGTCTCCATCCTCCAAGTCGGTGAGCACGCCAAGTGAAGCTGGAAGCCAGGATTCTGGAGATGGCGCCGTGGGATCTAG
Seq A exon
GACGCTGCATTGGGATACAGATCCATCAGTTCTTCAGCTTCACTCAGATTCCGATTTGGG
Seq C2 exon
ACGAGGACCTATTAAACTTGGAATGGCCAAAATTACTCAAGTTGACTTTCCCCCTCGAGAAATCGTCACATACACAAAGGAAACTCAGACCCCGGTTACAGCTCAACCCAAAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027012_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=1.000 C2=0.940
Domain overlap (PFAM):
C1:
PF115403=Dynein_IC2=PU(0.1=0.0)
A:
PF115403=Dynein_IC2=PU(0.1=0.0)
C2:
PF115403=Dynein_IC2=WD(100=82.5)
Other Inclusion Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCATCCTCCAAGTCGGTGAG
R:
TCTCGAGGGGGAAAGTCAACT
Band lengths:
135-195
Functional annotations
There are 1 annotated functions for this event
PMID: 22749401
This event
Inclusion decreases interaction with PAFAH1B1 and DYNC1I1, but not with NDEL1, DYNLRB1, DCTN1, DYNLT3, DCTN2, NR3C1. By LUMIER.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types