DreEX0028593 @ danRer10
Exon Skipping
Gene
ENSDARG00000060948 | dync1i1
Description
dynein, cytoplasmic 1, intermediate chain 1 [Source:ZFIN;Acc:ZDB-GENE-061215-62]
Coordinates
chr16:25406235-25409992:+
Coord C1 exon
chr16:25406235-25406325
Coord A exon
chr16:25408990-25409049
Coord C2 exon
chr16:25409877-25409992
Length
60 bp
Sequences
Splice sites
3' ss Seq
TATTTTACTGACCTCTTCAGGAC
3' ss Score
8.27
5' ss Seq
TGGGTGAGA
5' ss Score
6.04
Exon sequences
Seq C1 exon
TCCCAACCCCTATGTCTCCCTCTTCGCAATCAGTGAGTCCACCCAGCGAAACTGGAAGCCAGGAGTCCATAGATGGAGGGACAGTGGAAAG
Seq A exon
GACGTTGCAGTGGGACACTGACCCCTCAGCTCTTCAGCTTCTTGCAGATTCTGTTCATGG
Seq C2 exon
GTGCAGGATGCAGAGGCTTGGAGCATCAAAAATTGTTCAGATTGATTTCATGCCAAAAGAGCTGGTGACATACTCTAAAGAGACACAGACCCCTGTCGCATCAAATCAGCCTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000060948-'4-8,'4-7,6-8
Average complexity
S
Mappability confidence:
89%=80=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=0.937 C2=0.425
Domain overlap (PFAM):
C1:
NO
A:
PF115403=Dynein_IC2=PU(0.1=0.0)
C2:
PF115403=Dynein_IC2=WD(100=82.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAATCAGTGAGTCCACCCAGC
R:
TGTCACCAGCTCTTTTGGCAT
Band lengths:
135-195
Functional annotations
There are 1 annotated functions for this event
PMID: 22749401
Inclusion decreases interaction with PAFAH1B1 and DYNC1I1, but not with NDEL1, DYNLRB1, DCTN1, DYNLT3, DCTN2, NR3C1. By LUMIER.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]