BtaEX6035020 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000002252 | CHRNA2
Description
cholinergic receptor, nicotinic, alpha 2 (neuronal) [Source:HGNC Symbol;Acc:HGNC:1956]
Coordinates
chr8:75874056-75883978:-
Coord C1 exon
chr8:75883934-75883978
Coord A exon
chr8:75879382-75879491
Coord C2 exon
chr8:75874056-75875070
Length
110 bp
Sequences
Splice sites
3' ss Seq
ACTCCCTTCCCCACGCACAGGAG
3' ss Score
6.95
5' ss Seq
CAAGTAGGA
5' ss Score
4.46
Exon sequences
Seq C1 exon
GATGAGAAGAACCAAATGATGACTACCAATGTCTGGCTAAAGCAG
Seq A exon
GAGTGGAGCGACTACAAGCTGCGCTGGAACCCGGTCGATTTCGGCAACATCACATCCCTCCGCGTCCCTTCGGAGATGATCTGGATCCCAGACATAGTCCTCTACAACAA
Seq C2 exon
TGCAGATGGGGAGTTTGTGGTGACCCACATGACCAAGGCCCACCTCTTCTCCTCGGGCCTGCTGCACTGGGCACCGCCTGCCATCTACAAGAGCTCCTGCAGCATCGACGTCACCTTCTTCCCCTTCGACCAGCAGAACTGCAAGATGAAGTTTGGCTCCTGGTCGTACGACAAGGCCAAGATCGACCTGGTGCAGATGGAGCAGACGGTGGACCTGAAGGACTACTGGGAGAGCGGCGAGTGGGCCATCGTCAACGCCACGGGCACCTACAACACCAAGAAGTACGACTGCTGCGCCGAGGTCTACGCCGACGTCACCTACTACTTCGTCATCCGGCGCCTGCCCCTGTTCTACACCATCAACCTCATCATCCCTTGCCTGCTCATCTCCTGCCTCACCGTGCTCGTCTTCTACCTGCCCTCCGACTGCGGCGAGAAGATCACCCTGTGCATCTCTGTGCTGCTCTCACTCACCGTCTTCCTGCTGCTCATCACCGAGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000002252-'4-7,'4-4,7-7=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.044
Domain overlap (PFAM):
C1:
PF0293118=Neur_chan_LBD=FE(6.8=100)
A:
PF0293118=Neur_chan_LBD=FE(17.4=100)
C2:
PF0293118=Neur_chan_LBD=PD(55.6=33.9),PF0293211=Neur_chan_memb=PU(86.7=63.7)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAGAAGAACCAAATGATGACTACCA
R:
CATCTGCACCAGGTCGATCTT
Band lengths:
242-352
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]