HsaEX6080108 @ hg19
Exon Skipping
Gene
ENSG00000120903 | CHRNA2
Description
cholinergic receptor, nicotinic, alpha 2 (neuronal) [Source:HGNC Symbol;Acc:1956]
Coordinates
chr8:27320496-27326896:-
Coord C1 exon
chr8:27326852-27326896
Coord A exon
chr8:27324746-27324855
Coord C2 exon
chr8:27320496-27321510
Length
110 bp
Sequences
Splice sites
3' ss Seq
AACTCCTTCCCCACACACAGGAG
3' ss Score
5.82
5' ss Seq
CAAGTAGGA
5' ss Score
4.46
Exon sequences
Seq C1 exon
GATGAGAAGAACCAAATGATGACCACCAACGTCTGGCTAAAACAG
Seq A exon
GAGTGGAGCGACTACAAACTGCGCTGGAACCCCACTGATTTTGGCAACATCACATCTCTCAGGGTCCCTTCTGAGATGATCTGGATCCCCGACATTGTTCTCTACAACAA
Seq C2 exon
TGCAGATGGGGAGTTTGCAGTGACCCACATGACCAAGGCCCACCTCTTCTCCACGGGCACTGTGCACTGGGTGCCCCCGGCCATCTACAAGAGCTCCTGCAGCATCGACGTCACCTTCTTCCCCTTCGACCAGCAGAACTGCAAGATGAAGTTTGGCTCCTGGACTTATGACAAGGCCAAGATCGACCTGGAGCAGATGGAGCAGACTGTGGACCTGAAGGACTACTGGGAGAGCGGCGAGTGGGCCATCGTCAATGCCACGGGCACCTACAACAGCAAGAAGTACGACTGCTGCGCCGAGATCTACCCCGACGTCACCTACGCCTTCGTCATCCGGCGGCTGCCGCTCTTCTACACCATCAACCTCATCATCCCCTGCCTGCTCATCTCCTGCCTCACTGTGCTGGTCTTCTACCTGCCCTCCGACTGCGGCGAGAAGATCACGCTGTGCATTTCGGTGCTGCTGTCACTCACCGTCTTCCTGCTGCTCATCACTGAGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000120903-'12-18,'12-17,13-18=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.095 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0293118=Neur_chan_LBD=FE(14.6=100)
A:
PF0293118=Neur_chan_LBD=FE(18.8=100)
C2:
PF0293118=Neur_chan_LBD=PD(59.9=33.9),PF103294=DUF2417=WD(100=49.6),PF0293211=Neur_chan_memb=PU(86.7=63.7)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCAAATGATGACCACCAACGT
R:
CACAGTCTGCTCCATCTGCTC
Band lengths:
246-356
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)