MmuEX6042224 @ mm10
Exon Skipping
Gene
ENSMUSG00000022041 | Chrna2
Description
cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) [Source:MGI Symbol;Acc:MGI:87886]
Coordinates
chr14:66143921-66149819:+
Coord C1 exon
chr14:66143921-66143965
Coord A exon
chr14:66146406-66146515
Coord C2 exon
chr14:66148787-66149819
Length
110 bp
Sequences
Splice sites
3' ss Seq
GTGACCACTCCCCTGAGCAGGAA
3' ss Score
4.77
5' ss Seq
CAAGTAAGA
5' ss Score
7.61
Exon sequences
Seq C1 exon
GATGAGAAGAATCAAATGATGACCACCAATGTCTGGCTAAAGCAG
Seq A exon
GAATGGAATGACTACAAGCTGCGCTGGGACCCGGCTGAGTTTGGCAACATCACCTCCCTCCGCGTCCCCTCAGAGATGATCTGGATCCCAGACATTGTTCTCTACAACAA
Seq C2 exon
TGCAGACGGGGAGTTTGCGGTGACCCACATGACCAAGGCCCACCTCTTCTTCACGGGCACTGTGCACTGGGTGCCCCCAGCCATCTACAAGAGCTCCTGCAGCATCGACGTGACTTTCTTCCCCTTCGACCAGCAGAACTGCAAGATGAAGTTTGGCTCCTGGACATACGACAAGGCCAAGATCGACCTGGAGCAGATGGAGCGGACGGTGGACCTGAAGGACTACTGGGAGAGCGGCGAGTGGGCCATTATCAACGCCACCGGAACCTATAACAGCAAGAAGTACGACTGCTGCGCGGAGATCTACCCCGACGTCACCTACTACTTCGTTATCCGCCGGCTGCCGCTGTTCTACACCATCAACCTCATTATCCCGTGCCTGCTCATCTCCTGCCTCACCGTGCTCGTGTTCTACTTGCCCTCTGAGTGTGGAGAGAAGATCACGCTGTGCATCTCGGTGCTGCTCTCCCTCACTGTCTTCCTGCTGCTCATCACAGAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000022041-'1-7,'1-6,6-7=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.081
Domain overlap (PFAM):
C1:
PF0293118=Neur_chan_LBD=FE(6.8=100)
A:
PF0293118=Neur_chan_LBD=FE(17.4=100)
C2:
PF0293118=Neur_chan_LBD=PD(55.6=33.3),PF103294=DUF2417=WD(100=50.4),PF0293211=Neur_chan_memb=PU(87.1=64.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAAATGATGACCACCAATGTCTG
R:
TAGTCCTTCAGGTCCACCGTC
Band lengths:
258-368
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types