BtaEX6064467 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000020053 | ZEB1
Description
zinc finger E-box binding homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11642]
Coordinates
chr13:34063899-34075815:-
Coord C1 exon
chr13:34075710-34075815
Coord A exon
chr13:34066103-34067913
Coord C2 exon
chr13:34063899-34064079
Length
1811 bp
Sequences
Splice sites
3' ss Seq
AACTTTTTGTTGTTGTTTAGGAG
3' ss Score
7.51
5' ss Seq
CAGGTAAAA
5' ss Score
8.59
Exon sequences
Seq C1 exon
AGACATGTGACGCAGTCTGGGGGTAATCGTAAATTCAAGTGCACTGAATGTGGAAAAGCTTTCAAATACAAACACCATCTAAAAGAGCACTTAAGAATCCACAGTG
Seq A exon
GAGAGAAGCCATATGAATGCCCAAACTGCAAGAAACGTTTTTCCCATTCTGGTTCCTACAGCTCACACATAAGCAGTAAGAAATGTATCAGCCTGATGCCTGTGAACGGGCGACCAAGAACAGGGCTCAAGACCTCGCAGTGCTCCTCACCCTCGCTCTCGGCCTCTCCAGGCAGCCCCACGCGACCACAGATGCGGCAGAAGATAGAGAACAAGCCCCTGCAGGAGCAGCTCCCCGTAAACCAGATTAAAACTGAACCTGTGGATTATGAGTTCAAACCCATAGTGGTTGCTTCAGGAATCAACTGTTCAGCCCCTCTACAGAACGGGGTTTTCAGTGGTGGTGGCCCCTTACAGGCAACCAGTTCTCCTCAGGGTGTGGTGCAGGCCGTCGTTCTGCCAACGGTGGGTTTGGTGTCCCCCATCAGTATCAATTTAAGTGATATTCAGAATGTACTTAAAGTGGCGGTAGATGGTAACGTCATCAGGCAAGTTTTGGAGAATAATCAAGCCAATCTTGCATCCAAAGAACAAGAAACAATCAATGCTTCATCCATCCAGCAAGGCGGCCATTCTGTTATTTCAGCCATCAGTCTTCCTCTGGTTGATCAAGATGGAACCACCAAAATCATCATTAACTACAGTCTTGAACAACCTAGCCAACTTCAAGTTGTTCCTCAGAATTTAAAAAAAGAAACCCCAGTCCCCACCACCAATTGCAAAAGCGAAAAGTTACCAGAAGATCTTACTGTCAAGTCTGAGAAGGACAAAAGCTTTGAAGGGGGAGGGAACGACAGCACGTGCCTCCTGTGTGACGACTGTCCCGGGGACCTCAATGCACTTCCGGAGCTAAAGCACTATGACCTGAAGCAGCCCGCCCAGCCCCCTCCGCCCCCTACCCCAGAAGCTGCCAAGCCGGAGGCCGCCGCTTCATCGGGGTCCGGAGATGGCAGTTTGTCTCCCAGTCAGCCACCTTTAAAGAACCTCTTGTCTCTTCTGAAAGCATATTATGCTTTGAACGCACAACCAAGTGCAGAAGAGCTCTCAAAAATTGCCGATTCCGTGAACCTACCACTGGATGTAGTGAAAAAGTGGTTTGAAAAGATGCAAGCGGGACAGATCTCAGTGCAGTCTTCTGAACCATCTTCCCCGGAACCAGGCAAAGCCAACACCCCTGCCAAGAGCAACGATCAGCCTCAGGCTGCAGATGCAGATGAAGCCCAGGACAGCACAGGGAACCGCCAGAGCCCTCTGAAGAGAGCTAGCTCTCCCGTCTTACCAGGGGGCTCGGCCGTCAATGGTTCCAGAAGCAGCGCCTCCTCCCCTTCCCCCTTGAACCTCTCTTCCTCCAGAAGCGCACAGGGTTACTCATACCCAACAGAAGGGGCGCAGGAAGAGCCGCAGGTCGAACCTCTTGATCTTTCACTACCAAAGCAGCAGGGCGAGTTATTGGAAAGGCCAACTATCACTAGTGTTTACCAGAACAGTGTTTATTCTGTCCAGGAAGAACCCTTGAACTTGTCTTGTGCAAAAAAGGAGCCACAAAAGGACAGTTGTGTTACAGACTCAGAACCAGTTGTAAATGTAATCCCACCAAGTGCCAACCCCATAAATATTGCTATACCTACCGTCACTGCCCAGTTACCCACGATCGTGGCCATCGCTGACCAGAACAGTGTTCCGTGCTTGCGAGCACTGGCTGCCAACAAGCAGACCATCCTGATCCCCCAGGTTGCCTACACATACTCGACTGCAGTCAGCCCGGCGGTCCAGGAAACACCCTTGAAGGTGATCCAGCCCAGTGGAAATCAG
Seq C2 exon
GATGAAAGGCAAGACACTAGCTCAGAAGGAGTATCCAACGTAGAGGATCAGAACGACTCCGATTCCACGCCCCCCAAAAAGAAAATGCGGAAGACAGAAAACGGAATGTATGCTTGTGATTTGTGTGATAAGATATTCCAAAAGAGTAGCTCACTGTTGAGACATAAATACGAACACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000020053-'15-22,'15-20,16-22=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.194 A=0.523 C2=0.623
Domain overlap (PFAM):
C1:
PF134651=zf-H2C2_2=PU(38.5=27.8)
A:
PF134651=zf-H2C2_2=PD(57.7=2.5),PF0004624=Homeobox=WD(100=8.1)
C2:
PF134651=zf-H2C2_2=PU(38.5=16.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGCAGTCTGGGGGTAATCG
R:
CTGTGTGTTCGTATTTATGTCTCA
Band lengths:
278-2089
Functional annotations
There are 1 annotated functions for this event
PMID: 10567582
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: two hybrid. ELM ID: ELMI000085; ELM sequence: PLDLS; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]