DreEX6069569 @ danRer10
Exon Skipping
Gene
ENSDARG00000013207 | zeb1b
Description
zinc finger E-box binding homeobox 1b [Source:ZFIN;Acc:ZDB-GENE-010621-1]
Coordinates
chr12:26666549-26669101:-
Coord C1 exon
chr12:26668990-26669101
Coord A exon
chr12:26666819-26668503
Coord C2 exon
chr12:26666549-26666729
Length
1685 bp
Sequences
Splice sites
3' ss Seq
GTTCATTTTGTGTTGTGCAGGAG
3' ss Score
7.2
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
Exon sequences
Seq C1 exon
CGGCATGTTACTCAGTCAGGTGGAGGAGGGAATCGAAAGTTTAAATGCACTGAATGTGGCAAAGCCTTCAAGTACAAACACCACCTGAAAGAACACCTGCGCATCCACAGTG
Seq A exon
GAGAAAAGCCTTATGAATGCTCCAACTGCAAGAAGCGTTTCTCTCATTCCGGTTCCTACAGTTCCCACATAAGCAGTAAGAAGTGCATTGGTCTCATCTCAGTAAATGGACGACCACGACCTTCTCCTGCTACAGGGGCTGCCAAGACCCCGCAGTGCTCTTCCCCGTCCCTGCCAACCTCCTCCCCTACAGCACGAGTCCAAGTAAGAGACAAACTGGATAACAGCAAACCCCTTCAAGAGCAGCTTCCCTTGACACAGATCAAGTCTGAGCCGCTGGACTATGAGTACAAGCCTGTGGTAGTGGCCCCATCTGCTAGAGGCGTAAATGGCATGTTTCAGGGTGGGGCAGCAGCCCCTCTCCAGGGTGCCGTACAGGCTGTTGTGCTTCCAACTGTGGGACTGGTGTCCCCAATCAGCATCAATCTGGGGGACTTACAAAACGTGCTAAAGGTGGCAGTGGATGGGAATGTCATTAGGCAAGTGCTGGAAAGCACACAAGCTAAGGGGCAACAAGCAGGGACGGGGATTGTAGGAGCAGGAGGGATTGCCCAAGCTACCCAGCAAGTTATCCAAGCCATTAGTCTTCCTATCTTGGATCAGGATGGCAATGCTAAAATCTTCATCAACTATAGTCTGGACCCATCCCAAGCCCAAGCAGTCCTTCAAAGTCCAAAAAAGGAACCATTGGGGTCGAACACTGAGGTCTGCAAGGGTCAGAAGCTGCCTGAGGACCTTACAGTAAAGACAAATAGGGACAAAACCACCCTCACTGTGGATGAGAAGAGCATGTTACACAATGACATATTACTTAAGCACTGTGGTAAAGATGAACATAGGATTAACGGGAAAAATCTTGAGGAGAAGATGGACTTGGAAGGACTGTGTCCTGGTCAGCCTCCTCTGAAGAACCTTCTCTCCTTGCTCAAGGCTTACTTTGCCTTAAACAATGAACCCACTAAGGAGGAGCTGGCAAAGATATCGGAGTCTGTCAGTCTTCCAGCAGAGGTGGTGAAAAAGTGGTTTGAGAAGATGCAGCTGGGACAGATCTCCATAGACCCTTCTTCACCTCAGCATGAGGAGGAGCAAACCACTCCTGTGGATTTGGATGGTACTAAAGGTGCATCACCCAAACCAGACTTAGATGAGCAAATTAACTCAGAGAAGCAAGAGGAGAGGGAGTGCTGTAGCCCAGCGGAGGGCATTGCAGCCAGTGTGAATGGAATCGAGAGTGTCCCTGCATCCCCTTCACCACTAAACCTATCGGCTGATGGTCCTGTCCCAGCCAGGACTCTTGAGGAAGGCGAGGGACCTCTCGATCTGTCGCTACCAAAATCCGCTACTACAGCCTCTGTGGCTAGCGGTCATGCTAACACTGTTTACTCGGCTCAAGAGGAGCCGCTGAATTTGACTTGCACAAAGAAGGAACTGCTCAGTAATGCAAGCACCAATGCTGCCATATATGCCAGCCAACCAAGTGCCAATCCCATAAACATCATGACCACTCAACTGCCCACCCTAGTGGCTATCACTGACCAGGGACAGGCGCAATGTCTACGTGCACTTACCACCACTAAACAGACCATCCTGATCCCGCAGCTGACTTACAGTTATACCACTACATCCTCCAGCCCGGCAGGGACCGACACACCACAGAAGAACATTTTACATGTCAATGGCATCAAG
Seq C2 exon
GAGGAAAAACAGGAGATGGGGTCAGAGGCCACCTCTATATTGGAAGAACAGACAGACTCAGACTCAGGGCCGACCAAGAAGAAGATGAAAAGGACGGAGAGTGGGCTGTATGCCTGTGACCTGTGTGACAAAATCTTCCAGAAGAGCAGCTCGTTGCTCCGCCATAAATATGAACACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000013207-'10-8,'10-7,11-8=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.211 A=0.463 C2=0.590
Domain overlap (PFAM):
C1:
PF134651=zf-H2C2_2=PU(38.5=26.3)
A:
PF134651=zf-H2C2_2=PD(57.7=2.7),PF0004624=Homeobox=WD(100=8.4)
C2:
PF134651=zf-H2C2_2=PU(38.5=16.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGCATGTTACTCAGTCAGGT
R:
TGTGTGTTCATATTTATGGCGGA
Band lengths:
292-1977
Functional annotations
There are 1 annotated functions for this event
PMID: 10567582
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: two hybrid. ELM ID: ELMI000085; ELM sequence: PLDLS; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]