MmuEX6000055 @ mm10
Exon Skipping
Gene
ENSMUSG00000024238 | Zeb1
Description
zinc finger E-box binding homeobox 1 [Source:MGI Symbol;Acc:MGI:1344313]
Coordinates
chr18:5761328-5770564:+
Coord C1 exon
chr18:5761328-5761433
Coord A exon
chr18:5766221-5768025
Coord C2 exon
chr18:5770384-5770564
Length
1805 bp
Sequences
Splice sites
3' ss Seq
GCTGTTTTGTTGTTGTTTAGGAG
3' ss Score
7.62
5' ss Seq
CAGGTTAGT
5' ss Score
8.02
Exon sequences
Seq C1 exon
AGACATGTGACACAGTCTGGGGGAAACCGCAAGTTCAAGTGCACTGAATGCGGGAAGGCCTTCAAGTACAAACACCACCTGAAAGAGCACTTACGGATTCACAGTG
Seq A exon
GAGAGAAGCCATACGAATGCCCGAACTGCAAGAAACGGTTTTCCCATTCTGGCTCCTATAGCTCACATATAAGCAGTAAGAAGTGTATTAGCTTGATGCCTGTGAATGGCAGGCCTAGATCAGGACTCAAGACATCTCAGTGTTCCTCGCCATCTCTTTCGACATCACCAGGCAGTCCCACACGCCCACAGATACGACAGAAGATAGAGAATAAACCCCTTCAAGAACCGCTTTCTGTAAACCAAATCAAAACTGAACCTGTGGATTATGAGTTCAAACCCATAGTGGTTGCTTCAGGAATCAACTGTTCAACCCCTTTACAAAATGGGGTTTTTAGCAGTGGTGGCCAATTGCAGGCAACCAGTTCTCCTCAGGGTGTGGTGCAAGCCGTTGTTCTGCCAACAGTTGGTTTGGTATCTCCCATAAGTATCAACTTAAGTGACATTCAGAATGTACTTAAAGTGGCTGTAGATGGTAACGTAATACGACAAGTCTTGGAGACTAATCAAGCCAGTCTTGCATCCAAAGAGCAAGAAGCAGTGAGTGCTTCGCCCATCCAGCAGGGTGGCCATTCTGTCATTTCTGCCATCAGTCTTCCTTTAGTTGATCAGGATGGAACAACCAAAATCATCATCAACTACAGTCTTGAGCAGCCCAGTCAACTTCAGGTTGTTCCCCAGAATTTAAAGAAAGAAATCCCAGCCCCTACAAACAGCTGCAAAAGTGAGAAGTTACCAGAAGACCTTACTGTCAAATCAGAAACGGACAAAAGCTTTGAGGGGGCCAGGGATGATAGCACTTGCCTTCTGTGTGAGGACTGCCCAGGGGACCTCAATGCACTTCCAGAACTAAAGCACTATGACCCAGAGTGCCCTGCTCAGCCTCCACCCCCTGCCCCAGCCACCGAGAAGCCAGAGTCCTCTGCTTCATCAGCTGGAAACGGAGATTTGTCTCCCAGTCAGCCACCTTTAAAGAACCTTCTGTCACTCTTGAAAGCCTACTATGCTCTGAACGCGCAGCCAAGCACAGAAGAGCTCTCAAAGATCGCCGATTCTGTGAACCTACCGCTGGATGGAGTTAAAAAGTGGTTTGAAAAGATGCAAGCTGGACAGATTCCAGGACAGTCTCCTGACCCCCCTTCTCCTGGAACCGGGTCAGTAAACATACCTACAAAAACCGATGAGCAGCCTCAACCTGCGGATGGAAATGAGCCCCAGGAAGACAGCACACGCGGACAGAGTCCTGTCAAGATAAGGAGCTCTCCGGTTTTACCTGTAGGATCAGCCATGAACGGTTCCAGAAGCTGCACATCATCCCCATCCCCTCTAAACCTTTGCTCAGCCAGGAACCCGCAGGGTTACTCTTGTGTGGCAGAGGGTGCCCAGGAGGAGCCCCAAGTAGAACCTCTTGATCTCTCACTACCAAAGCAACAGGGAGAGTTACTGGAAAGGTCGACAGTCAGTAGCGTTTACCAGAACAGTGTTTATTCTGTCCAGGAAGAACCCTTGAACTTGTCTTGTGCAAAAAAGGAACCACAAAAGGACAGCTGTGTTACAGACTCAGAACCAGTTGTAAATGTAGTCCCACCAAGTGCCAACCCCATAAACATTGCTATTCCTACAGTCACTGCCCAGTTACCCACAATCGTGGCCATTGCTGACCAGAACAGTGTTCCATGTTTAAGAGCACTGGCCGCCAACAAGCAGACTATTCTGATTCCCCAAGTGGCATATACATATTCAGCTACTGTGAGCCCTGCCGTGCAGGAGCCGCCAGTGAAGGTGATCCAGCCAAACGGAAACCAG
Seq C2 exon
GATGAAAGACAAGACACTAGCTCAGAAGGAGTCTCCACTGTGGAGGACCAGAATGACTCTGACTCCACGCCACCCAAAAAGAAAACTCGGAAGACAGAGAATGGAATGTATGCATGTGACCTGTGTGACAAGATATTTCAGAAGAGCAGCTCACTGTTGAGACACAAATATGAGCACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024238_MULTIEX1-9/9=8-C2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.167 A=0.482 C2=0.623
Domain overlap (PFAM):
C1:
PF134651=zf-H2C2_2=PU(38.5=27.8)
A:
PF134651=zf-H2C2_2=PD(57.7=2.5),PF0004624=Homeobox=WD(100=8.1)
C2:
PF134651=zf-H2C2_2=PU(38.5=16.4)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACATGTGACACAGTCTGGGG
R:
CTGTGTGCTCATATTTGTGTCTCA
Band lengths:
286-2091
Functional annotations
There are 1 annotated functions for this event
PMID: 10567582
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: two hybrid. ELM ID: ELMI000085; ELM sequence: PLDLS; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types