DmeALTD0002683-1/2 @ dm6
Alternative 5'ss
Gene
FBgn0259734 | CG42388
Description
The gene Nostrin is referred to in FlyBase by the symbol DmelNost (CG42388, FBgn0259734). It is a protein_coding_gene from Dmel. It has 7 annotated transcripts and 7 polypeptides (5 unique). Gene sequence location is X:9030205..9054575. Its molecular function is described by: phospholipid binding; lipid binding. It is involved in the biological process described with: plasma membrane organization; imaginal disc-derived wing hair organization; plasma membrane tubulation; germarium-derived female germ-line cyst encapsulation; regulation of adherens junction organization. 40 alleles are reported. The phenotype of these alleles manifest in: wing hair. The phenotypic classes of alleles include: fertile; flight defective; lethal - all die during embryonic stage; lethal; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in adult female stages.
Coordinates
chrX:9042644-9050935:+
Coord C1 exon
chrX:9042644-9042791
Coord A exon
NA
Coord C2 exon
chrX:9049250-9050935
Length
0 bp
Sequences
Splice sites
5' ss Seq
TCGGTAAAT
5' ss Score
6.8
3' ss Seq
GTGTCCCATAAATCGAACAGCCG
3' ss Score
2.27
Exon sequences
Seq C1 exon
CGTTGTTGACGTCGCATCGTCGACGACGTTGCTCCCCCGTCGCTGTTCTAAATTTAGTCACCGACGCGTTTCTGTAAATGTCGCCGCTGCCGCCGTCTACAAATAACAATAATATTAGCAACAATAATTACAGTTTTATTTATTTTCG
Seq A exon
NA
Seq C2 exon
CCGTCAAAGATGAACCACCTGCGGGTGCACAAATTCAAGCTGGGCGGCAAAGATAATGCCGCCATGGCCGATTTGCCCCAATCGGAAAACACCACCAACAATAACAATAATATCGGAAGCAATAATAATCAAAAAGGCGGTGCAAAAGGATTTCTGGGAAGGATTAAGCGCTACTCAGTGTTGGGAAATAAACTGGGACGTCGTAATCTCGGCAGTATGAATTTGAATCCGCCGAATAATGTCGTTGATAATTCCGTTTCGCCCACTAAACTCCATACTGGAAGCTACAATATGACCGGTAGCCATTCCGATGATCATCGCCTGGAAATCGGAGCTCCGATTTTAATATCGACTACAACATTGGACACCGACCGTTTCGATGTCACGGAGGCGAGACTCAAACAGATTGGCGGCGGCATAGCCCAGACCTCCAGTATAGTAAGAACCCTGACGCCCAGGAGTTCGGATGAGGAGGAGTTTGTGGACGCCAGGAGTAGTCC
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0259734-6-7,7-7-1/2
Average complexity
Alt5
Mappability confidence:
NA
Protein Impact
5' UTR
No structure available
Features
Disorder rate (Iupred):
C1=NA A=NA C2=0.710
Domain overlap (PFAM):
C1:
NA
A:
NA
C2:
PF0061118=FCH=PU(5.6=0.9)
Main Inclusion Isoform:
NA
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Human
(hg38)
No conservation detected
Human
(hg19)
No conservation detected
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGTTTCTGTAAATGTCGCCGC
R:
CAGCTTGAATTTGTGCACCCG
Band lengths:
124-163
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)