DmeEX6013132 @ dm6
Exon Skipping
Gene
FBgn0034893 | mRpL43
Description
The gene mitochondrial ribosomal protein L43 is referred to in FlyBase by the symbol DmelmRpL43 (CG5479, FBgn0034893). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2R:23698105..23699014. Its molecular function is described by: structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation. 6 alleles are reported. The phenotype of these alleles manifest in: trichogen cell. The phenotypic classes of alleles include: visible; lethal - all die during larval stage; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early larval stages.
Coordinates
chr2R:23698105-23699014:+
Coord C1 exon
chr2R:23698105-23698360
Coord A exon
chr2R:23698423-23698529
Coord C2 exon
chr2R:23698595-23699014
Length
107 bp
Sequences
Splice sites
3' ss Seq
TCATACGAAACGTTCAATAGCGA
3' ss Score
1.84
5' ss Seq
ACTGTACGT
5' ss Score
6.33
Exon sequences
Seq C1 exon
GCTAACTCGTCATCTCTGGTCAGAGAGAATCAGCTGTTTGCGGCATGCTATTACGTCGTCTCTTATTTGGAATTGTAAAAAATAGTTAAAAATTGTTTTGAATTAAAAACAAATACAGAATGTCAAACAGCCACTTGTTCTTGAAGTCCGGCTTCCCCCGTGCACCCCTGCAAAATGGATTGGGACGCTATGTTTGTCAGCTCCAGCGGATCACCCTGAAGTTCTGCAAGAATAATGGATCCAGCAGAGGCATGCG
Seq A exon
CGACTTCATTGAGAATCACTTGCTGGACTTTGCCAAAGAGAATCCCGGGATTGTGGTCTATGTGAAGCCCAGGCGCCACCGCACGCCAGTTTTGGTGGGAGAGTACT
Seq C2 exon
TGAACGGCGAGCGCGAATGGATGAGCTGCAGGAACAGCACCCAAGAGGAGATCTCCAAGTGGATTGACCTGCTAAAGACTCAAAACGGCAGCTCCAGCTCCCTGCGACTCCGGAAAATGTGGCATACCGAAGTGCCCTCCATCCAAGGCCCGTGGACGCCATTCCTGCTGCGTTCGCCGGATGCCCAAGGCCAGGCTTACCCCAGTGCCGAGGCGTCAAAGCCGCTGGATACGCCGCAAACTGCCACCGAGAAGCTCATCGAGTTGTTCCGGCAACAGCAACTGGAAGCTGGCGAGGAAGCACACGACGTGCTGAACAAAAAGCGGGCCGAGTGATAGGGATTAGGACTTTTTGGTAATTGTTGCTTTTATTTTTATAGTCAACATAGTTTTGTTGGTAAACAAATAAATATTTAAAATC
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0034893-'0-1,'0-0,1-1=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.405
Domain overlap (PFAM):
C1:
PF0504711=L51_S25_CI-B8=PU(1.9=2.2)
A:
PF0504711=L51_S25_CI-B8=FE(69.2=100)
C2:
PF0504711=L51_S25_CI-B8=PD(26.9=12.5)
Main Inclusion Isoform:
FBpp0071993
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGCATGCTATTACGTCGTCT
R:
TTCCTGCAGCTCATCCATTCG
Band lengths:
250-357
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)