DmeEX6017256 @ dm6
Exon Skipping
Gene
FBgn0036741 | CG7510
Description
The gene anchor is referred to in FlyBase by the symbol Dmelanchor (CG7510, FBgn0036741). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:17621824..17630971. Its molecular function is unknown. It is involved in the biological process described with: transmembrane transport; intracellular signal transduction. 9 alleles are reported. The phenotypes of these alleles manifest in: syncytium; cell; dorsal-ventral compartment boundary of imaginal disc; wing posterior compartment; wing disc posterior compartment. The phenotypic classes of alleles include: lethal - all die before end of larval stage; increased mortality during development; increased mortality; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in stages of adults of both sexes.
Coordinates
chr3L:17626693-17627554:+
Coord C1 exon
chr3L:17626693-17627024
Coord A exon
chr3L:17627087-17627252
Coord C2 exon
chr3L:17627315-17627554
Length
166 bp
Sequences
Splice sites
3' ss Seq
CGTGTACTCTCATTTCACAGATT
3' ss Score
10.18
5' ss Seq
TTGGTAATT
5' ss Score
5.73
Exon sequences
Seq C1 exon
ACCCGCAATCCACCATTGTGTCCAGAAACTTGTCCCGCGGAACAGATGTCCAAACGGAATCGCTGCCTGGGTGAACGGTCTATACTGGTTTTCAACACCCTAATTGCACTGTTCTTTAACCCGTTGCTGCTGATGACCTTGCTGGGTGTTGCAGGAGGATTCCTGTTTCCCAACGGTCTGCCCGAAATGGTGTCCAGTACGTTGCGTGTTCTTGGCCAGAGCTTTTCGGCAACGGCCTTGTTCCTACTCGGTCTTAAGATCGTAGGTGGGACAGGATCCGAACGAAAGAGTATAGGCTTTCTATTGCCTGGTGTTCTTATACTGGTTAAAAT
Seq A exon
ATTGGTGCTACCGCTCGTAATCCGACAGACGGTAAACATTATGCAGTCTGGCCAGAACTTCAACGACACCACCGAGCTGAGCACTTTTGGCTTTCTCTACGGCACCTTTCCAGCTGCCCCCGGGGCTTTCGTCATTGCGACACAGTACAACATGGAGGTTGAATTG
Seq C2 exon
GTTGCTCGAAGCATGGTTTTCTGTACATTCATCTCGGCACCGCTGATGTTTATATCAGCCAAAATGATATCGCTGACGAACCTGAAGCCATTGGACTATCTCCATGAGCTGGATGCCTTTTCGTTTGACATCAGCGTGGCCGGCGCGGCTGCCTGTTGTATCATGCTGGCATTGTTGATCGTGACGAAGCGCTTCAAGCGTATGCCCCAAAGAATAACTTTCTGTCTGGTGCTTTCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
FBgn0036741-'5-4,'5-3,6-4=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.027 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0354713=Mem_trans=FE(32.1=100)
A:
PF0354713=Mem_trans=FE(16.0=100)
C2:
PF0354713=Mem_trans=PD(5.2=22.5)
Main Inclusion Isoform:
FBpp0305332

Main Skipping Isoform:
NA
Other Inclusion Isoforms:
FBpp0074947
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGGGTGTTGCAGGAGGATTC
R:
ATAAACATCAGCGGTGCCGAG
Band lengths:
244-410
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)