DreEX0007464 @ danRer10
Exon Skipping
Gene
ENSDARG00000056244 | RFFL (2 of 2)
Description
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:24821]
Coordinates
chr21:25023145-25025985:+
Coord C1 exon
chr21:25023145-25023355
Coord A exon
chr21:25025359-25025382
Coord C2 exon
chr21:25025479-25025985
Length
24 bp
Sequences
Splice sites
3' ss Seq
GCTCTTTCTTTTACTTTCAGTTT
3' ss Score
9.44
5' ss Seq
CAGGTATGT
5' ss Score
9.8
Exon sequences
Seq C1 exon
TCGACAGACAGTGAGGAGACGCTGGTGCACAGCAGAAGAGCCTCTCTGTCAGATCTGAGCAGCGTGGAGGACATCGAAGGCCTCAGTGTGCGGCAGCTAAAGGAGATCCTGGCACGCAACTTTGTGAACTATCAAGGCTGCTGTGAGAAATGGGAACTAATGGAGAAGGTCACCCACCTCTTTAATGATCAGAAAGACCTTCACAACTTGG
Seq A exon
TTTCAAATACAAATACAGAAGCAG
Seq C2 exon
CTGATCCTGCGGAGCCCAGCGGACAGGAGGAGAACCTGTGTAAGATCTGCATGGACTCTCCAATTGACTGCGTGTTGCTGGAGTGTGGACACATGGTCACATGCAGCAAGTGTGGAAAACGAATGAACGAGTGTCCCATCTGCCGCCAGTATGTGGTTCGAGCCGTGCACGTCTTCAGATCGTGAAATTTGGGTGCAAAGACACAGATCGGCCCCCTGCAGGTTGTTTTCTGATAATGTTCCATTTTGCCTCTTTGTTTATCAGTTTACATTATTAAATGCACTTTTTGTTTTTTTATTGTTGCAATGGTGCGGCTTAGAAGTTATTTGCACTTTTATTTAGGCTTTGTTTTTTTTATTTCCATAATACAACATTTTTATTTCACGGTTTCTATTTCATTTCATGGTTTGGTCATATATATATATGAGCAAACAATGTTTAAAGTTGTATTGAAGACACATGTTCATTGGAAGTTTACACAAAAATGAAACCTTCCTGAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000056244_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.423 A=1.000 C2=0.098
Domain overlap (PFAM):
C1:
PF064597=RR_TM4-6=PD(28.0=62.0),PF0334410=Daxx=FE(32.4=100),PF040067=Mpp10=FE(48.3=100),PF102084=Armet=PU(90.4=93.0)
A:
PF0334410=Daxx=FE(3.7=100),PF040067=Mpp10=FE(5.5=100),PF102084=Armet=PD(8.2=66.7)
C2:
PF0334410=Daxx=PD(17.6=61.3),PF040067=Mpp10=PD(0.1=0.0),PF139201=zf-C3HC4_3=WD(100=74.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGGCTGCTGTGAGAAATGGG
R:
GGTTCTCCTCCTGTCCGCT
Band lengths:
114-138
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]