DreEX0008916 @ danRer10
Exon Skipping
Gene
ENSDARG00000102260 | TMPRSS6
Description
transmembrane protease, serine 6 [Source:HGNC Symbol;Acc:HGNC:16517]
Coordinates
chr6:210035-210764:-
Coord C1 exon
chr6:210690-210764
Coord A exon
chr6:210460-210628
Coord C2 exon
chr6:210035-210304
Length
169 bp
Sequences
Splice sites
3' ss Seq
CTCTCTGTCTCTCCCTCCAGACT
3' ss Score
12.96
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
CGTGTCTGAAGAAGCCGAACCCAGAGTGTGACTTCATCACCGACTGTCCTGATGAATCTGACGAGAAACACTGCG
Seq A exon
ACTGCGGCCTGAGGCCCTTCAGCAGCCGTATAGTGGGCGGGGCTGATGCAGTGGAGGGGGAGTGGCCATGGCAGGCCAGCCTGCAGATCAGGGGGCGGCACATATGTGGAGGGGCGTTAGTCTCCGCCCAGTGGGTGGTGTCTGCAGCTCACTGTTTCCATGATGACAG
Seq C2 exon
GTATTCCCCATCAGTGTGGACAGTGTATCTGGGTAAGCTGCGTCTGTCCAGCAGTGGTCAGTCAGAGGAGGCGGTGGGCGTCTCGCTCATTCACCTGCATCACTACTATGATGACGAGACTCATGATTACGACGTGGCGCTGCTGGCGGCTGGCGCGGCCGGTGTGGGCGGGTACGCTGGCACAGCCTGTGTGTGTGCCGCCCGTCACGCATCAGCTGGAGCCGGAGCTGCTGTGCTGGGTCACGGGATGGGGAGCGCTCAGAGAGGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000102260_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=PD(80.0=92.3)
A:
PF0008921=Trypsin=PU(20.6=80.7)
C2:
PF0008921=Trypsin=FE(17.9=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGACTGTCCTGATGAATCTGACG
R:
CTCCAGCTGATGCGTGACG
Band lengths:
256-425
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]