DreEX0010364 @ danRer10
Exon Skipping
Gene
ENSDARG00000035187 | abl1
Description
c-abl oncogene 1, non-receptor tyrosine kinase [Source:ZFIN;Acc:ZDB-GENE-100812-9]
Coordinates
chr5:71380987-71382221:+
Coord C1 exon
chr5:71380987-71381171
Coord A exon
chr5:71381594-71381746
Coord C2 exon
chr5:71382132-71382221
Length
153 bp
Sequences
Splice sites
3' ss Seq
TCTGATTTGACCTCCTTCAGCAT
3' ss Score
5.84
5' ss Seq
CCTGTAAGC
5' ss Score
3.69
Exon sequences
Seq C1 exon
GGATCTGGCAGCCCGTAACTGCTTGGTCGGGGAAAACAACCTGGTTAAAGTGGCAGATTTTGGGCTAAGCCGGCTGATGACGGGAGACACATACACAGCCCACGCTGGAGCAAAGTTCCCCATTAAATGGACTGCGCCGGAGAGTCTGGCCTATAACAAGTTCTCCATCAAGTCAGACGTGTGGG
Seq A exon
CATTTGGAGTCCTGCTTTGGGAGATCGCCACCTATGGGATGTCTCCGTATCCAGGAATCGACCTGTCTCAGGTGTATGAGCTGCTGGAGAAAGACTACCGCATGGACAGACCCGAGGGATGCCCAGAGAAAGTCTATGAGCTCATGAGGGCCT
Seq C2 exon
GTTGGAGGTGGAACCCTGCCGAGCGCCCTTCTTTTGCTGAGACCCATCAGGCGTTCGAGACCATGTTTCAAGAGTCCAGTATCTCTGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000035187-'13-16,'13-15,14-16
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.258
Domain overlap (PFAM):
C1:
PF0771412=Pkinase_Tyr=FE(24.6=100)
A:
PF0771412=Pkinase_Tyr=FE(20.2=100)
C2:
PF0771412=Pkinase_Tyr=PD(13.3=58.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATCTGGCAGCCCGTAACTG
R:
GAAACATGGTCTCGAACGCCT
Band lengths:
253-406
Functional annotations
There are 1 annotated functions for this event
PMID: 9168116
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mass detection of residue modification, mutation analysis. ELM ID: ELMI000950; ELM sequence: IDLSQVY; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]