HsaEX6063534 @ hg38
Exon Skipping
Gene
ENSG00000097007 | ABL1
Description
ABL proto-oncogene 1, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:76]
Coordinates
chr9:130874868-130880157:+
Coord C1 exon
chr9:130874868-130875052
Coord A exon
chr9:130878415-130878567
Coord C2 exon
chr9:130880068-130880157
Length
153 bp
Sequences
Splice sites
3' ss Seq
CTCTTTCGGTTTTCTTTCAGCAT
3' ss Score
9.82
5' ss Seq
CATGTAAGC
5' ss Score
5.61
Exon sequences
Seq C1 exon
AGATCTTGCTGCCCGAAACTGCCTGGTAGGGGAGAACCACTTGGTGAAGGTAGCTGATTTTGGCCTGAGCAGGTTGATGACAGGGGACACCTACACAGCCCATGCTGGAGCCAAGTTCCCCATCAAATGGACTGCACCCGAGAGCCTGGCCTACAACAAGTTCTCCATCAAGTCCGACGTCTGGG
Seq A exon
CATTTGGAGTATTGCTTTGGGAAATTGCTACCTATGGCATGTCCCCTTACCCGGGAATTGACCTGTCCCAGGTGTATGAGCTGCTAGAGAAGGACTACCGCATGGAGCGCCCAGAAGGCTGCCCAGAGAAGGTCTATGAACTCATGCGAGCAT
Seq C2 exon
GTTGGCAGTGGAATCCCTCTGACCGGCCCTCCTTTGCTGAAATCCACCAAGCCTTTGAAACAATGTTCCAGGAATCCAGTATCTCAGACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000097007-'30-29,'30-25,32-29
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.129
Domain overlap (PFAM):
C1:
PF0771412=Pkinase_Tyr=FE(24.6=100)
A:
PF0771412=Pkinase_Tyr=FE(20.2=100)
C2:
PF0771412=Pkinase_Tyr=PD(7.1=58.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGATCTTGCTGCCCGAAACTG
R:
CAAAGGCTTGGTGGATTTCAGC
Band lengths:
242-395
Functional annotations
There are 1 annotated functions for this event
PMID: 9168116
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mass detection of residue modification, mutation analysis. ELM ID: ELMI000950; ELM sequence: IDLSQVY; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains