MmuEX6100425 @ mm10
Exon Skipping
Gene
ENSMUSG00000026842 | Abl1
Description
c-abl oncogene 1, non-receptor tyrosine kinase [Source:MGI Symbol;Acc:MGI:87859]
Coordinates
chr2:31792238-31797062:+
Coord C1 exon
chr2:31792238-31792422
Coord A exon
chr2:31794542-31794694
Coord C2 exon
chr2:31796973-31797062
Length
153 bp
Sequences
Splice sites
3' ss Seq
CTTCCTCTCCTTTCTTTCAGCAT
3' ss Score
12.08
5' ss Seq
CATGTGAGC
5' ss Score
5.03
Exon sequences
Seq C1 exon
AGACCTTGCTGCCCGGAACTGCCTGGTAGGGGAAAACCACTTGGTGAAGGTGGCTGATTTTGGCCTGAGCAGGTTGATGACAGGGGACACCTACACGGCCCATGCTGGAGCCAAATTCCCCATCAAATGGACCGCACCTGAGAGCCTGGCCTACAACAAGTTCTCCATCAAGTCGGACGTGTGGG
Seq A exon
CATTTGGAGTATTGCTCTGGGAGATTGCTACCTATGGCATGTCACCTTACCCGGGAATTGACCTGTCTCAGGTTTATGAGCTGCTGGAAAAAGACTACCGCATGGAGCGCCCTGAAGGCTGCCCGGAGAAGGTCTACGAGCTCATGCGAGCAT
Seq C2 exon
GTTGGCAGTGGAACCCCTCTGACCGGCCCTCCTTTGCTGAAATCCACCAAGCCTTTGAAACCATGTTCCAGGAATCCAGTATCTCAGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026842-'45-28,'45-25,49-28
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.129
Domain overlap (PFAM):
C1:
PF0771412=Pkinase_Tyr=FE(24.6=100)
A:
PF0771412=Pkinase_Tyr=FE(20.2=100)
C2:
PF0771412=Pkinase_Tyr=PD(7.1=58.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAACTGCCTGGTAGGGGAAA
R:
CCTGGAACATGGTTTCAAAGGC
Band lengths:
243-396
Functional annotations
There are 1 annotated functions for this event
PMID: 9168116
This event
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mass detection of residue modification, mutation analysis. ELM ID: ELMI000950; ELM sequence: IDLSQVY; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types