DreEX0013090 @ danRer10
Exon Skipping
Gene
ENSDARG00000043313 | ank2b
Description
ankyrin 2b, neuronal [Source:ZFIN;Acc:ZDB-GENE-041010-165]
Coordinates
chr7:57635948-57646763:-
Coord C1 exon
chr7:57646539-57646763
Coord A exon
chr7:57636791-57636889
Coord C2 exon
chr7:57635948-57636102
Length
99 bp
Sequences
Splice sites
3' ss Seq
CTGCTGCTATTGGATTACAGTAA
3' ss Score
3.89
5' ss Seq
GGGGTAGGA
5' ss Score
4.36
Exon sequences
Seq C1 exon
TTTCTTAGTCAGCTTCATGGTGGATGCTCGAGGAGGTGCCATGCGAGGATGCCGCCACAATGGTCTGCGGCTGATCATTCCACCACGGAAGTGCAGCGCCCCTACTAGAGTCACCTGTAGACTGGTCAAAAGGCACCGACTGGCAACAATGCCTCCAATGGTAGAAGGTGACGGTCTAGCCAGCAGGCTGATTGAGGTCGGACCTTCTGGAGCTCAGTTCCTCGG
Seq A exon
TAAGCTCCACCTCCCAACTGCCCCGCCCCCTCTGAATGAGGGCGAGAGTTTGGTTAGCCGCATTCTGCAGCTGGGCCCACCAGGGACAAAATTTTTGGG
Seq C2 exon
GCCGGTGATTGTGGAGATCCCGCACTTTGCAGCTCTGAGAGGAAAAGAGAGGGAGCTGGTGATCTTACGTAGTGAAACCGGAGAGAGCTGGAAAGAGCATCACTGCGAGTACACAGAAGAAGAGCTCAACCAGGTCCTCAACGGCATGGATGAGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000043313_CASSETTE3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.053 A=0.265 C2=0.247
Domain overlap (PFAM):
C1:
PF0079115=ZU5=FE(89.3=100),PF0079115=ZU5=PU(0.1=0.0)
A:
PF0079115=ZU5=PD(8.3=20.6),PF0079115=ZU5=PU(53.2=97.1)
C2:
PF0079115=ZU5=PD(37.3=53.8)
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAAGGTGACGGTCTAGCCAG
R:
GCAGTGATGCTCTTTCCAGCT
Band lengths:
169-268
Functional annotations
There are 1 annotated functions for this event
PMID: 22749401
Inclusion enhances interaction with EPB4L2, DCTN4, SCN1B, SLC8A1, DNAJB1, CDH1, ATP1A1, SPNA2. By LUMIER.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]