DreEX0028604 @ danRer10
Exon Skipping
Gene
ENSDARG00000103195 | dync1i2b
Description
dynein, cytoplasmic 1, intermediate chain 2b [Source:ZFIN;Acc:ZDB-GENE-090121-1]
Coordinates
chr6:3778066-3782137:+
Coord C1 exon
chr6:3778066-3778156
Coord A exon
chr6:3781214-3781273
Coord C2 exon
chr6:3782022-3782137
Length
60 bp
Sequences
Splice sites
3' ss Seq
TGTATGTGTGTGTCTAACAGGAC
3' ss Score
10.38
5' ss Seq
CGGGTACTG
5' ss Score
5.43
Exon sequences
Seq C1 exon
TCCCCCCTCCCATGTCCCCTTCTGCCAAATCAGTGGGAACCCCAAGTGAGACGGGCAGCCAGGACTCCGGAGACGGCGGGACGGGCCCGAG
Seq A exon
GACTCTTCACTGGGACTCTGATCCTTCTACTCTACTGCTCCATTCAGACTCTCAGCTCGG
Seq C2 exon
ACGTGGCCCGCTTAAGTTGGGCATGTCGAAGGTCACACAGGTGGACTTTCCTCCTAAAGAGATGGTGTCGTACTCAAAAGAGACCCAGACACCCACACAGACTCATCACAAAGAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000103195_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=1.000 C2=1.000
Domain overlap (PFAM):
C1:
NO
A:
PF115403=Dynein_IC2=PU(0.1=0.0)
C2:
PF115403=Dynein_IC2=WD(100=82.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCATGTCCCCTTCTGCCAAAT
R:
GGAAAGTCCACCTGTGTGACC
Band lengths:
133-193
Functional annotations
There are 1 annotated functions for this event
PMID: 22749401
Inclusion decreases interaction with PAFAH1B1 and DYNC1I1, but not with NDEL1, DYNLRB1, DCTN1, DYNLT3, DCTN2, NR3C1. By LUMIER.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]