DreEX0045914 @ danRer10
Exon Skipping
Gene
ENSDARG00000062686 | megf11
Description
multiple EGF-like-domains 11 [Source:ZFIN;Acc:ZDB-GENE-060503-252]
Coordinates
chr18:19174009-19179300:-
Coord C1 exon
chr18:19179172-19179300
Coord A exon
chr18:19178784-19178912
Coord C2 exon
chr18:19174009-19174242
Length
129 bp
Sequences
Splice sites
3' ss Seq
TTGTATGTGTTTTTGTTCAGAGT
3' ss Score
8.35
5' ss Seq
AGGGTGACT
5' ss Score
2.76
Exon sequences
Seq C1 exon
GCTGTCCCTCAGGGTTTTATGGGCGAGACTGTGCAGAGGTGTGCCGCTGTCAAAATGGAGCTGACTGTGATCATATCACTGGCCAGTGTGCCTGTCGGACTGGCTTTATTGGGACCAACTGTGAACAGA
Seq A exon
AGTGTCCTCCCGGGACATTTGGCTATGGCTGTCAGCAGCTGTGTGAATGTATGAACAACGCCACCTGCGACTATGTGACTGGAACCTGCTACTGCAGCCCGGGATACAAAGGCATCCGCTGTGACCAGG
Seq C2 exon
CGGCTCTAGTGATGGAGGAACTCAACCCGTACACTAAGATCAGCCCCGCTCTGGGTTCAGAACGCCAGTCCGCAGGCGCCGTCATGGGCATCATCTTCCTGCTCCTGATCATCATGGCCATGCTCAGCTTGTTTGTTTGGTTCAGGCAGAGACAGAGAGACAAAGGACAGGAAATGCCCAGTGTTTCGTACACCCCAGCTCTGCGTGTCACCAACACTGACTACTCTCTTTCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000062686-'18-19,'18-18,19-19
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.038
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(70.2=75.0)
A:
PF0005319=Laminin_EGF=PD(27.7=29.5),PF0005319=Laminin_EGF=PU(82.9=65.9)
C2:
PF0005319=Laminin_EGF=PD(14.3=6.3),PF153301=SIT=PU(61.9=65.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTCAGGGTTTTATGGGCGAG
R:
GGCCATGATGATCAGGAGCAG
Band lengths:
242-371
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]