HsaEX6075437 @ hg19
Exon Skipping
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF-like-domains 11 [Source:HGNC Symbol;Acc:29635]
Coordinates
chr15:66206075-66208614:-
Coord C1 exon
chr15:66208486-66208614
Coord A exon
chr15:66207808-66207936
Coord C2 exon
chr15:66206075-66206311
Length
129 bp
Sequences
Splice sites
3' ss Seq
TAACTCTTTGTGCCACACAGGAT
3' ss Score
6.74
5' ss Seq
AAGGTAATA
5' ss Score
8.49
Exon sequences
Seq C1 exon
GCTGCCCAGCAGCATTTTTTGGGAAGGACTGTGGGCGCGTATGCCAGTGTCAGAATGGCGCCAGCTGTGACCACATCAGTGGCAAGTGCACCTGCCGCACAGGCTTCACCGGGCAACACTGTGAGCAGA
Seq A exon
GATGTGCCCCAGGAACCTTTGGCTATGGGTGTCAGCAGCTATGTGAGTGCATGAACAACTCCACCTGTGACCATGTCACCGGCACCTGTTACTGCAGCCCTGGCTTCAAAGGAATCAGGTGTGACCAAG
Seq C2 exon
CTGCCCTCATGATGGAGGAGCTGAATCCCTACACCAAGATCAGCCCAGCACTGGGTGCAGAGCGGCACTCGGTGGGTGCTGTCACAGGCATCATGCTCCTGTTATTCCTCATTGTGGTGCTGCTGGGCCTATTTGCCTGGCATCGGCGGCGGCAGAAAGAGAAGGGCCGAGACCTGGCTCCCCGTGTCTCCTACACACCTGCCATGAGGATGACCAGCACCGACTACTCCCTCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890-'25-26,'25-24,26-26=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.048 A=0.022 C2=0.053
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(63.0=65.9)
A:
PF0005319=Laminin_EGF=PD(34.8=36.4),PF0005319=Laminin_EGF=PU(78.4=65.9)
C2:
PF153301=SIT=PU(91.4=68.8),PF055456=FixQ=WD(100=46.8),PF117433=DUF3301=PU(87.3=62.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAGCTGTGACCACATCAGTG
R:
GGTCTCGGCCCTTCTCTTTCT
Band lengths:
243-372
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)