HsaEX6075437 @ hg38
Exon Skipping
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65913737-65916276:-
Coord C1 exon
chr15:65916148-65916276
Coord A exon
chr15:65915470-65915598
Coord C2 exon
chr15:65913737-65913973
Length
129 bp
Sequences
Splice sites
3' ss Seq
TAACTCTTTGTGCCACACAGGAT
3' ss Score
6.74
5' ss Seq
AAGGTAATA
5' ss Score
8.49
Exon sequences
Seq C1 exon
GCTGCCCAGCAGCATTTTTTGGGAAGGACTGTGGGCGCGTATGCCAGTGTCAGAATGGCGCCAGCTGTGACCACATCAGTGGCAAGTGCACCTGCCGCACAGGCTTCACCGGGCAACACTGTGAGCAGA
Seq A exon
GATGTGCCCCAGGAACCTTTGGCTATGGGTGTCAGCAGCTATGTGAGTGCATGAACAACTCCACCTGTGACCATGTCACCGGCACCTGTTACTGCAGCCCTGGCTTCAAAGGAATCAGGTGTGACCAAG
Seq C2 exon
CTGCCCTCATGATGGAGGAGCTGAATCCCTACACCAAGATCAGCCCAGCACTGGGTGCAGAGCGGCACTCGGTGGGTGCTGTCACAGGCATCATGCTCCTGTTATTCCTCATTGTGGTGCTGCTGGGCCTATTTGCCTGGCATCGGCGGCGGCAGAAAGAGAAGGGCCGAGACCTGGCTCCCCGTGTCTCCTACACACCTGCCATGAGGATGACCAGCACCGACTACTCCCTCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890-'41-50,'41-48,42-50=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.055 A=0.025 C2=0.071
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(63.0=65.9)
A:
PF0005319=Laminin_EGF=PD(34.8=36.4),PF0005319=Laminin_EGF=PU(78.4=65.9)
C2:
PF0005319=Laminin_EGF=PD(18.9=8.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAGCTGTGACCACATCAGTG
R:
GGTCTCGGCCCTTCTCTTTCT
Band lengths:
243-372
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains